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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXO5
Full Name:
F-box only protein 5
Alias:
Early mitotic inhibitor 1; EMI1; Emi1; F-box protein 5; Fbxo31
Type:
Mass (Da):
50146
Number AA:
447
UniProt ID:
Q9UKT4
International Prot ID:
IPI00016633
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005654
GO:0005819
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0019941
GO:0051436
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
R
R
P
C
S
C
A
L
R
P
P
R
Site 2
S16
A
L
R
P
P
R
C
S
C
S
A
S
P
S
A
Site 3
S18
R
P
P
R
C
S
C
S
A
S
P
S
A
V
T
Site 4
S20
P
R
C
S
C
S
A
S
P
S
A
V
T
A
A
Site 5
S22
C
S
C
S
A
S
P
S
A
V
T
A
A
G
R
Site 6
S33
A
A
G
R
P
R
P
S
D
S
C
K
E
E
S
Site 7
S35
G
R
P
R
P
S
D
S
C
K
E
E
S
S
T
Site 8
S40
S
D
S
C
K
E
E
S
S
T
L
S
V
K
M
Site 9
T42
S
C
K
E
E
S
S
T
L
S
V
K
M
K
C
Site 10
S44
K
E
E
S
S
T
L
S
V
K
M
K
C
D
F
Site 11
S73
D
D
I
G
R
L
V
S
Y
T
P
A
Y
L
E
Site 12
Y74
D
I
G
R
L
V
S
Y
T
P
A
Y
L
E
G
Site 13
Y78
L
V
S
Y
T
P
A
Y
L
E
G
S
C
K
D
Site 14
Y90
C
K
D
C
I
K
D
Y
E
R
L
S
C
I
G
Site 15
S94
I
K
D
Y
E
R
L
S
C
I
G
S
P
I
V
Site 16
S98
E
R
L
S
C
I
G
S
P
I
V
S
P
R
I
Site 17
S102
C
I
G
S
P
I
V
S
P
R
I
V
Q
L
E
Site 18
T110
P
R
I
V
Q
L
E
T
E
S
K
R
L
H
N
Site 19
T138
N
E
I
E
A
L
E
T
S
R
L
Y
E
D
S
Site 20
Y142
A
L
E
T
S
R
L
Y
E
D
S
G
Y
S
S
Site 21
S145
T
S
R
L
Y
E
D
S
G
Y
S
S
F
S
L
Site 22
Y147
R
L
Y
E
D
S
G
Y
S
S
F
S
L
Q
S
Site 23
S149
Y
E
D
S
G
Y
S
S
F
S
L
Q
S
G
L
Site 24
S151
D
S
G
Y
S
S
F
S
L
Q
S
G
L
S
E
Site 25
S157
F
S
L
Q
S
G
L
S
E
H
E
E
G
S
L
Site 26
S163
L
S
E
H
E
E
G
S
L
L
E
E
N
F
G
Site 27
S172
L
E
E
N
F
G
D
S
L
Q
S
C
L
L
Q
Site 28
S182
S
C
L
L
Q
I
Q
S
P
D
Q
Y
P
N
K
Site 29
Y186
Q
I
Q
S
P
D
Q
Y
P
N
K
N
L
L
P
Site 30
T279
I
N
V
S
K
V
S
T
T
W
K
K
I
L
E
Site 31
T303
S
K
A
I
Q
R
V
T
E
N
N
N
K
F
S
Site 32
S310
T
E
N
N
N
K
F
S
P
H
A
S
T
R
E
Site 33
S314
N
K
F
S
P
H
A
S
T
R
E
Y
V
M
F
Site 34
Y318
P
H
A
S
T
R
E
Y
V
M
F
R
T
P
L
Site 35
T323
R
E
Y
V
M
F
R
T
P
L
A
S
V
Q
K
Site 36
S327
M
F
R
T
P
L
A
S
V
Q
K
S
A
A
Q
Site 37
S331
P
L
A
S
V
Q
K
S
A
A
Q
T
S
L
K
Site 38
Y356
G
D
Q
K
G
S
T
Y
S
R
H
N
E
F
S
Site 39
S363
Y
S
R
H
N
E
F
S
E
V
A
K
T
L
K
Site 40
T368
E
F
S
E
V
A
K
T
L
K
K
N
E
S
L
Site 41
S374
K
T
L
K
K
N
E
S
L
K
A
C
I
R
C
Site 42
Y387
R
C
N
S
P
A
K
Y
D
C
Y
L
Q
R
A
Site 43
Y390
S
P
A
K
Y
D
C
Y
L
Q
R
A
T
C
K
Site 44
S420
Y
H
T
T
K
D
C
S
D
G
K
L
L
K
A
Site 45
S428
D
G
K
L
L
K
A
S
C
K
I
G
P
L
P
Site 46
T437
K
I
G
P
L
P
G
T
K
K
S
K
K
N
L
Site 47
S440
P
L
P
G
T
K
K
S
K
K
N
L
R
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation