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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HFM1
All Species:
4.85
Human Site:
S242
Identified Species:
9.7
UniProt:
A2PYH4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2PYH4
NP_001017975.3
1435
162610
S242
M
F
K
A
P
S
F
S
V
A
F
Q
P
H
D
Chimpanzee
Pan troglodytes
XP_524618
845
96632
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537081
1567
175547
L271
G
V
S
G
S
A
S
L
T
A
D
F
C
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
NP_808541
1434
161360
P241
I
F
K
A
P
S
F
P
A
A
S
Q
P
H
D
Rat
Rattus norvegicus
XP_002724973
1434
161022
S241
I
F
E
A
P
S
F
S
A
A
S
Q
P
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519189
952
107492
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919555
1228
138324
D106
Q
T
L
S
T
T
N
D
T
A
F
Q
S
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUV9
2142
244492
Y442
Y
R
K
Q
R
K
G
Y
E
E
V
H
V
P
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U2G0
2145
243812
Y436
Y
R
R
Q
K
K
S
Y
E
E
I
H
V
P
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002298526
984
111701
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189410
1133
128271
S10
T
H
T
L
K
S
V
S
D
L
P
G
N
F
R
Baker's Yeast
Sacchar. cerevisiae
P51979
1187
135053
I64
D
E
N
E
T
E
E
I
F
E
G
R
G
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.8
N.A.
43.7
N.A.
76.8
76.4
N.A.
48.7
N.A.
N.A.
47.1
N.A.
22.4
N.A.
21.9
N.A.
Protein Similarity:
100
58.2
N.A.
56.4
N.A.
86.3
85.7
N.A.
56.6
N.A.
N.A.
63.2
N.A.
38
N.A.
37.8
N.A.
P-Site Identity:
100
0
N.A.
6.6
N.A.
73.3
66.6
N.A.
0
N.A.
N.A.
20
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
0
N.A.
20
N.A.
80
80
N.A.
0
N.A.
N.A.
33.3
N.A.
6.6
N.A.
6.6
N.A.
Percent
Protein Identity:
25.7
N.A.
N.A.
24.6
26.6
N.A.
Protein Similarity:
40.8
N.A.
N.A.
41.6
43.6
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
0
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
25
0
9
0
0
17
42
0
0
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
0
0
0
0
0
0
9
9
0
9
0
0
0
25
% D
% Glu:
0
9
9
9
0
9
9
0
17
25
0
0
0
0
0
% E
% Phe:
0
25
0
0
0
0
25
0
9
0
17
9
0
9
0
% F
% Gly:
9
0
0
9
0
0
9
0
0
0
9
9
9
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
17
0
17
0
% H
% Ile:
17
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% I
% Lys:
0
0
25
0
17
17
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
9
0
0
0
9
0
9
0
0
0
9
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
9
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
25
0
0
9
0
0
9
0
25
17
9
% P
% Gln:
9
0
0
17
0
0
0
0
0
0
0
34
0
9
9
% Q
% Arg:
0
17
9
0
9
0
0
0
0
0
0
9
0
9
9
% R
% Ser:
0
0
9
9
9
34
17
25
0
0
17
0
9
0
0
% S
% Thr:
9
9
9
0
17
9
0
0
17
0
0
0
0
0
0
% T
% Val:
0
9
0
0
0
0
9
0
9
0
9
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
0
0
0
17
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _