KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TARSL2
All Species:
19.39
Human Site:
Y248
Identified Species:
30.48
UniProt:
A2RTX5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2RTX5
NP_689547.2
802
92646
Y248
G
E
A
M
E
L
Y
Y
G
G
H
L
C
Y
G
Chimpanzee
Pan troglodytes
XP_001144545
802
92628
Y248
G
E
A
M
E
L
Y
Y
G
G
H
L
C
Y
G
Rhesus Macaque
Macaca mulatta
XP_001086926
670
78232
Y182
Y
Y
G
G
H
L
C
Y
G
P
P
I
E
N
G
Dog
Lupus familis
XP_536172
802
92150
Y248
G
E
A
M
E
L
Y
Y
G
G
H
L
C
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLY2
790
91300
Y236
G
E
A
M
E
L
Y
Y
G
G
H
L
C
Y
G
Rat
Rattus norvegicus
Q5XHY5
695
80557
F207
E
M
F
K
Y
N
K
F
K
C
R
I
L
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513531
677
78488
F189
D
M
F
K
Y
N
K
F
K
C
R
I
L
N
E
Chicken
Gallus gallus
XP_413774
903
103081
Y349
G
E
A
M
E
G
Y
Y
G
G
C
L
C
Y
G
Frog
Xenopus laevis
NP_001087812
721
82862
E218
K
Q
Q
F
E
R
L
E
V
S
K
E
T
L
L
Zebra Danio
Brachydanio rerio
NP_001116258
718
82843
E219
E
R
L
E
V
K
K
E
T
L
L
E
M
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723726
690
79327
Y201
D
L
L
E
M
F
K
Y
N
E
F
K
V
R
I
Honey Bee
Apis mellifera
XP_395662
714
83384
L219
E
M
T
K
E
D
L
L
E
M
F
K
Y
N
E
Nematode Worm
Caenorhab. elegans
P52709
725
84399
E219
K
Q
K
F
E
R
L
E
M
T
K
E
D
L
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04630
709
80918
D218
E
R
I
E
V
T
K
D
Q
A
L
E
M
F
S
Baker's Yeast
Sacchar. cerevisiae
P04801
734
84502
K219
A
K
N
V
I
K
Q
K
Q
K
F
E
R
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
75
88.5
N.A.
85.9
65.3
N.A.
73.4
67.1
65.3
65.8
N.A.
59.4
58.4
53.3
N.A.
Protein Similarity:
100
99.7
78.4
94.1
N.A.
91.5
75.6
N.A.
79
75.1
76.8
77.3
N.A.
70.8
71.9
69
N.A.
P-Site Identity:
100
100
26.6
100
N.A.
100
0
N.A.
0
86.6
6.6
0
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
100
13.3
N.A.
13.3
86.6
13.3
6.6
N.A.
6.6
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.3
49.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62
66.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
34
0
0
0
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
14
7
0
34
0
0
% C
% Asp:
14
0
0
0
0
7
0
7
0
0
0
0
7
0
0
% D
% Glu:
27
34
0
20
54
0
0
20
7
7
0
34
7
0
20
% E
% Phe:
0
0
14
14
0
7
0
14
0
0
20
0
0
14
0
% F
% Gly:
34
0
7
7
0
7
0
0
40
34
0
0
0
0
40
% G
% His:
0
0
0
0
7
0
0
0
0
0
27
0
0
0
0
% H
% Ile:
0
0
7
0
7
0
0
0
0
0
0
20
0
0
7
% I
% Lys:
14
7
7
20
0
14
34
7
14
7
14
14
0
0
7
% K
% Leu:
0
7
14
0
0
34
20
7
0
7
14
34
14
20
14
% L
% Met:
0
20
0
34
7
0
0
0
7
7
0
0
14
0
0
% M
% Asn:
0
0
7
0
0
14
0
0
7
0
0
0
0
27
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% P
% Gln:
0
14
7
0
0
0
7
0
14
0
0
0
0
0
0
% Q
% Arg:
0
14
0
0
0
14
0
0
0
0
14
0
7
7
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% S
% Thr:
0
0
7
0
0
7
0
0
7
7
0
0
7
0
0
% T
% Val:
0
0
0
7
14
0
0
0
7
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
14
0
34
47
0
0
0
0
7
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _