PhosphoNET

           
Protein Info 
   
Short Name:  LEF1
Full Name:  Lymphoid enhancer-binding factor 1
Alias: 
Type:  Transcription protein
Mass (Da):  44201
Number AA:  399
UniProt ID:  Q9UJU2
International Prot ID:  IPI00007156
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:  GO:0008301  GO:0005515  GO:0043565 PhosphoSite+ KinaseNET
Biological Process:  GO:0016055  GO:0001837  GO:0060021 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T20GDPELCATDEMIPFK
Site 2S42EKIFAEISHPEEEGD
Site 3S55GDLADIKSSLVNESE
Site 4S56DLADIKSSLVNESEI
Site 5S61KSSLVNESEIIPASN
Site 6S67ESEIIPASNGHEVAR
Site 7S79VARQAQTSQEPYHDK
Site 8Y83AQTSQEPYHDKAREH
Site 9Y102KHPDGGLYNKGPSYS
Site 10S107GLYNKGPSYSSYSGY
Site 11Y108LYNKGPSYSSYSGYI
Site 12S109YNKGPSYSSYSGYIM
Site 13S110NKGPSYSSYSGYIMM
Site 14Y111KGPSYSSYSGYIMMP
Site 15S112GPSYSSYSGYIMMPN
Site 16Y114SYSSYSGYIMMPNMN
Site 17Y125PNMNNDPYMSNGSLS
Site 18S127MNNDPYMSNGSLSPP
Site 19S130DPYMSNGSLSPPIPR
Site 20S132YMSNGSLSPPIPRTS
Site 21T138LSPPIPRTSNKVPVV
Site 22S139SPPIPRTSNKVPVVQ
Site 23T155SHAVHPLTPLITYSD
Site 24T159HPLTPLITYSDEHFS
Site 25Y160PLTPLITYSDEHFSP
Site 26S161LTPLITYSDEHFSPG
Site 27S166TYSDEHFSPGSHPSH
Site 28S169DEHFSPGSHPSHIPS
Site 29S172FSPGSHPSHIPSDVN
Site 30S176SHPSHIPSDVNSKQG
Site 31S180HIPSDVNSKQGMSRH
Site 32T195PPAPDIPTFYPLSPG
Site 33Y197APDIPTFYPLSPGGV
Site 34S200IPTFYPLSPGGVGQI
Site 35T208PGGVGQITPPLGWQG
Site 36Y219GWQGQPVYPITGGFR
Site 37T222GQPVYPITGGFRQPY
Site 38Y229TGGFRQPYPSSLSVD
Site 39S231GFRQPYPSSLSVDTS
Site 40S232FRQPYPSSLSVDTSM
Site 41S234QPYPSSLSVDTSMSR
Site 42T237PSSLSVDTSMSRFSH
Site 43S238SSLSVDTSMSRFSHH
Site 44S240LSVDTSMSRFSHHMI
Site 45S243DTSMSRFSHHMIPGP
Site 46T255PGPPGPHTTGIPHPA
Site 47T256GPPGPHTTGIPHPAI
Site 48T265IPHPAIVTPQVKQEH
Site 49T275VKQEHPHTDSDLMHV
Site 50S277QEHPHTDSDLMHVKP
Site 51Y309PLNAFMLYMKEMRAN
Site 52S341GRRWHALSREEQAKY
Site 53Y348SREEQAKYYELARKE
Site 54Y349REEQAKYYELARKER
Site 55Y363RQLHMQLYPGWSARD
Site 56Y372GWSARDNYGKKKKRK
Site 57S386KREKLQESASGTGPR
Site 58S388EKLQESASGTGPRMT
Site 59T390LQESASGTGPRMTAA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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