KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
WASF2
Full Name:
Wiskott-Aldrich syndrome protein family member 2
Alias:
SCAR2; Verprolin homology domain-containing protein 2; WAS protein family, member 2; WASP-family protein member 2; WAVE2; WAVE-2 protein; Wiskott-Aldrich syndrome protein family member 2: Protein WAVE-2: Verprolin homology domain-containing protein 2
Type:
Actin binding protein
Mass (Da):
54284
Number AA:
498
UniProt ID:
Q9Y6W5
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
GO:0030027
Uniprot
OncoNet
Molecular Function:
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
GO:0007188
GO:0030036
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
P
R
H
L
C
R
Q
T
L
P
S
V
R
S
E
Site 2
S20
L
C
R
Q
T
L
P
S
V
R
S
E
L
E
C
Site 3
T29
R
S
E
L
E
C
V
T
N
I
T
L
A
N
V
Site 4
T32
L
E
C
V
T
N
I
T
L
A
N
V
I
R
Q
Site 5
S42
N
V
I
R
Q
L
G
S
L
S
K
Y
A
E
D
Site 6
S44
I
R
Q
L
G
S
L
S
K
Y
A
E
D
I
F
Site 7
Y46
Q
L
G
S
L
S
K
Y
A
E
D
I
F
G
E
Site 8
T60
E
L
F
T
Q
A
N
T
F
A
S
R
V
S
S
Site 9
S63
T
Q
A
N
T
F
A
S
R
V
S
S
L
A
E
Site 10
S66
N
T
F
A
S
R
V
S
S
L
A
E
R
V
D
Site 11
S67
T
F
A
S
R
V
S
S
L
A
E
R
V
D
R
Site 12
T80
D
R
L
Q
V
K
V
T
Q
L
D
P
K
E
E
Site 13
S90
D
P
K
E
E
E
V
S
L
Q
G
I
N
T
R
Site 14
T96
V
S
L
Q
G
I
N
T
R
K
A
F
R
S
S
Site 15
S102
N
T
R
K
A
F
R
S
S
T
I
Q
D
Q
K
Site 16
S103
T
R
K
A
F
R
S
S
T
I
Q
D
Q
K
L
Site 17
T104
R
K
A
F
R
S
S
T
I
Q
D
Q
K
L
F
Site 18
S115
Q
K
L
F
D
R
N
S
L
P
V
P
V
L
E
Site 19
Y124
P
V
P
V
L
E
T
Y
N
T
C
D
T
P
P
Site 20
T126
P
V
L
E
T
Y
N
T
C
D
T
P
P
P
L
Site 21
T129
E
T
Y
N
T
C
D
T
P
P
P
L
N
N
L
Site 22
T137
P
P
P
L
N
N
L
T
P
Y
R
D
D
G
K
Site 23
Y139
P
L
N
N
L
T
P
Y
R
D
D
G
K
E
A
Site 24
Y150
G
K
E
A
L
K
F
Y
T
D
P
S
Y
F
F
Site 25
Y155
K
F
Y
T
D
P
S
Y
F
F
D
L
W
K
E
Site 26
T168
K
E
K
M
L
Q
D
T
K
D
I
M
K
E
K
Site 27
S215
M
G
Q
E
F
V
E
S
K
E
K
L
G
T
S
Site 28
T221
E
S
K
E
K
L
G
T
S
G
Y
P
P
T
L
Site 29
S222
S
K
E
K
L
G
T
S
G
Y
P
P
T
L
V
Site 30
Y224
E
K
L
G
T
S
G
Y
P
P
T
L
V
Y
Q
Site 31
T227
G
T
S
G
Y
P
P
T
L
V
Y
Q
N
G
S
Site 32
Y230
G
Y
P
P
T
L
V
Y
Q
N
G
S
I
G
C
Site 33
S244
C
V
E
N
V
D
A
S
S
Y
P
P
P
P
Q
Site 34
S245
V
E
N
V
D
A
S
S
Y
P
P
P
P
Q
S
Site 35
Y246
E
N
V
D
A
S
S
Y
P
P
P
P
Q
S
D
Site 36
S252
S
Y
P
P
P
P
Q
S
D
S
A
S
S
P
S
Site 37
S254
P
P
P
P
Q
S
D
S
A
S
S
P
S
P
S
Site 38
S256
P
P
Q
S
D
S
A
S
S
P
S
P
S
F
S
Site 39
S257
P
Q
S
D
S
A
S
S
P
S
P
S
F
S
E
Site 40
S259
S
D
S
A
S
S
P
S
P
S
F
S
E
D
N
Site 41
S261
S
A
S
S
P
S
P
S
F
S
E
D
N
L
P
Site 42
S263
S
S
P
S
P
S
F
S
E
D
N
L
P
P
P
Site 43
S275
P
P
P
P
A
E
F
S
Y
P
V
D
N
Q
R
Site 44
Y276
P
P
P
A
E
F
S
Y
P
V
D
N
Q
R
G
Site 45
S284
P
V
D
N
Q
R
G
S
G
L
A
G
P
K
R
Site 46
S292
G
L
A
G
P
K
R
S
S
V
V
S
P
S
H
Site 47
S293
L
A
G
P
K
R
S
S
V
V
S
P
S
H
P
Site 48
S296
P
K
R
S
S
V
V
S
P
S
H
P
P
P
A
Site 49
S298
R
S
S
V
V
S
P
S
H
P
P
P
A
P
P
Site 50
S308
P
P
A
P
P
L
G
S
P
P
G
P
K
P
G
Site 51
S343
P
P
P
V
G
F
G
S
P
G
T
P
P
P
P
Site 52
T346
V
G
F
G
S
P
G
T
P
P
P
P
S
P
P
Site 53
S351
P
G
T
P
P
P
P
S
P
P
S
F
P
P
H
Site 54
S354
P
P
P
P
S
P
P
S
F
P
P
H
P
D
F
Site 55
Y375
P
P
P
P
A
A
D
Y
P
T
L
P
P
P
P
Site 56
T377
P
P
A
A
D
Y
P
T
L
P
P
P
P
L
S
Site 57
S384
T
L
P
P
P
P
L
S
Q
P
T
G
G
A
P
Site 58
T408
G
P
P
P
P
P
F
T
G
A
D
G
Q
P
A
Site 59
S421
P
A
I
P
P
P
L
S
D
T
T
K
P
K
S
Site 60
T423
I
P
P
P
L
S
D
T
T
K
P
K
S
S
L
Site 61
T424
P
P
P
L
S
D
T
T
K
P
K
S
S
L
P
Site 62
S428
S
D
T
T
K
P
K
S
S
L
P
A
V
S
D
Site 63
S434
K
S
S
L
P
A
V
S
D
A
R
S
D
L
L
Site 64
S438
P
A
V
S
D
A
R
S
D
L
L
S
A
I
R
Site 65
S442
D
A
R
S
D
L
L
S
A
I
R
Q
G
F
Q
Site 66
T471
V
V
G
N
D
V
A
T
I
L
S
R
R
I
A
Site 67
S474
N
D
V
A
T
I
L
S
R
R
I
A
V
E
Y
Site 68
Y481
S
R
R
I
A
V
E
Y
S
D
S
E
D
D
S
Site 69
S482
R
R
I
A
V
E
Y
S
D
S
E
D
D
S
S
Site 70
S484
I
A
V
E
Y
S
D
S
E
D
D
S
S
E
F
Site 71
S488
Y
S
D
S
E
D
D
S
S
E
F
D
E
D
D
Site 72
S489
S
D
S
E
D
D
S
S
E
F
D
E
D
D
W
Site 73
S497
E
F
D
E
D
D
W
S
D
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation