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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRYX2
All Species:
27.27
Human Site:
T219
Identified Species:
75
UniProt:
A4D1T9
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4D1T9
NP_001008271
235
26445
T219
G
G
D
V
G
I
Y
T
N
V
Y
K
Y
V
S
Chimpanzee
Pan troglodytes
XP_527910
235
26352
T219
G
G
D
V
G
I
Y
T
N
V
Y
K
Y
V
S
Rhesus Macaque
Macaca mulatta
XP_001083561
235
26410
T219
G
G
D
V
G
I
Y
T
N
V
Y
K
Y
V
S
Dog
Lupus familis
XP_539877
270
30498
T254
G
G
D
V
G
I
Y
T
D
I
H
K
Y
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAA4
237
26679
T219
G
G
D
V
G
I
Y
T
N
I
Y
S
Y
V
P
Rat
Rattus norvegicus
P00762
246
25941
T230
P
D
N
P
G
V
Y
T
K
V
C
N
F
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518130
246
26574
T230
K
G
K
P
G
V
Y
T
K
V
C
N
Y
I
S
Chicken
Gallus gallus
Q90628
248
26069
T232
K
G
Y
P
G
V
Y
T
K
V
C
N
Y
V
S
Frog
Xenopus laevis
P19799
243
25473
T227
R
N
Y
P
G
V
Y
T
K
V
C
N
Y
N
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
96.5
72.2
N.A.
82.2
32.9
N.A.
33.7
36.2
31.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
97.8
80.3
N.A.
89.4
50.4
N.A.
53.2
53.2
51
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
80
33.3
N.A.
46.6
53.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
53.3
N.A.
60
60
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
45
0
0
0
0
% C
% Asp:
0
12
56
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
56
78
0
0
100
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
0
0
56
0
0
0
23
0
0
0
23
0
% I
% Lys:
23
0
12
0
0
0
0
0
45
0
0
45
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
12
0
0
0
0
0
45
0
0
45
0
12
0
% N
% Pro:
12
0
0
45
0
0
0
0
0
0
0
0
0
0
23
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
56
% S
% Thr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% T
% Val:
0
0
0
56
0
45
0
0
0
78
0
0
0
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
23
0
0
0
100
0
0
0
45
0
89
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _