KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SNRK
Full Name:
SNF-related serine/threonine-protein kinase
Alias:
EC 2.7.11.1; FLJ20224; HSNFRK; KIAA0096; SNF related kinase; SNF1-related kinase
Type:
Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1;
CAMK
group; CAMKL family; SNRK subfamily
Mass (Da):
84276
Number AA:
765
UniProt ID:
Q9NRH2
International Prot ID:
IPI00470811
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0000287
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030099
GO:0006468
GO:0043523
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
A
G
F
K
R
G
Y
D
G
K
I
A
G
L
Site 2
Y16
D
G
K
I
A
G
L
Y
D
L
D
K
T
L
G
Site 3
T21
G
L
Y
D
L
D
K
T
L
G
R
G
H
F
A
Site 4
T54
I
D
K
T
K
L
D
T
L
A
T
G
H
L
F
Site 5
Y79
H
P
N
I
V
R
L
Y
E
V
I
D
T
Q
T
Site 6
Y103
D
G
G
D
M
F
D
Y
I
M
K
H
E
E
G
Site 7
Y119
N
E
D
L
A
K
K
Y
F
A
Q
I
V
H
A
Site 8
T157
K
Q
G
L
V
K
L
T
D
F
G
F
S
N
K
Site 9
S162
K
L
T
D
F
G
F
S
N
K
F
Q
P
G
K
Site 10
T172
F
Q
P
G
K
K
L
T
T
S
C
G
S
L
A
Site 11
T173
Q
P
G
K
K
L
T
T
S
C
G
S
L
A
Y
Site 12
S174
P
G
K
K
L
T
T
S
C
G
S
L
A
Y
S
Site 13
S177
K
L
T
T
S
C
G
S
L
A
Y
S
A
P
E
Site 14
S221
P
F
Q
E
A
N
D
S
E
T
L
T
M
I
M
Site 15
T223
Q
E
A
N
D
S
E
T
L
T
M
I
M
D
C
Site 16
S259
R
D
P
K
R
R
A
S
L
E
E
I
E
N
H
Site 17
S275
W
L
Q
G
V
D
P
S
P
A
T
K
Y
N
I
Site 18
T278
G
V
D
P
S
P
A
T
K
Y
N
I
P
L
V
Site 19
Y280
D
P
S
P
A
T
K
Y
N
I
P
L
V
S
Y
Site 20
S291
L
V
S
Y
K
N
L
S
E
E
E
H
N
S
I
Site 21
S297
L
S
E
E
E
H
N
S
I
I
Q
R
M
V
L
Site 22
T319
A
I
V
E
A
L
E
T
N
R
Y
N
H
I
T
Site 23
Y322
E
A
L
E
T
N
R
Y
N
H
I
T
A
T
Y
Site 24
T326
T
N
R
Y
N
H
I
T
A
T
Y
F
L
L
A
Site 25
T347
K
Q
E
K
E
I
Q
T
R
S
A
S
P
S
N
Site 26
S349
E
K
E
I
Q
T
R
S
A
S
P
S
N
I
K
Site 27
S351
E
I
Q
T
R
S
A
S
P
S
N
I
K
A
Q
Site 28
S353
Q
T
R
S
A
S
P
S
N
I
K
A
Q
F
R
Site 29
S362
I
K
A
Q
F
R
Q
S
W
P
T
K
I
D
V
Site 30
T365
Q
F
R
Q
S
W
P
T
K
I
D
V
P
Q
D
Site 31
T378
Q
D
L
E
D
D
L
T
A
T
P
L
S
H
A
Site 32
T380
L
E
D
D
L
T
A
T
P
L
S
H
A
T
V
Site 33
S383
D
L
T
A
T
P
L
S
H
A
T
V
P
Q
S
Site 34
T386
A
T
P
L
S
H
A
T
V
P
Q
S
P
A
R
Site 35
S390
S
H
A
T
V
P
Q
S
P
A
R
A
A
D
S
Site 36
S397
S
P
A
R
A
A
D
S
V
L
N
G
H
R
S
Site 37
S404
S
V
L
N
G
H
R
S
K
G
L
C
D
S
A
Site 38
S410
R
S
K
G
L
C
D
S
A
K
K
D
D
L
P
Site 39
S431
L
S
T
V
P
P
A
S
L
K
P
T
A
S
G
Site 40
T435
P
P
A
S
L
K
P
T
A
S
G
R
K
C
L
Site 41
S437
A
S
L
K
P
T
A
S
G
R
K
C
L
F
R
Site 42
S460
E
E
D
K
K
P
M
S
L
S
T
Q
V
V
L
Site 43
S462
D
K
K
P
M
S
L
S
T
Q
V
V
L
R
R
Site 44
T463
K
K
P
M
S
L
S
T
Q
V
V
L
R
R
K
Site 45
S472
V
V
L
R
R
K
P
S
V
T
N
R
L
T
S
Site 46
T474
L
R
R
K
P
S
V
T
N
R
L
T
S
R
K
Site 47
T478
P
S
V
T
N
R
L
T
S
R
K
S
A
P
V
Site 48
S479
S
V
T
N
R
L
T
S
R
K
S
A
P
V
L
Site 49
S482
N
R
L
T
S
R
K
S
A
P
V
L
N
Q
I
Site 50
S495
Q
I
F
E
E
G
E
S
D
D
E
F
D
M
D
Site 51
S510
E
N
L
P
P
K
L
S
R
L
K
M
N
I
A
Site 52
S518
R
L
K
M
N
I
A
S
P
G
T
V
H
K
R
Site 53
T521
M
N
I
A
S
P
G
T
V
H
K
R
Y
H
R
Site 54
Y526
P
G
T
V
H
K
R
Y
H
R
R
K
S
Q
G
Site 55
S531
K
R
Y
H
R
R
K
S
Q
G
R
G
S
S
C
Site 56
S536
R
K
S
Q
G
R
G
S
S
C
S
S
S
E
T
Site 57
S537
K
S
Q
G
R
G
S
S
C
S
S
S
E
T
S
Site 58
S539
Q
G
R
G
S
S
C
S
S
S
E
T
S
D
D
Site 59
S540
G
R
G
S
S
C
S
S
S
E
T
S
D
D
D
Site 60
S541
R
G
S
S
C
S
S
S
E
T
S
D
D
D
S
Site 61
T543
S
S
C
S
S
S
E
T
S
D
D
D
S
E
S
Site 62
S544
S
C
S
S
S
E
T
S
D
D
D
S
E
S
R
Site 63
S548
S
E
T
S
D
D
D
S
E
S
R
R
R
L
D
Site 64
S550
T
S
D
D
D
S
E
S
R
R
R
L
D
K
D
Site 65
S558
R
R
R
L
D
K
D
S
G
F
T
Y
S
W
H
Site 66
Y562
D
K
D
S
G
F
T
Y
S
W
H
R
R
D
S
Site 67
S563
K
D
S
G
F
T
Y
S
W
H
R
R
D
S
S
Site 68
S569
Y
S
W
H
R
R
D
S
S
E
G
P
P
G
S
Site 69
S570
S
W
H
R
R
D
S
S
E
G
P
P
G
S
E
Site 70
S576
S
S
E
G
P
P
G
S
E
G
D
G
G
G
Q
Site 71
S584
E
G
D
G
G
G
Q
S
K
P
S
N
A
S
G
Site 72
S587
G
G
G
Q
S
K
P
S
N
A
S
G
G
V
D
Site 73
S597
S
G
G
V
D
K
A
S
P
S
E
N
N
A
G
Site 74
S599
G
V
D
K
A
S
P
S
E
N
N
A
G
G
G
Site 75
S607
E
N
N
A
G
G
G
S
P
S
S
G
S
G
G
Site 76
S609
N
A
G
G
G
S
P
S
S
G
S
G
G
N
P
Site 77
S610
A
G
G
G
S
P
S
S
G
S
G
G
N
P
T
Site 78
S612
G
G
S
P
S
S
G
S
G
G
N
P
T
N
T
Site 79
T617
S
G
S
G
G
N
P
T
N
T
S
G
T
T
R
Site 80
T619
S
G
G
N
P
T
N
T
S
G
T
T
R
R
C
Site 81
T622
N
P
T
N
T
S
G
T
T
R
R
C
A
G
P
Site 82
S630
T
R
R
C
A
G
P
S
N
S
M
Q
L
A
S
Site 83
S632
R
C
A
G
P
S
N
S
M
Q
L
A
S
R
S
Site 84
S637
S
N
S
M
Q
L
A
S
R
S
A
G
E
L
V
Site 85
S639
S
M
Q
L
A
S
R
S
A
G
E
L
V
E
S
Site 86
S661
L
G
S
Q
L
H
G
S
T
K
Y
I
I
D
P
Site 87
Y664
Q
L
H
G
S
T
K
Y
I
I
D
P
Q
N
G
Site 88
S673
I
D
P
Q
N
G
L
S
F
S
S
V
K
V
Q
Site 89
S675
P
Q
N
G
L
S
F
S
S
V
K
V
Q
E
K
Site 90
S676
Q
N
G
L
S
F
S
S
V
K
V
Q
E
K
S
Site 91
T715
S
D
H
M
A
D
T
T
T
E
L
E
R
I
K
Site 92
S723
T
E
L
E
R
I
K
S
K
N
L
K
N
N
V
Site 93
T739
Q
L
P
L
C
E
K
T
I
S
V
N
I
Q
R
Site 94
S741
P
L
C
E
K
T
I
S
V
N
I
Q
R
N
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation