KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HFM1
All Species:
10.91
Human Site:
S1117
Identified Species:
21.82
UniProt:
A2PYH4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2PYH4
NP_001017975.3
1435
162610
S1117
S
E
T
Q
I
S
H
S
K
H
S
D
I
S
T
Chimpanzee
Pan troglodytes
XP_524618
845
96632
A549
Q
L
Q
T
K
R
T
A
S
D
S
H
Y
V
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537081
1567
175547
S1226
S
E
T
E
I
S
H
S
K
H
S
N
R
S
T
Cat
Felis silvestris
Mouse
Mus musculus
NP_808541
1434
161360
S1115
S
E
T
D
I
S
H
S
D
Y
S
G
R
A
T
Rat
Rattus norvegicus
XP_002724973
1434
161022
S1115
S
G
T
G
L
S
H
S
E
C
S
D
R
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519189
952
107492
K657
A
D
N
Q
V
V
F
K
Q
K
I
M
D
S
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919555
1228
138324
F933
D
C
D
N
K
V
V
F
Q
Q
K
I
S
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUV9
2142
244492
P1767
Y
R
R
L
T
Q
N
P
N
Y
Y
N
L
Q
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U2G0
2145
243812
L1684
D
Y
P
I
A
D
M
L
H
M
V
G
L
A
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002298526
984
111701
F689
E
I
L
T
G
R
K
F
P
F
G
N
H
I
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189410
1133
128271
F838
T
V
K
A
D
L
I
F
E
E
Y
I
G
I
D
Baker's Yeast
Sacchar. cerevisiae
P51979
1187
135053
F891
S
S
G
E
L
I
D
F
R
R
L
Q
V
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.8
N.A.
43.7
N.A.
76.8
76.4
N.A.
48.7
N.A.
N.A.
47.1
N.A.
22.4
N.A.
21.9
N.A.
Protein Similarity:
100
58.2
N.A.
56.4
N.A.
86.3
85.7
N.A.
56.6
N.A.
N.A.
63.2
N.A.
38
N.A.
37.8
N.A.
P-Site Identity:
100
13.3
N.A.
80
N.A.
60
53.3
N.A.
13.3
N.A.
N.A.
6.6
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
20
N.A.
93.3
N.A.
73.3
73.3
N.A.
40
N.A.
N.A.
13.3
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
25.7
N.A.
N.A.
24.6
26.6
N.A.
Protein Similarity:
40.8
N.A.
N.A.
41.6
43.6
N.A.
P-Site Identity:
0
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
9
0
0
9
0
0
0
0
0
25
9
% A
% Cys:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
17
9
9
9
9
9
9
0
9
9
0
17
9
9
9
% D
% Glu:
9
25
0
17
0
0
0
0
17
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
34
0
9
0
0
0
0
0
% F
% Gly:
0
9
9
9
9
0
0
0
0
0
9
17
9
0
9
% G
% His:
0
0
0
0
0
0
34
0
9
17
0
9
9
0
0
% H
% Ile:
0
9
0
9
25
9
9
0
0
0
9
17
9
17
0
% I
% Lys:
0
0
9
0
17
0
9
9
17
9
9
0
0
0
17
% K
% Leu:
0
9
9
9
17
9
0
9
0
0
9
0
17
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
9
0
9
0
0
0
% M
% Asn:
0
0
9
9
0
0
9
0
9
0
0
25
0
9
9
% N
% Pro:
0
0
9
0
0
0
0
9
9
0
0
0
0
0
0
% P
% Gln:
9
0
9
17
0
9
0
0
17
9
0
9
0
9
0
% Q
% Arg:
0
9
9
0
0
17
0
0
9
9
0
0
25
0
0
% R
% Ser:
42
9
0
0
0
34
0
34
9
0
42
0
9
25
0
% S
% Thr:
9
0
34
17
9
0
9
0
0
0
0
0
0
0
50
% T
% Val:
0
9
0
0
9
17
9
0
0
0
9
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
0
0
0
0
17
17
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _