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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TFIP11
Full Name:
Tuftelin-interacting protein 11
Alias:
DKFZP434B194; HSPC006; Septin and tuftelin-interacting protein 1; TFP11; TIP39; TP11; Tuftelin interacting protein 11; Tuftelin-interacting protein 39
Type:
RNA binding protein
Mass (Da):
96820
Number AA:
837
UniProt ID:
Q9UBB9
International Prot ID:
IPI00015924
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
GO:0005622
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0001503
GO:0006139
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
S
L
S
H
L
Y
R
D
G
E
G
R
I
Site 2
T50
W
Q
T
K
E
E
A
T
Y
G
V
W
A
E
R
Site 3
Y51
Q
T
K
E
E
A
T
Y
G
V
W
A
E
R
D
Site 4
S59
G
V
W
A
E
R
D
S
D
D
E
R
P
S
F
Site 5
S65
D
S
D
D
E
R
P
S
F
G
G
K
R
A
R
Site 6
Y74
G
G
K
R
A
R
D
Y
S
A
P
V
N
F
I
Site 7
S75
G
K
R
A
R
D
Y
S
A
P
V
N
F
I
S
Site 8
S82
S
A
P
V
N
F
I
S
A
G
L
K
K
G
A
Site 9
S98
E
E
A
E
L
E
D
S
D
D
E
E
K
P
V
Site 10
T121
F
G
P
R
K
L
K
T
G
G
N
F
K
P
S
Site 11
S128
T
G
G
N
F
K
P
S
Q
K
G
F
A
G
G
Site 12
S138
G
F
A
G
G
T
K
S
F
M
D
F
G
S
W
Site 13
S144
K
S
F
M
D
F
G
S
W
E
R
H
T
K
G
Site 14
T149
F
G
S
W
E
R
H
T
K
G
I
G
Q
K
L
Site 15
Y162
K
L
L
Q
K
M
G
Y
V
P
G
R
G
L
G
Site 16
S195
G
A
V
G
A
Y
G
S
E
R
T
T
Q
S
M
Site 17
T199
A
Y
G
S
E
R
T
T
Q
S
M
Q
D
F
P
Site 18
S201
G
S
E
R
T
T
Q
S
M
Q
D
F
P
V
V
Site 19
S210
Q
D
F
P
V
V
D
S
E
E
E
A
E
E
E
Site 20
S223
E
E
F
Q
K
E
L
S
Q
W
R
K
D
P
S
Site 21
S230
S
Q
W
R
K
D
P
S
G
S
K
K
K
P
K
Site 22
Y238
G
S
K
K
K
P
K
Y
S
Y
K
T
V
E
E
Site 23
S239
S
K
K
K
P
K
Y
S
Y
K
T
V
E
E
L
Site 24
T242
K
P
K
Y
S
Y
K
T
V
E
E
L
K
A
K
Site 25
S253
L
K
A
K
G
R
I
S
K
K
L
T
A
P
Q
Site 26
T257
G
R
I
S
K
K
L
T
A
P
Q
K
E
L
S
Site 27
S264
T
A
P
Q
K
E
L
S
Q
V
K
V
I
D
M
Site 28
T272
Q
V
K
V
I
D
M
T
G
R
E
Q
K
V
Y
Site 29
Y279
T
G
R
E
Q
K
V
Y
Y
S
Y
S
Q
I
S
Site 30
Y280
G
R
E
Q
K
V
Y
Y
S
Y
S
Q
I
S
H
Site 31
S281
R
E
Q
K
V
Y
Y
S
Y
S
Q
I
S
H
K
Site 32
Y282
E
Q
K
V
Y
Y
S
Y
S
Q
I
S
H
K
H
Site 33
S283
Q
K
V
Y
Y
S
Y
S
Q
I
S
H
K
H
N
Site 34
S286
Y
Y
S
Y
S
Q
I
S
H
K
H
N
V
P
D
Site 35
S300
D
D
G
L
P
L
Q
S
Q
Q
L
P
Q
S
G
Site 36
S306
Q
S
Q
Q
L
P
Q
S
G
K
E
A
K
A
P
Site 37
Y344
Q
N
D
R
Q
L
Q
Y
E
R
D
M
V
V
N
Site 38
S371
D
H
E
E
R
V
I
S
N
L
S
K
V
L
E
Site 39
S392
R
R
M
Q
P
D
C
S
N
P
L
T
L
D
E
Site 40
T396
P
D
C
S
N
P
L
T
L
D
E
C
A
R
I
Site 41
Y411
F
E
T
L
Q
D
K
Y
Y
E
E
Y
R
M
S
Site 42
Y412
E
T
L
Q
D
K
Y
Y
E
E
Y
R
M
S
D
Site 43
S418
Y
Y
E
E
Y
R
M
S
D
R
V
D
L
A
V
Site 44
Y435
V
Y
P
L
M
K
E
Y
F
K
E
W
D
P
L
Site 45
Y447
D
P
L
K
D
C
T
Y
G
T
E
I
I
S
K
Site 46
S453
T
Y
G
T
E
I
I
S
K
W
K
S
L
L
E
Site 47
S457
E
I
I
S
K
W
K
S
L
L
E
N
D
Q
L
Site 48
S466
L
E
N
D
Q
L
L
S
H
G
G
Q
D
L
S
Site 49
S473
S
H
G
G
Q
D
L
S
A
D
A
F
H
R
L
Site 50
T543
V
E
N
W
N
P
L
T
D
T
V
P
I
H
S
Site 51
Y567
Q
A
R
L
E
P
L
Y
S
P
I
R
S
K
L
Site 52
S568
A
R
L
E
P
L
Y
S
P
I
R
S
K
L
S
Site 53
S572
P
L
Y
S
P
I
R
S
K
L
S
S
A
L
Q
Site 54
S576
P
I
R
S
K
L
S
S
A
L
Q
K
W
H
P
Site 55
S584
A
L
Q
K
W
H
P
S
D
S
S
A
K
L
I
Site 56
S586
Q
K
W
H
P
S
D
S
S
A
K
L
I
L
Q
Site 57
S587
K
W
H
P
S
D
S
S
A
K
L
I
L
Q
P
Site 58
T600
Q
P
W
K
D
V
F
T
P
G
S
W
E
A
F
Site 59
S603
K
D
V
F
T
P
G
S
W
E
A
F
M
V
K
Site 60
S671
Q
V
L
C
S
W
L
S
N
S
P
N
Y
E
E
Site 61
S673
L
C
S
W
L
S
N
S
P
N
Y
E
E
I
T
Site 62
Y676
W
L
S
N
S
P
N
Y
E
E
I
T
K
W
Y
Site 63
S691
L
G
W
K
S
M
F
S
D
Q
V
L
A
H
P
Site 64
S716
D
I
M
N
R
A
V
S
S
N
V
G
A
Y
M
Site 65
Y722
V
S
S
N
V
G
A
Y
M
Q
P
G
A
R
E
Site 66
Y733
G
A
R
E
N
I
A
Y
L
T
H
T
E
R
R
Site 67
T737
N
I
A
Y
L
T
H
T
E
R
R
K
D
F
Q
Site 68
Y745
E
R
R
K
D
F
Q
Y
E
A
M
Q
E
R
R
Site 69
Y802
R
H
E
G
K
Q
L
Y
T
F
G
R
I
V
I
Site 70
T803
H
E
G
K
Q
L
Y
T
F
G
R
I
V
I
Y
Site 71
T823
V
F
V
Q
G
E
K
T
W
V
P
T
S
L
Q
Site 72
S828
E
K
T
W
V
P
T
S
L
Q
S
L
I
D
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation