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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
4.55
Human Site:
S452
Identified Species:
25
UniProt:
A6NES4
Number Species:
4
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NES4
XP_944799
1706
193288
S452
S
A
D
E
P
R
M
S
I
R
A
I
Y
L
A
Chimpanzee
Pan troglodytes
XP_516169
1249
141202
A103
S
V
I
I
T
E
K
A
T
T
E
P
S
V
V
Rhesus Macaque
Macaca mulatta
XP_001110486
1744
197164
S452
S
A
D
E
P
R
M
S
I
R
A
I
Y
L
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519112
1231
138043
K85
D
L
D
K
D
T
A
K
M
V
I
L
L
A
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919596
1544
173325
I398
K
L
L
I
L
A
S
I
R
Q
P
L
A
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68
89.9
N.A.
N.A.
N.A.
N.A.
N.A.
23.6
N.A.
N.A.
24.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
69.6
91.8
N.A.
N.A.
N.A.
N.A.
N.A.
41.1
N.A.
N.A.
45.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
0
0
0
20
20
20
0
0
40
0
20
20
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
60
0
20
0
0
0
0
0
0
0
0
20
0
% D
% Glu:
0
0
0
40
0
20
0
0
0
0
20
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% H
% Ile:
0
0
20
40
0
0
0
20
40
0
20
40
0
0
0
% I
% Lys:
20
0
0
20
0
0
20
20
0
0
0
0
0
0
0
% K
% Leu:
0
40
20
0
20
0
0
0
0
0
0
40
20
40
0
% L
% Met:
0
0
0
0
0
0
40
0
20
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
40
0
0
0
0
0
20
20
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
40
0
0
20
40
0
0
0
0
0
% R
% Ser:
60
0
0
0
0
0
20
40
0
0
0
0
20
0
20
% S
% Thr:
0
0
0
0
20
20
0
0
20
20
0
0
0
0
0
% T
% Val:
0
20
0
0
0
0
0
0
0
20
0
0
0
20
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _