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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL33
All Species:
2.73
Human Site:
S453
Identified Species:
7.5
UniProt:
A6NCF5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NCF5
NP_001103467
533
57810
S453
T
H
L
A
P
L
P
S
P
H
V
G
A
A
S
Chimpanzee
Pan troglodytes
XP_520667
480
51957
S400
G
E
E
C
Q
R
R
S
D
G
V
L
R
Q
L
Rhesus Macaque
Macaca mulatta
XP_001092165
453
49005
P374
H
L
A
P
L
P
S
P
H
V
G
A
A
G
A
Dog
Lupus familis
XP_539673
246
25874
P167
R
L
A
P
L
P
S
P
H
V
G
A
A
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPT1
617
69381
R533
T
P
I
A
A
M
L
R
G
Q
S
D
V
G
V
Rat
Rattus norvegicus
Q8K430
640
69714
M561
A
W
E
S
V
A
P
M
N
I
R
R
S
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLD3
629
70952
R549
T
P
I
A
A
M
L
R
G
Q
S
D
V
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RGB8
605
68516
T526
V
E
Y
Y
I
P
E
T
D
Q
W
T
T
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
T499
V
A
V
S
P
M
S
T
R
R
K
H
L
G
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.3
81.6
37.1
N.A.
25.2
23.4
N.A.
N.A.
24
N.A.
23.9
N.A.
24.2
N.A.
N.A.
N.A.
Protein Similarity:
100
70.7
82.9
39.5
N.A.
40.3
38.7
N.A.
N.A.
39.9
N.A.
39.3
N.A.
36.7
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
6.6
N.A.
13.3
6.6
N.A.
N.A.
13.3
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
13.3
N.A.
26.6
20
N.A.
N.A.
26.6
N.A.
13.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
23
34
23
12
0
0
0
0
0
23
34
12
23
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
0
0
0
0
0
0
0
23
0
0
23
0
0
0
% D
% Glu:
0
23
23
0
0
0
12
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
23
12
23
12
0
56
0
% G
% His:
12
12
0
0
0
0
0
0
23
12
0
12
0
0
12
% H
% Ile:
0
0
23
0
12
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
0
23
12
0
23
12
23
0
0
0
0
12
12
0
12
% L
% Met:
0
0
0
0
0
34
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
23
0
23
23
34
23
23
12
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
34
0
0
0
12
0
% Q
% Arg:
12
0
0
0
0
12
12
23
12
12
12
12
12
0
0
% R
% Ser:
0
0
0
23
0
0
34
23
0
0
23
0
12
0
23
% S
% Thr:
34
0
0
0
0
0
0
23
0
0
0
12
12
12
0
% T
% Val:
23
0
12
0
12
0
0
0
0
23
23
0
23
12
23
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
12
12
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _