KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
Cbl-c
Full Name:
Signal transduction protein CBL-C
Alias:
Cas-Br-M (murine) ecotropic retroviral transforming sequence c; CBL3; CBL-3; CBLC; CBL-SL; RING finger protein 57; RNF57; SH3-binding protein CBL-C
Type:
Catenin-delta-1 isoform 12
Mass (Da):
52456
Number AA:
474
UniProt ID:
Q9ULV8
International Prot ID:
IPI00008459
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0017124
GO:0005509
GO:0005154
PhosphoSite+
KinaseNET
Biological Process:
GO:0007166
GO:0043407
GO:0007175
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S38
Q
C
V
D
P
R
L
S
V
S
P
P
S
L
R
Site 2
S40
V
D
P
R
L
S
V
S
P
P
S
L
R
D
L
Site 3
S43
R
L
S
V
S
P
P
S
L
R
D
L
L
P
R
Site 4
S61
L
L
R
E
V
A
H
S
R
R
A
A
G
G
G
Site 5
S105
L
P
P
R
G
R
R
S
A
N
D
E
L
F
R
Site 6
S115
D
E
L
F
R
A
G
S
R
L
R
R
Q
L
A
Site 7
Y144
A
L
F
P
G
G
K
Y
C
G
H
M
Y
Q
L
Site 8
T158
L
T
K
A
P
A
H
T
F
W
R
E
S
C
G
Site 9
T181
E
F
E
S
L
L
G
T
C
H
P
V
E
P
G
Site 10
T223
R
L
F
Q
P
W
P
T
L
L
K
N
W
Q
L
Site 11
T243
P
G
Y
M
A
F
L
T
Y
D
E
V
Q
E
R
Site 12
Y244
G
Y
M
A
F
L
T
Y
D
E
V
Q
E
R
L
Site 13
S260
A
C
R
D
K
P
G
S
Y
I
F
R
P
S
C
Site 14
S279
Q
W
A
I
G
Y
V
S
S
D
G
S
I
L
Q
Site 15
T287
S
D
G
S
I
L
Q
T
I
P
A
N
K
P
L
Site 16
S295
I
P
A
N
K
P
L
S
Q
V
L
L
E
G
Q
Site 17
Y307
E
G
Q
K
D
G
F
Y
L
Y
P
D
G
K
T
Site 18
Y309
Q
K
D
G
F
Y
L
Y
P
D
G
K
T
H
N
Site 19
T314
Y
L
Y
P
D
G
K
T
H
N
P
D
L
T
E
Site 20
T320
K
T
H
N
P
D
L
T
E
L
G
Q
A
E
P
Site 21
S334
P
Q
Q
R
I
H
V
S
E
E
Q
L
Q
L
Y
Site 22
Y341
S
E
E
Q
L
Q
L
Y
W
A
M
D
S
T
F
Site 23
Y402
G
W
E
A
V
S
I
Y
Q
F
H
G
Q
A
T
Site 24
S413
G
Q
A
T
A
E
D
S
G
N
S
S
D
Q
E
Site 25
S417
A
E
D
S
G
N
S
S
D
Q
E
G
R
E
L
Site 26
S432
E
L
G
Q
V
P
L
S
A
P
P
L
P
P
R
Site 27
S461
V
R
L
L
K
G
N
S
P
P
A
A
L
G
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation