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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TARSL2
All Species:
16.97
Human Site:
S275
Identified Species:
26.67
UniProt:
A2RTX5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2RTX5
NP_689547.2
802
92646
S275
I
E
D
R
A
V
S
S
T
E
L
S
A
L
E
Chimpanzee
Pan troglodytes
XP_001144545
802
92628
S275
I
E
D
R
A
V
S
S
T
E
L
S
A
L
E
Rhesus Macaque
Macaca mulatta
XP_001086926
670
78232
L209
S
S
T
E
L
S
A
L
E
N
I
C
K
A
I
Dog
Lupus familis
XP_536172
802
92150
S275
I
E
D
R
A
V
S
S
T
E
L
S
A
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLY2
790
91300
S263
I
E
D
R
V
V
S
S
T
E
L
S
A
L
E
Rat
Rattus norvegicus
Q5XHY5
695
80557
R234
G
P
L
I
D
L
C
R
G
P
H
V
R
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513531
677
78488
R216
G
P
L
I
D
L
C
R
G
P
H
V
R
H
T
Chicken
Gallus gallus
XP_413774
903
103081
S376
I
E
D
R
G
V
S
S
T
E
F
P
A
L
E
Frog
Xenopus laevis
NP_001087812
721
82862
P245
L
N
E
K
V
D
T
P
T
T
T
V
Y
R
C
Zebra Danio
Brachydanio rerio
NP_001116258
718
82843
V246
V
T
T
P
T
T
T
V
Y
R
C
G
P
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723726
690
79327
D228
Y
K
C
G
S
L
I
D
L
C
R
G
P
H
V
Honey Bee
Apis mellifera
XP_395662
714
83384
C246
P
T
T
T
V
Y
R
C
G
P
L
I
D
L
C
Nematode Worm
Caenorhab. elegans
P52709
725
84399
P246
I
T
E
K
I
H
T
P
K
T
T
V
Y
R
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04630
709
80918
V245
P
A
D
M
T
I
T
V
Y
R
C
G
P
L
V
Baker's Yeast
Sacchar. cerevisiae
P04801
734
84502
V246
S
K
Y
K
T
Y
L
V
Q
T
K
V
P
D
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
75
88.5
N.A.
85.9
65.3
N.A.
73.4
67.1
65.3
65.8
N.A.
59.4
58.4
53.3
N.A.
Protein Similarity:
100
99.7
78.4
94.1
N.A.
91.5
75.6
N.A.
79
75.1
76.8
77.3
N.A.
70.8
71.9
69
N.A.
P-Site Identity:
100
100
0
100
N.A.
93.3
0
N.A.
0
80
6.6
6.6
N.A.
0
13.3
6.6
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
6.6
N.A.
6.6
80
33.3
20
N.A.
20
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.3
49.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62
66.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
20
0
7
0
0
0
0
0
34
7
0
% A
% Cys:
0
0
7
0
0
0
14
7
0
7
14
7
0
0
20
% C
% Asp:
0
0
40
0
14
7
0
7
0
0
0
0
7
7
0
% D
% Glu:
0
34
14
7
0
0
0
0
7
34
0
0
0
0
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
14
0
0
7
7
0
0
0
20
0
0
20
0
0
7
% G
% His:
0
0
0
0
0
7
0
0
0
0
14
0
0
20
0
% H
% Ile:
40
0
0
14
7
7
7
0
0
0
7
7
0
0
14
% I
% Lys:
0
14
0
20
0
0
0
0
7
0
7
0
7
0
0
% K
% Leu:
7
0
14
0
7
20
7
7
7
0
34
0
0
54
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
14
14
0
7
0
0
0
14
0
20
0
7
27
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
34
0
0
7
14
0
14
7
0
14
14
0
% R
% Ser:
14
7
0
0
7
7
34
34
0
0
0
27
0
0
0
% S
% Thr:
0
20
20
7
20
7
27
0
40
20
14
0
0
0
14
% T
% Val:
7
0
0
0
20
34
0
20
0
0
0
34
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
14
0
0
14
0
0
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _