KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC66
All Species:
5.76
Human Site:
S590
Identified Species:
18.1
UniProt:
A2RUB6
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2RUB6
NP_001012524.4
948
109411
S590
I
S
N
S
R
H
D
S
D
E
I
S
G
K
M
Chimpanzee
Pan troglodytes
XP_001173553
949
109464
D591
S
N
S
R
H
D
S
D
E
V
S
G
K
M
N
Rhesus Macaque
Macaca mulatta
XP_001097046
921
106519
S591
I
S
N
S
R
H
D
S
D
E
V
S
G
K
M
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q6NS45
935
107354
S580
K
A
F
T
T
I
S
S
S
H
S
D
P
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505474
631
73824
A307
D
I
D
I
R
G
I
A
N
L
E
V
Y
S
G
Chicken
Gallus gallus
XP_414339
916
105635
C562
G
G
G
E
F
E
N
C
N
A
D
V
S
H
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001336993
844
95875
G517
I
R
D
L
A
K
K
G
H
D
V
S
K
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786950
1119
125839
H755
P
A
Q
A
I
G
S
H
P
Q
P
T
L
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
93.3
N.A.
N.A.
68.8
N.A.
N.A.
40.8
50
N.A.
27.9
N.A.
N.A.
N.A.
N.A.
24.6
Protein Similarity:
100
99.2
94.5
N.A.
N.A.
80.5
N.A.
N.A.
51.1
65.5
N.A.
49.2
N.A.
N.A.
N.A.
N.A.
42.5
P-Site Identity:
100
0
93.3
N.A.
N.A.
6.6
N.A.
N.A.
6.6
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
N.A.
N.A.
26.6
N.A.
N.A.
26.6
13.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
13
13
0
0
13
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
13
0
25
0
0
13
25
13
25
13
13
13
0
0
0
% D
% Glu:
0
0
0
13
0
13
0
0
13
25
13
0
0
13
13
% E
% Phe:
0
0
13
0
13
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
13
13
0
0
25
0
13
0
0
0
13
25
0
13
% G
% His:
0
0
0
0
13
25
0
13
13
13
0
0
0
13
0
% H
% Ile:
38
13
0
13
13
13
13
0
0
0
13
0
0
0
0
% I
% Lys:
13
0
0
0
0
13
13
0
0
0
0
0
25
38
0
% K
% Leu:
0
0
0
13
0
0
0
0
0
13
0
0
13
13
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
25
% M
% Asn:
0
13
25
0
0
0
13
0
25
0
0
0
0
0
13
% N
% Pro:
13
0
0
0
0
0
0
0
13
0
13
0
13
0
13
% P
% Gln:
0
0
13
0
0
0
0
0
0
13
0
0
0
0
13
% Q
% Arg:
0
13
0
13
38
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
25
13
25
0
0
38
38
13
0
25
38
13
13
0
% S
% Thr:
0
0
0
13
13
0
0
0
0
0
0
13
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
13
25
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _