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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANLN
Full Name:
Actin-binding protein anillin
Alias:
Actin binding protein anillin; ANILLIN; Anillin, actin binding protein; Anln; Scra; Scraps; Scraps homolog, Drosophila; Similar to anillin, actin binding protein
Type:
Actin binding protein
Mass (Da):
124199
Number AA:
1124
UniProt ID:
Q9NQW6
International Prot ID:
IPI00657687
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005826
GO:0005634
GO:0005826
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000910
GO:0007067
GO:0007096
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T28
R
K
M
A
E
R
P
T
A
A
P
R
S
M
T
Site 2
S33
R
P
T
A
A
P
R
S
M
T
H
A
K
R
A
Site 3
T35
T
A
A
P
R
S
M
T
H
A
K
R
A
R
Q
Site 4
S45
K
R
A
R
Q
P
L
S
E
A
S
N
Q
Q
P
Site 5
S48
R
Q
P
L
S
E
A
S
N
Q
Q
P
L
S
G
Site 6
S54
A
S
N
Q
Q
P
L
S
G
G
E
E
K
S
C
Site 7
S60
L
S
G
G
E
E
K
S
C
T
K
P
S
P
S
Site 8
T62
G
G
E
E
K
S
C
T
K
P
S
P
S
K
K
Site 9
S65
E
K
S
C
T
K
P
S
P
S
K
K
R
C
S
Site 10
S67
S
C
T
K
P
S
P
S
K
K
R
C
S
D
N
Site 11
S72
S
P
S
K
K
R
C
S
D
N
T
E
V
E
V
Site 12
T75
K
K
R
C
S
D
N
T
E
V
E
V
S
N
L
Site 13
S80
D
N
T
E
V
E
V
S
N
L
E
N
K
Q
P
Site 14
S90
E
N
K
Q
P
V
E
S
T
S
A
K
S
C
S
Site 15
S92
K
Q
P
V
E
S
T
S
A
K
S
C
S
P
S
Site 16
S95
V
E
S
T
S
A
K
S
C
S
P
S
P
V
S
Site 17
S97
S
T
S
A
K
S
C
S
P
S
P
V
S
P
Q
Site 18
S99
S
A
K
S
C
S
P
S
P
V
S
P
Q
V
Q
Site 19
S102
S
C
S
P
S
P
V
S
P
Q
V
Q
P
Q
A
Site 20
S114
P
Q
A
A
D
T
I
S
D
S
V
A
V
P
A
Site 21
S132
G
M
R
R
G
L
N
S
R
L
E
A
T
A
A
Site 22
S141
L
E
A
T
A
A
S
S
V
K
T
R
M
Q
K
Site 23
T144
T
A
A
S
S
V
K
T
R
M
Q
K
L
A
E
Site 24
T162
R
W
D
N
D
D
M
T
D
D
I
P
E
S
S
Site 25
S168
M
T
D
D
I
P
E
S
S
L
F
S
P
M
P
Site 26
S169
T
D
D
I
P
E
S
S
L
F
S
P
M
P
S
Site 27
S172
I
P
E
S
S
L
F
S
P
M
P
S
E
E
K
Site 28
S176
S
L
F
S
P
M
P
S
E
E
K
A
A
S
P
Site 29
S182
P
S
E
E
K
A
A
S
P
P
R
P
L
L
S
Site 30
S189
S
P
P
R
P
L
L
S
N
A
S
A
T
P
V
Site 31
S192
R
P
L
L
S
N
A
S
A
T
P
V
G
R
R
Site 32
T194
L
L
S
N
A
S
A
T
P
V
G
R
R
G
R
Site 33
S211
N
L
A
A
T
I
C
S
W
E
D
D
V
N
H
Site 34
T232
S
V
Q
E
Q
P
G
T
A
C
L
S
K
F
S
Site 35
S236
Q
P
G
T
A
C
L
S
K
F
S
S
A
S
G
Site 36
S240
A
C
L
S
K
F
S
S
A
S
G
A
S
A
R
Site 37
S242
L
S
K
F
S
S
A
S
G
A
S
A
R
I
N
Site 38
S245
F
S
S
A
S
G
A
S
A
R
I
N
S
S
S
Site 39
S250
G
A
S
A
R
I
N
S
S
S
V
K
Q
E
A
Site 40
S251
A
S
A
R
I
N
S
S
S
V
K
Q
E
A
T
Site 41
S252
S
A
R
I
N
S
S
S
V
K
Q
E
A
T
F
Site 42
T258
S
S
V
K
Q
E
A
T
F
C
S
Q
R
D
G
Site 43
S261
K
Q
E
A
T
F
C
S
Q
R
D
G
D
A
S
Site 44
S268
S
Q
R
D
G
D
A
S
L
N
K
A
L
S
S
Site 45
S274
A
S
L
N
K
A
L
S
S
S
A
D
D
A
S
Site 46
S276
L
N
K
A
L
S
S
S
A
D
D
A
S
L
V
Site 47
S281
S
S
S
A
D
D
A
S
L
V
N
A
S
I
S
Site 48
T294
I
S
S
S
V
K
A
T
S
P
V
K
S
T
T
Site 49
S295
S
S
S
V
K
A
T
S
P
V
K
S
T
T
S
Site 50
S299
K
A
T
S
P
V
K
S
T
T
S
I
T
D
A
Site 51
S302
S
P
V
K
S
T
T
S
I
T
D
A
K
S
C
Site 52
T304
V
K
S
T
T
S
I
T
D
A
K
S
C
E
G
Site 53
S308
T
S
I
T
D
A
K
S
C
E
G
Q
N
P
E
Site 54
T320
N
P
E
L
L
P
K
T
P
I
S
P
L
K
T
Site 55
S323
L
L
P
K
T
P
I
S
P
L
K
T
G
V
S
Site 56
T327
T
P
I
S
P
L
K
T
G
V
S
K
P
I
V
Site 57
S330
S
P
L
K
T
G
V
S
K
P
I
V
K
S
T
Site 58
S336
V
S
K
P
I
V
K
S
T
L
S
Q
T
V
P
Site 59
T337
S
K
P
I
V
K
S
T
L
S
Q
T
V
P
S
Site 60
S339
P
I
V
K
S
T
L
S
Q
T
V
P
S
K
G
Site 61
T341
V
K
S
T
L
S
Q
T
V
P
S
K
G
E
L
Site 62
S349
V
P
S
K
G
E
L
S
R
E
I
C
L
Q
S
Site 63
S356
S
R
E
I
C
L
Q
S
Q
S
K
D
K
S
T
Site 64
S358
E
I
C
L
Q
S
Q
S
K
D
K
S
T
T
P
Site 65
S362
Q
S
Q
S
K
D
K
S
T
T
P
G
G
T
G
Site 66
T363
S
Q
S
K
D
K
S
T
T
P
G
G
T
G
I
Site 67
T364
Q
S
K
D
K
S
T
T
P
G
G
T
G
I
K
Site 68
T368
K
S
T
T
P
G
G
T
G
I
K
P
F
L
E
Site 69
S385
G
E
R
C
Q
E
H
S
K
E
S
P
A
R
S
Site 70
S388
C
Q
E
H
S
K
E
S
P
A
R
S
T
P
H
Site 71
S392
S
K
E
S
P
A
R
S
T
P
H
R
T
P
I
Site 72
T393
K
E
S
P
A
R
S
T
P
H
R
T
P
I
I
Site 73
T397
A
R
S
T
P
H
R
T
P
I
I
T
P
N
T
Site 74
T401
P
H
R
T
P
I
I
T
P
N
T
K
A
I
Q
Site 75
T404
T
P
I
I
T
P
N
T
K
A
I
Q
E
R
L
Site 76
T416
E
R
L
F
K
Q
D
T
S
S
S
T
T
H
L
Site 77
S417
R
L
F
K
Q
D
T
S
S
S
T
T
H
L
A
Site 78
S418
L
F
K
Q
D
T
S
S
S
T
T
H
L
A
Q
Site 79
S419
F
K
Q
D
T
S
S
S
T
T
H
L
A
Q
Q
Site 80
T421
Q
D
T
S
S
S
T
T
H
L
A
Q
Q
L
K
Site 81
S449
F
D
K
G
N
I
W
S
A
E
K
G
G
N
S
Site 82
S456
S
A
E
K
G
G
N
S
K
S
K
Q
L
E
T
Site 83
S458
E
K
G
G
N
S
K
S
K
Q
L
E
T
K
Q
Site 84
T472
Q
E
T
H
C
Q
S
T
P
L
K
K
H
Q
G
Site 85
S481
L
K
K
H
Q
G
V
S
K
T
Q
S
L
P
V
Site 86
T483
K
H
Q
G
V
S
K
T
Q
S
L
P
V
T
E
Site 87
S485
Q
G
V
S
K
T
Q
S
L
P
V
T
E
K
V
Site 88
T489
K
T
Q
S
L
P
V
T
E
K
V
T
E
N
Q
Site 89
T515
G
F
T
E
C
E
M
T
K
S
S
P
L
K
I
Site 90
S517
T
E
C
E
M
T
K
S
S
P
L
K
I
T
L
Site 91
S518
E
C
E
M
T
K
S
S
P
L
K
I
T
L
F
Site 92
S531
L
F
L
E
E
D
K
S
L
K
V
T
S
D
P
Site 93
T535
E
D
K
S
L
K
V
T
S
D
P
K
V
E
Q
Site 94
S536
D
K
S
L
K
V
T
S
D
P
K
V
E
Q
K
Site 95
S553
V
I
R
E
I
E
M
S
V
D
D
D
D
I
N
Site 96
S561
V
D
D
D
D
I
N
S
S
K
V
I
N
D
L
Site 97
S562
D
D
D
D
I
N
S
S
K
V
I
N
D
L
F
Site 98
S570
K
V
I
N
D
L
F
S
D
V
L
E
E
G
E
Site 99
S583
G
E
L
D
M
E
K
S
Q
E
E
M
D
Q
A
Site 100
S621
A
Q
T
V
G
V
V
S
P
E
S
L
V
S
T
Site 101
S624
V
G
V
V
S
P
E
S
L
V
S
T
P
R
L
Site 102
S627
V
S
P
E
S
L
V
S
T
P
R
L
E
L
K
Site 103
T628
S
P
E
S
L
V
S
T
P
R
L
E
L
K
D
Site 104
T636
P
R
L
E
L
K
D
T
S
R
S
D
E
S
P
Site 105
S637
R
L
E
L
K
D
T
S
R
S
D
E
S
P
K
Site 106
S639
E
L
K
D
T
S
R
S
D
E
S
P
K
P
G
Site 107
S642
D
T
S
R
S
D
E
S
P
K
P
G
K
F
Q
Site 108
T651
K
P
G
K
F
Q
R
T
R
V
P
R
A
E
S
Site 109
S658
T
R
V
P
R
A
E
S
G
D
S
L
G
S
E
Site 110
S661
P
R
A
E
S
G
D
S
L
G
S
E
D
R
D
Site 111
S664
E
S
G
D
S
L
G
S
E
D
R
D
L
L
Y
Site 112
Y671
S
E
D
R
D
L
L
Y
S
I
D
A
Y
R
S
Site 113
S672
E
D
R
D
L
L
Y
S
I
D
A
Y
R
S
Q
Site 114
Y676
L
L
Y
S
I
D
A
Y
R
S
Q
R
F
K
E
Site 115
S678
Y
S
I
D
A
Y
R
S
Q
R
F
K
E
T
E
Site 116
T684
R
S
Q
R
F
K
E
T
E
R
P
S
I
K
Q
Site 117
S688
F
K
E
T
E
R
P
S
I
K
Q
V
I
V
R
Site 118
T700
I
V
R
K
E
D
V
T
S
K
L
D
E
K
N
Site 119
S701
V
R
K
E
D
V
T
S
K
L
D
E
K
N
N
Site 120
T767
E
R
L
L
L
I
A
T
G
K
R
T
L
L
I
Site 121
T771
L
I
A
T
G
K
R
T
L
L
I
D
E
L
N
Site 122
S792
P
Q
R
K
N
K
A
S
P
Q
S
E
F
M
P
Site 123
S795
K
N
K
A
S
P
Q
S
E
F
M
P
S
K
G
Site 124
S800
P
Q
S
E
F
M
P
S
K
G
S
V
T
L
S
Site 125
S803
E
F
M
P
S
K
G
S
V
T
L
S
E
I
R
Site 126
S807
S
K
G
S
V
T
L
S
E
I
R
L
P
L
K
Site 127
T846
G
A
E
N
M
V
A
T
P
L
A
S
T
S
N
Site 128
S852
A
T
P
L
A
S
T
S
N
S
L
N
G
D
A
Site 129
S854
P
L
A
S
T
S
N
S
L
N
G
D
A
L
T
Site 130
T863
N
G
D
A
L
T
F
T
T
T
F
T
L
Q
D
Site 131
T867
L
T
F
T
T
T
F
T
L
Q
D
V
S
N
D
Site 132
S902
K
K
K
K
T
S
K
S
K
A
I
T
P
K
R
Site 133
T906
T
S
K
S
K
A
I
T
P
K
R
L
L
T
S
Site 134
T912
I
T
P
K
R
L
L
T
S
I
T
T
K
S
N
Site 135
T915
K
R
L
L
T
S
I
T
T
K
S
N
I
H
S
Site 136
T916
R
L
L
T
S
I
T
T
K
S
N
I
H
S
S
Site 137
S918
L
T
S
I
T
T
K
S
N
I
H
S
S
V
M
Site 138
S922
T
T
K
S
N
I
H
S
S
V
M
A
S
P
G
Site 139
S923
T
K
S
N
I
H
S
S
V
M
A
S
P
G
G
Site 140
S927
I
H
S
S
V
M
A
S
P
G
G
L
S
A
V
Site 141
S932
M
A
S
P
G
G
L
S
A
V
R
T
S
N
F
Site 142
S950
G
S
Y
T
L
S
L
S
S
V
G
N
T
K
F
Site 143
Y973
S
S
L
E
G
H
I
Y
L
K
I
K
C
Q
V
Site 144
S983
I
K
C
Q
V
N
S
S
V
E
E
R
G
F
L
Site 145
Y1019
N
C
I
S
Y
W
T
Y
P
D
D
E
K
R
K
Site 146
S1039
I
N
L
A
N
C
T
S
R
Q
I
E
P
A
N
Site 147
T1055
E
F
C
A
R
R
N
T
F
E
L
I
T
V
R
Site 148
T1060
R
N
T
F
E
L
I
T
V
R
P
Q
R
E
D
Site 149
T1071
Q
R
E
D
D
R
E
T
L
V
S
Q
C
R
D
Site 150
S1074
D
D
R
E
T
L
V
S
Q
C
R
D
T
L
C
Site 151
S1088
C
V
T
K
N
W
L
S
A
D
T
K
E
E
R
Site 152
Y1118
L
W
Q
P
D
A
C
Y
K
P
I
G
K
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation