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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STAP2
Full Name:
Signal-transducing adaptor protein 2
Alias:
BKS; Breast tumor kinase substrate; STAP-2
Type:
Adaptor/scaffold
Mass (Da):
44894
Number AA:
403
UniProt ID:
Q9UGK3
International Prot ID:
IPI00383883
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
K
P
K
G
V
L
P
S
H
Y
Y
E
S
F
L
Site 2
Y21
K
G
V
L
P
S
H
Y
Y
E
S
F
L
E
K
Site 3
Y22
G
V
L
P
S
H
Y
Y
E
S
F
L
E
K
K
Site 4
S24
L
P
S
H
Y
Y
E
S
F
L
E
K
K
G
P
Site 5
Y36
K
G
P
C
D
R
D
Y
K
K
F
W
A
G
L
Site 6
Y49
G
L
Q
G
L
T
I
Y
F
Y
N
S
N
R
D
Site 7
Y51
Q
G
L
T
I
Y
F
Y
N
S
N
R
D
F
Q
Site 8
T72
L
G
A
F
E
K
L
T
D
E
I
P
W
G
S
Site 9
S79
T
D
E
I
P
W
G
S
S
R
D
P
G
T
H
Site 10
S80
D
E
I
P
W
G
S
S
R
D
P
G
T
H
F
Site 11
T85
G
S
S
R
D
P
G
T
H
F
S
L
I
L
R
Site 12
S88
R
D
P
G
T
H
F
S
L
I
L
R
D
Q
E
Site 13
T150
E
A
R
R
A
L
E
T
P
S
C
F
L
K
V
Site 14
S152
R
R
A
L
E
T
P
S
C
F
L
K
V
S
R
Site 15
S180
G
N
L
L
L
R
P
S
G
D
G
A
D
G
V
Site 16
S188
G
D
G
A
D
G
V
S
V
T
T
R
Q
M
H
Site 17
T190
G
A
D
G
V
S
V
T
T
R
Q
M
H
N
G
Site 18
Y204
G
T
H
V
V
R
H
Y
K
V
K
R
E
G
P
Site 19
Y213
V
K
R
E
G
P
K
Y
V
I
D
V
E
Q
P
Site 20
S225
E
Q
P
F
S
C
T
S
L
D
A
V
V
N
Y
Site 21
Y232
S
L
D
A
V
V
N
Y
F
V
S
H
T
K
K
Site 22
Y250
P
F
L
L
D
E
D
Y
E
K
V
L
G
Y
V
Site 23
Y256
D
Y
E
K
V
L
G
Y
V
E
A
D
K
E
N
Site 24
S272
E
N
V
W
V
A
P
S
A
P
G
P
G
P
A
Site 25
T282
G
P
G
P
A
P
C
T
G
G
P
K
P
L
S
Site 26
S289
T
G
G
P
K
P
L
S
P
A
S
S
Q
D
K
Site 27
S292
P
K
P
L
S
P
A
S
S
Q
D
K
L
P
P
Site 28
S293
K
P
L
S
P
A
S
S
Q
D
K
L
P
P
L
Site 29
Y310
L
P
N
Q
E
E
N
Y
V
T
P
I
G
D
G
Site 30
T312
N
Q
E
E
N
Y
V
T
P
I
G
D
G
P
A
Site 31
Y322
G
D
G
P
A
V
D
Y
E
N
Q
D
V
A
S
Site 32
S331
N
Q
D
V
A
S
S
S
W
P
V
I
L
K
P
Site 33
S373
L
G
R
K
L
P
V
S
S
A
Q
P
L
F
P
Site 34
S374
G
R
K
L
P
V
S
S
A
Q
P
L
F
P
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation