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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FARSA
Full Name:
Phenylalanyl-tRNA synthetase alpha chain
Alias:
CML33; FARS; FARSL; FARSLA; FRSA; PheHA; Phenylalanine tRNA ligase 1, alpha, cytoplasmic; Phenylalanine-tRNA ligase; Phenylalanine--tRNA ligase alpha chain; Phenylalanyl-tRNA synthetase, alpha subunit; PheRS; SYFA
Type:
EC 6.1.1.20; Ligase
Mass (Da):
57564
Number AA:
508
UniProt ID:
Q9Y285
International Prot ID:
IPI00031820
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005625
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004826
GO:0000049
PhosphoSite+
KinaseNET
Biological Process:
GO:0006432
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
L
L
R
R
L
E
A
S
D
G
G
L
D
S
A
Site 2
T58
I
E
A
E
L
R
S
T
K
H
W
E
L
T
A
Site 3
S75
E
E
I
A
R
E
G
S
H
E
A
R
V
F
R
Site 4
S92
P
P
E
G
L
A
Q
S
E
L
M
R
L
P
S
Site 5
S99
S
E
L
M
R
L
P
S
G
K
V
G
F
S
K
Site 6
S105
P
S
G
K
V
G
F
S
K
A
M
S
N
K
W
Site 7
S118
K
W
I
R
V
D
K
S
A
A
D
G
P
R
V
Site 8
S131
R
V
F
R
V
V
D
S
M
E
D
E
V
Q
R
Site 9
S157
K
L
G
E
K
E
R
S
E
L
R
K
R
K
L
Site 10
T172
L
A
E
V
T
L
K
T
Y
W
V
S
K
G
S
Site 11
Y173
A
E
V
T
L
K
T
Y
W
V
S
K
G
S
A
Site 12
S179
T
Y
W
V
S
K
G
S
A
F
S
T
S
I
S
Site 13
S182
V
S
K
G
S
A
F
S
T
S
I
S
K
Q
E
Site 14
T183
S
K
G
S
A
F
S
T
S
I
S
K
Q
E
T
Site 15
S184
K
G
S
A
F
S
T
S
I
S
K
Q
E
T
E
Site 16
S186
S
A
F
S
T
S
I
S
K
Q
E
T
E
L
S
Site 17
T190
T
S
I
S
K
Q
E
T
E
L
S
P
E
M
I
Site 18
S193
S
K
Q
E
T
E
L
S
P
E
M
I
S
S
G
Site 19
S199
L
S
P
E
M
I
S
S
G
S
W
R
D
R
P
Site 20
S201
P
E
M
I
S
S
G
S
W
R
D
R
P
F
K
Site 21
Y210
R
D
R
P
F
K
P
Y
N
F
L
A
H
G
V
Site 22
S232
H
P
L
L
K
V
R
S
Q
F
R
Q
I
F
L
Site 23
T248
M
G
F
T
E
M
P
T
D
N
F
I
E
S
S
Site 24
T276
P
A
R
D
Q
H
D
T
F
F
L
R
D
P
A
Site 25
Y292
A
L
Q
L
P
M
D
Y
V
Q
R
V
K
R
T
Site 26
T299
Y
V
Q
R
V
K
R
T
H
S
Q
G
G
Y
G
Site 27
S301
Q
R
V
K
R
T
H
S
Q
G
G
Y
G
S
Q
Site 28
Y305
R
T
H
S
Q
G
G
Y
G
S
Q
G
Y
K
Y
Site 29
S307
H
S
Q
G
G
Y
G
S
Q
G
Y
K
Y
N
W
Site 30
Y310
G
G
Y
G
S
Q
G
Y
K
Y
N
W
K
L
D
Site 31
Y312
Y
G
S
Q
G
Y
K
Y
N
W
K
L
D
E
A
Site 32
T326
A
R
K
N
L
L
R
T
H
T
T
S
A
S
A
Site 33
T328
K
N
L
L
R
T
H
T
T
S
A
S
A
R
A
Site 34
S330
L
L
R
T
H
T
T
S
A
S
A
R
A
L
Y
Site 35
S332
R
T
H
T
T
S
A
S
A
R
A
L
Y
R
L
Site 36
Y337
S
A
S
A
R
A
L
Y
R
L
A
Q
K
K
P
Site 37
T346
L
A
Q
K
K
P
F
T
P
V
K
Y
F
S
I
Site 38
Y350
K
P
F
T
P
V
K
Y
F
S
I
D
R
V
F
Site 39
T361
D
R
V
F
R
N
E
T
L
D
A
T
H
L
A
Site 40
T365
R
N
E
T
L
D
A
T
H
L
A
E
F
H
Q
Site 41
Y409
Q
L
R
F
K
P
A
Y
N
P
Y
T
E
P
S
Site 42
Y412
F
K
P
A
Y
N
P
Y
T
E
P
S
M
E
V
Site 43
T413
K
P
A
Y
N
P
Y
T
E
P
S
M
E
V
F
Site 44
Y422
P
S
M
E
V
F
S
Y
H
Q
G
L
K
K
W
Site 45
S435
K
W
V
E
V
G
N
S
G
V
F
R
P
E
M
Site 46
T465
G
L
S
L
E
R
P
T
M
I
K
Y
G
I
N
Site 47
Y469
E
R
P
T
M
I
K
Y
G
I
N
N
I
R
E
Site 48
Y488
K
V
N
L
Q
M
V
Y
D
S
P
L
C
R
L
Site 49
S490
N
L
Q
M
V
Y
D
S
P
L
C
R
L
D
A
Site 50
T504
A
E
P
R
P
P
P
T
Q
E
A
A
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation