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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STUB1
Full Name:
STIP1 homology and U box-containing protein 1
Alias:
Antigen NY-CO-7; Carboxy terminus of Hsp70-interacting protein; CHIP; CLL-associated antigen KW-8; E3 ubiquitin-protein ligase CHIP; Heat shock protein A binding protein 2 (c-terminal); HSPABP2; NY-CO-7; SDCCAG7; Serologically defined colon cancer antigen 7; STIP1 homology and U-Box containing protein 1; STIP1y and U-box containing protein 1; UBOX1
Type:
Adaptor/scaffold; EC 6.3.2.-; Ubiquitin ligase; Ligase; Ubiquitin conjugating system
Mass (Da):
34856
Number AA:
303
UniProt ID:
Q9UNE7
International Prot ID:
IPI00025156
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0031371
GO:0000151
Uniprot
OncoNet
Molecular Function:
GO:0030544
GO:0051879
GO:0046332
PhosphoSite+
KinaseNET
Biological Process:
GO:0032436
GO:0031398
GO:0043161
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
R
L
G
A
G
G
G
S
P
E
K
S
P
S
A
Site 2
S23
G
G
G
S
P
E
K
S
P
S
A
Q
E
L
K
Site 3
S25
G
S
P
E
K
S
P
S
A
Q
E
L
K
E
Q
Site 4
Y42
R
L
F
V
G
R
K
Y
P
E
A
A
A
C
Y
Site 5
Y49
Y
P
E
A
A
A
C
Y
G
R
A
I
T
R
N
Site 6
Y70
Y
T
N
R
A
L
C
Y
L
K
M
Q
Q
H
E
Site 7
Y110
C
Q
L
E
M
E
S
Y
D
E
A
I
A
N
L
Site 8
Y121
I
A
N
L
Q
R
A
Y
S
L
A
K
E
Q
R
Site 9
S122
A
N
L
Q
R
A
Y
S
L
A
K
E
Q
R
L
Site 10
S137
N
F
G
D
D
I
P
S
A
L
R
I
A
K
K
Site 11
S149
A
K
K
K
R
W
N
S
I
E
E
R
R
I
H
Site 12
S159
E
R
R
I
H
Q
E
S
E
L
H
S
Y
L
S
Site 13
S163
H
Q
E
S
E
L
H
S
Y
L
S
R
L
I
A
Site 14
Y164
Q
E
S
E
L
H
S
Y
L
S
R
L
I
A
A
Site 15
S191
H
E
G
D
E
D
D
S
H
V
R
A
Q
Q
A
Site 16
Y207
I
E
A
K
H
D
K
Y
M
A
D
M
D
E
L
Site 17
S216
A
D
M
D
E
L
F
S
Q
V
D
E
K
R
K
Site 18
Y230
K
K
R
D
I
P
D
Y
L
C
G
K
I
S
F
Site 19
S236
D
Y
L
C
G
K
I
S
F
E
L
M
R
E
P
Site 20
T246
L
M
R
E
P
C
I
T
P
S
G
I
T
Y
D
Site 21
Y252
I
T
P
S
G
I
T
Y
D
R
K
D
I
E
E
Site 22
T271
V
G
H
F
D
P
V
T
R
S
P
L
T
Q
E
Site 23
S273
H
F
D
P
V
T
R
S
P
L
T
Q
E
Q
L
Site 24
T276
P
V
T
R
S
P
L
T
Q
E
Q
L
I
P
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation