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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TSAd
Full Name:
SH2 domain-containing protein 2A
Alias:
F2771; SCAP; SH2 domain containing adapter; SH2 domain protein 2A; SH2 domain-containing 2A; SH22A; SH2A; SH2D2A; T cell specific adapter protein TSAd; T cell specific adpater protein TSAd; T cell-specific adapter; T lymphocyte specific adaptor protein; VEGF receptor-associated; VRAP
Type:
Adapter/scaffold protein
Mass (Da):
42934
Number AA:
389
UniProt ID:
Q9NP31
International Prot ID:
IPI00099806
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005625
Uniprot
OncoNet
Molecular Function:
GO:0017124
GO:0005070
PhosphoSite+
KinaseNET
Biological Process:
GO:0001525
GO:0030154
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
S
H
E
A
P
I
P
T
F
S
T
F
Q
I
T
Site 2
Y39
R
S
C
Q
N
L
G
Y
T
A
A
S
P
Q
A
Site 3
S43
N
L
G
Y
T
A
A
S
P
Q
A
P
E
A
A
Site 4
Y117
E
P
K
P
Q
G
C
Y
L
V
R
F
S
E
S
Site 5
T127
R
F
S
E
S
A
V
T
F
V
L
T
Y
R
S
Site 6
T171
Q
D
L
L
L
H
Y
T
A
H
P
L
S
P
Y
Site 7
S176
H
Y
T
A
H
P
L
S
P
Y
G
E
T
L
T
Site 8
Y178
T
A
H
P
L
S
P
Y
G
E
T
L
T
E
P
Site 9
T190
T
E
P
L
A
R
Q
T
P
E
P
A
G
L
S
Site 10
S197
T
P
E
P
A
G
L
S
L
R
T
E
E
S
N
Site 11
S203
L
S
L
R
T
E
E
S
N
F
G
S
K
S
Q
Site 12
S207
T
E
E
S
N
F
G
S
K
S
Q
D
P
N
P
Site 13
S209
E
S
N
F
G
S
K
S
Q
D
P
N
P
Q
Y
Site 14
Y216
S
Q
D
P
N
P
Q
Y
S
P
I
I
K
Q
G
Site 15
S217
Q
D
P
N
P
Q
Y
S
P
I
I
K
Q
G
Q
Site 16
S240
G
A
G
E
K
E
P
S
Q
L
L
R
P
K
P
Site 17
Y260
P
Q
L
P
P
E
V
Y
T
I
P
V
P
R
H
Site 18
T261
Q
L
P
P
E
V
Y
T
I
P
V
P
R
H
R
Site 19
S276
P
A
P
R
P
K
P
S
N
P
I
Y
N
E
P
Site 20
Y280
P
K
P
S
N
P
I
Y
N
E
P
D
E
P
I
Site 21
Y290
P
D
E
P
I
A
F
Y
A
M
G
R
G
S
P
Site 22
S296
F
Y
A
M
G
R
G
S
P
G
E
A
P
S
N
Site 23
S302
G
S
P
G
E
A
P
S
N
I
Y
V
E
V
E
Site 24
Y305
G
E
A
P
S
N
I
Y
V
E
V
E
D
E
G
Site 25
T316
E
D
E
G
L
P
A
T
L
G
H
P
V
L
R
Site 26
S325
G
H
P
V
L
R
K
S
W
S
R
P
V
P
G
Site 27
S327
P
V
L
R
K
S
W
S
R
P
V
P
G
G
Q
Site 28
T336
P
V
P
G
G
Q
N
T
G
G
S
Q
L
H
S
Site 29
S339
G
G
Q
N
T
G
G
S
Q
L
H
S
E
N
S
Site 30
S343
T
G
G
S
Q
L
H
S
E
N
S
V
I
G
Q
Site 31
S346
S
Q
L
H
S
E
N
S
V
I
G
Q
G
P
P
Site 32
T365
P
P
P
A
W
R
H
T
L
P
H
N
L
S
R
Site 33
S371
H
T
L
P
H
N
L
S
R
Q
V
L
Q
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation