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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UTP18
Full Name:
U3 small nucleolar RNA-associated protein 18 homolog
Alias:
U3 small nucleolar RNA-associated protein 18 homolog: WD repeat-containing protein 50; WD repeat-containing protein 50
Type:
Mass (Da):
62004
Number AA:
556
UniProt ID:
Q9Y5J1
International Prot ID:
IPI00000733
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0005732
GO:0030529
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0030515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006364
GO:0006364
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
R
M
K
L
D
R
R
T
G
A
K
P
K
R
K
Site 2
S45
P
P
Q
K
P
A
P
S
S
Q
R
K
P
P
A
Site 3
S46
P
Q
K
P
A
P
S
S
Q
R
K
P
P
A
R
Site 4
S55
R
K
P
P
A
R
P
S
A
A
A
A
A
I
A
Site 5
S121
R
V
Q
E
H
E
D
S
G
D
S
E
V
E
N
Site 6
S124
E
H
E
D
S
G
D
S
E
V
E
N
E
A
K
Site 7
S169
K
D
M
M
K
N
A
S
E
S
K
L
S
K
D
Site 8
T200
V
P
A
W
A
E
T
T
K
R
K
T
S
S
D
Site 9
T204
A
E
T
T
K
R
K
T
S
S
D
D
E
S
E
Site 10
S205
E
T
T
K
R
K
T
S
S
D
D
E
S
E
E
Site 11
S206
T
T
K
R
K
T
S
S
D
D
E
S
E
E
D
Site 12
S210
K
T
S
S
D
D
E
S
E
E
D
E
D
D
L
Site 13
T221
E
D
D
L
L
Q
R
T
G
N
F
I
S
T
S
Site 14
S226
Q
R
T
G
N
F
I
S
T
S
T
S
L
P
R
Site 15
T227
R
T
G
N
F
I
S
T
S
T
S
L
P
R
G
Site 16
S228
T
G
N
F
I
S
T
S
T
S
L
P
R
G
I
Site 17
S230
N
F
I
S
T
S
T
S
L
P
R
G
I
L
K
Site 18
T250
H
A
N
A
E
R
P
T
V
A
R
I
S
S
V
Site 19
S255
R
P
T
V
A
R
I
S
S
V
Q
F
H
P
G
Site 20
T284
L
F
Q
V
D
G
K
T
N
P
K
I
Q
S
I
Site 21
S290
K
T
N
P
K
I
Q
S
I
Y
L
E
R
F
P
Site 22
Y292
N
P
K
I
Q
S
I
Y
L
E
R
F
P
I
F
Site 23
T313
N
G
E
E
V
L
A
T
S
T
H
S
K
V
L
Site 24
S314
G
E
E
V
L
A
T
S
T
H
S
K
V
L
Y
Site 25
S346
L
K
E
K
I
V
R
S
F
E
V
S
P
D
G
Site 26
S378
K
T
K
E
L
I
G
S
M
K
I
N
G
R
V
Site 27
S388
I
N
G
R
V
A
A
S
T
F
S
S
D
S
K
Site 28
T389
N
G
R
V
A
A
S
T
F
S
S
D
S
K
K
Site 29
S392
V
A
A
S
T
F
S
S
D
S
K
K
V
Y
A
Site 30
S394
A
S
T
F
S
S
D
S
K
K
V
Y
A
S
S
Site 31
Y398
S
S
D
S
K
K
V
Y
A
S
S
G
D
G
E
Site 32
S401
S
K
K
V
Y
A
S
S
G
D
G
E
V
Y
V
Site 33
Y407
S
S
G
D
G
E
V
Y
V
W
D
V
N
S
R
Site 34
S430
E
G
S
L
Y
G
L
S
I
A
T
S
R
N
G
Site 35
S434
Y
G
L
S
I
A
T
S
R
N
G
Q
Y
V
A
Site 36
Y439
A
T
S
R
N
G
Q
Y
V
A
C
G
S
N
C
Site 37
Y452
N
C
G
V
V
N
I
Y
N
Q
D
S
C
L
Q
Site 38
T526
K
N
I
S
H
V
H
T
M
D
F
S
P
R
S
Site 39
S530
H
V
H
T
M
D
F
S
P
R
S
G
Y
F
A
Site 40
S533
T
M
D
F
S
P
R
S
G
Y
F
A
L
G
N
Site 41
Y535
D
F
S
P
R
S
G
Y
F
A
L
G
N
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation