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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZC3H12D All Species: 10.61
Human Site: S396 Identified Species: 38.89
UniProt: A2A288 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A2A288 NP_997243.1 527 58078 S396 L S L P S P E S Q F S P G D L
Chimpanzee Pan troglodytes XP_518794 527 57829 S396 L S L P S P E S Q F S P G D L
Rhesus Macaque Macaca mulatta XP_001087043 526 57505 S396 L S L P S P E S Q F S P G D L
Dog Lupus familis XP_541146 627 68793 E507 P A I C S W Q E M R L C F Q S
Cat Felis silvestris
Mouse Mus musculus Q8BIY3 533 59322 N406 R S L R T P N N P L S P G D L
Rat Rattus norvegicus A0JPN4 596 65909 S445 G S L E S Q M S E L W G L R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511586 622 68204 W465 M S D L W S C W A G E H L E S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 94.1 45.4 N.A. 64.7 40.7 N.A. 39.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.4 95.2 51.9 N.A. 72 50 N.A. 49.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 53.3 26.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 66.6 33.3 N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 0 0 0 0 15 0 0 0 0 0 0 % A
% Cys: 0 0 0 15 0 0 15 0 0 0 0 15 0 0 0 % C
% Asp: 0 0 15 0 0 0 0 0 0 0 0 0 0 58 0 % D
% Glu: 0 0 0 15 0 0 43 15 15 0 15 0 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 43 0 0 15 0 0 % F
% Gly: 15 0 0 0 0 0 0 0 0 15 0 15 58 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % H
% Ile: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 43 0 72 15 0 0 0 0 0 29 15 0 29 0 58 % L
% Met: 15 0 0 0 0 0 15 0 15 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 15 15 0 0 0 0 0 0 0 % N
% Pro: 15 0 0 43 0 58 0 0 15 0 0 58 0 0 0 % P
% Gln: 0 0 0 0 0 15 15 0 43 0 0 0 0 15 0 % Q
% Arg: 15 0 0 15 0 0 0 0 0 15 0 0 0 15 0 % R
% Ser: 0 86 0 0 72 15 0 58 0 0 58 0 0 0 29 % S
% Thr: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 15 15 0 15 0 0 15 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _