KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF148
Full Name:
Zinc finger protein 148
Alias:
BERF-1; Beta enolase repressor factor 1; BFCOL1; G-rich box-binding protein; HT-BETA; PHZ-52; Transcription factor BFCOL1; Transcription factor ZBP-89; ZBP89; ZBP-89; ZFP148; Zinc finger DNA binding protein 89; ZN148
Type:
Transcription, coactivator/corepressor
Mass (Da):
88976
Number AA:
794
UniProt ID:
Q9UQR1
International Prot ID:
IPI00010833
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0043565
GO:0003704
PhosphoSite+
KinaseNET
Biological Process:
GO:0006968
GO:0000122
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
G
G
I
D
E
M
Q
S
S
R
T
M
V
V
M
Site 2
S23
G
I
D
E
M
Q
S
S
R
T
M
V
V
M
G
Site 3
T25
D
E
M
Q
S
S
R
T
M
V
V
M
G
G
V
Site 4
S36
M
G
G
V
S
G
Q
S
T
V
S
G
E
L
Q
Site 5
T37
G
G
V
S
G
Q
S
T
V
S
G
E
L
Q
D
Site 6
S39
V
S
G
Q
S
T
V
S
G
E
L
Q
D
S
V
Site 7
S45
V
S
G
E
L
Q
D
S
V
L
Q
D
R
S
M
Site 8
S51
D
S
V
L
Q
D
R
S
M
P
H
Q
E
I
L
Site 9
S67
A
D
E
V
L
Q
E
S
E
M
R
Q
Q
D
M
Site 10
T96
N
D
E
E
Q
M
E
T
H
E
R
L
P
Q
G
Site 11
Y106
R
L
P
Q
G
L
Q
Y
A
L
N
V
P
I
S
Site 12
T119
I
S
V
K
Q
E
I
T
F
T
D
V
S
E
Q
Site 13
T121
V
K
Q
E
I
T
F
T
D
V
S
E
Q
L
M
Site 14
S124
E
I
T
F
T
D
V
S
E
Q
L
M
R
D
K
Site 15
S150
K
K
K
R
K
Q
R
S
P
A
K
I
L
T
I
Site 16
T156
R
S
P
A
K
I
L
T
I
N
E
D
G
S
L
Site 17
S162
L
T
I
N
E
D
G
S
L
G
L
K
T
P
K
Site 18
T167
D
G
S
L
G
L
K
T
P
K
S
H
V
C
E
Site 19
Y184
N
A
A
F
R
T
N
Y
H
L
Q
R
H
V
F
Site 20
T194
Q
R
H
V
F
I
H
T
G
E
K
P
F
Q
C
Site 21
S202
G
E
K
P
F
Q
C
S
Q
C
D
M
R
F
I
Site 22
Y212
D
M
R
F
I
Q
K
Y
L
L
Q
R
H
E
K
Site 23
T222
Q
R
H
E
K
I
H
T
G
E
K
P
F
R
C
Site 24
Y240
G
M
R
F
I
Q
K
Y
H
M
E
R
H
K
R
Site 25
S250
E
R
H
K
R
T
H
S
G
E
K
P
Y
Q
C
Site 26
Y259
E
K
P
Y
Q
C
E
Y
C
L
Q
Y
F
S
R
Site 27
Y263
Q
C
E
Y
C
L
Q
Y
F
S
R
T
D
R
V
Site 28
T267
C
L
Q
Y
F
S
R
T
D
R
V
L
K
H
K
Site 29
S297
I
K
G
G
L
L
T
S
E
E
D
S
G
F
S
Site 30
S301
L
L
T
S
E
E
D
S
G
F
S
T
S
P
K
Site 31
S304
S
E
E
D
S
G
F
S
T
S
P
K
D
N
S
Site 32
T305
E
E
D
S
G
F
S
T
S
P
K
D
N
S
L
Site 33
S306
E
D
S
G
F
S
T
S
P
K
D
N
S
L
P
Site 34
S311
S
T
S
P
K
D
N
S
L
P
K
K
K
R
Q
Site 35
T320
P
K
K
K
R
Q
K
T
E
K
K
S
S
G
M
Site 36
S331
S
S
G
M
D
K
E
S
A
L
D
K
S
D
L
Site 37
S336
K
E
S
A
L
D
K
S
D
L
K
K
D
K
N
Site 38
Y345
L
K
K
D
K
N
D
Y
L
P
L
Y
S
S
S
Site 39
Y349
K
N
D
Y
L
P
L
Y
S
S
S
T
K
V
K
Site 40
S350
N
D
Y
L
P
L
Y
S
S
S
T
K
V
K
D
Site 41
S351
D
Y
L
P
L
Y
S
S
S
T
K
V
K
D
E
Site 42
S352
Y
L
P
L
Y
S
S
S
T
K
V
K
D
E
Y
Site 43
Y359
S
T
K
V
K
D
E
Y
M
V
A
E
Y
A
V
Site 44
Y364
D
E
Y
M
V
A
E
Y
A
V
E
M
P
H
S
Site 45
S371
Y
A
V
E
M
P
H
S
S
V
G
G
S
H
L
Site 46
S372
A
V
E
M
P
H
S
S
V
G
G
S
H
L
E
Site 47
S376
P
H
S
S
V
G
G
S
H
L
E
D
A
S
G
Site 48
S382
G
S
H
L
E
D
A
S
G
E
I
H
P
P
K
Site 49
S397
L
V
L
K
K
I
N
S
K
R
S
L
K
Q
P
Site 50
S400
K
K
I
N
S
K
R
S
L
K
Q
P
L
E
Q
Site 51
T410
Q
P
L
E
Q
N
Q
T
I
S
P
L
S
T
Y
Site 52
S412
L
E
Q
N
Q
T
I
S
P
L
S
T
Y
E
E
Site 53
S415
N
Q
T
I
S
P
L
S
T
Y
E
E
S
K
V
Site 54
T416
Q
T
I
S
P
L
S
T
Y
E
E
S
K
V
S
Site 55
Y417
T
I
S
P
L
S
T
Y
E
E
S
K
V
S
K
Site 56
S420
P
L
S
T
Y
E
E
S
K
V
S
K
Y
A
F
Site 57
S423
T
Y
E
E
S
K
V
S
K
Y
A
F
E
L
V
Site 58
Y425
E
E
S
K
V
S
K
Y
A
F
E
L
V
D
K
Site 59
S455
D
N
L
Q
E
G
P
S
K
P
V
H
S
S
T
Site 60
Y464
P
V
H
S
S
T
N
Y
D
D
A
M
Q
F
L
Site 61
Y476
Q
F
L
K
K
K
R
Y
L
Q
A
A
S
N
N
Site 62
Y487
A
S
N
N
S
R
E
Y
A
L
N
V
G
T
I
Site 63
S516
I
D
E
S
T
T
A
S
I
L
E
S
Q
A
L
Site 64
S529
A
L
N
V
E
I
K
S
N
H
D
K
N
V
I
Site 65
T543
I
P
D
E
V
L
Q
T
L
L
D
H
Y
S
H
Site 66
Y548
L
Q
T
L
L
D
H
Y
S
H
K
A
N
G
Q
Site 67
S559
A
N
G
Q
H
E
I
S
F
S
V
A
D
T
E
Site 68
S561
G
Q
H
E
I
S
F
S
V
A
D
T
E
V
T
Site 69
T568
S
V
A
D
T
E
V
T
S
S
I
S
I
N
S
Site 70
S570
A
D
T
E
V
T
S
S
I
S
I
N
S
S
E
Site 71
S572
T
E
V
T
S
S
I
S
I
N
S
S
E
V
P
Site 72
S576
S
S
I
S
I
N
S
S
E
V
P
E
V
T
P
Site 73
T582
S
S
E
V
P
E
V
T
P
S
E
N
V
G
S
Site 74
S584
E
V
P
E
V
T
P
S
E
N
V
G
S
S
S
Site 75
S589
T
P
S
E
N
V
G
S
S
S
Q
A
S
S
S
Site 76
S590
P
S
E
N
V
G
S
S
S
Q
A
S
S
S
D
Site 77
S591
S
E
N
V
G
S
S
S
Q
A
S
S
S
D
K
Site 78
S594
V
G
S
S
S
Q
A
S
S
S
D
K
A
N
M
Site 79
S595
G
S
S
S
Q
A
S
S
S
D
K
A
N
M
L
Site 80
S596
S
S
S
Q
A
S
S
S
D
K
A
N
M
L
Q
Site 81
S617
Q
Q
A
L
D
R
T
S
Q
N
D
A
Y
L
N
Site 82
Y622
R
T
S
Q
N
D
A
Y
L
N
S
P
S
L
N
Site 83
S625
Q
N
D
A
Y
L
N
S
P
S
L
N
F
V
T
Site 84
S627
D
A
Y
L
N
S
P
S
L
N
F
V
T
D
N
Site 85
T636
N
F
V
T
D
N
Q
T
L
P
N
Q
P
A
F
Site 86
S644
L
P
N
Q
P
A
F
S
S
I
D
K
Q
V
Y
Site 87
Y651
S
S
I
D
K
Q
V
Y
A
T
M
P
I
N
S
Site 88
S658
Y
A
T
M
P
I
N
S
F
R
S
G
M
N
S
Site 89
S661
M
P
I
N
S
F
R
S
G
M
N
S
P
L
R
Site 90
S665
S
F
R
S
G
M
N
S
P
L
R
T
T
P
D
Site 91
T669
G
M
N
S
P
L
R
T
T
P
D
K
S
H
F
Site 92
T670
M
N
S
P
L
R
T
T
P
D
K
S
H
F
G
Site 93
S674
L
R
T
T
P
D
K
S
H
F
G
L
I
V
G
Site 94
S686
I
V
G
D
S
Q
H
S
F
P
F
S
G
D
E
Site 95
S690
S
Q
H
S
F
P
F
S
G
D
E
T
N
H
A
Site 96
T694
F
P
F
S
G
D
E
T
N
H
A
S
A
T
S
Site 97
S698
G
D
E
T
N
H
A
S
A
T
S
T
Q
D
F
Site 98
T702
N
H
A
S
A
T
S
T
Q
D
F
L
D
Q
V
Site 99
S711
D
F
L
D
Q
V
T
S
Q
K
K
A
E
A
Q
Site 100
Y724
A
Q
P
V
H
Q
A
Y
Q
M
S
S
F
E
Q
Site 101
S728
H
Q
A
Y
Q
M
S
S
F
E
Q
P
F
R
A
Site 102
Y737
E
Q
P
F
R
A
P
Y
H
G
S
R
A
G
I
Site 103
T746
G
S
R
A
G
I
A
T
Q
F
S
T
A
N
G
Site 104
S749
A
G
I
A
T
Q
F
S
T
A
N
G
Q
V
N
Site 105
T762
V
N
L
R
G
P
G
T
S
A
E
F
S
E
F
Site 106
S763
N
L
R
G
P
G
T
S
A
E
F
S
E
F
P
Site 107
S783
D
N
R
A
G
M
T
S
S
P
D
A
T
T
G
Site 108
S784
N
R
A
G
M
T
S
S
P
D
A
T
T
G
Q
Site 109
T788
M
T
S
S
P
D
A
T
T
G
Q
T
F
G
_
Site 110
T789
T
S
S
P
D
A
T
T
G
Q
T
F
G
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation