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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FANCE
Full Name:
Fanconi anemia group E protein
Alias:
FACE; FAE; Fanconi anemia, complementation group E
Type:
DNA repair
Mass (Da):
58711
Number AA:
536
UniProt ID:
Q9HB96
International Prot ID:
IPI00030252
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
G
V
L
R
A
L
G
S
R
G
W
E
P
F
D
Site 2
S149
R
D
L
G
V
G
T
S
M
E
G
A
S
P
L
Site 3
S154
G
T
S
M
E
G
A
S
P
L
S
E
R
C
Q
Site 4
S157
M
E
G
A
S
P
L
S
E
R
C
Q
R
Q
L
Site 5
S166
R
C
Q
R
Q
L
Q
S
L
C
R
G
L
G
L
Site 6
S180
L
G
G
R
R
L
K
S
P
Q
A
P
D
P
E
Site 7
S194
E
E
E
E
N
R
D
S
Q
Q
P
G
K
R
R
Site 8
S204
P
G
K
R
R
K
D
S
E
E
E
A
A
S
P
Site 9
S210
D
S
E
E
E
A
A
S
P
E
G
K
R
V
P
Site 10
S238
K
E
R
P
E
H
K
S
L
E
S
L
A
D
G
Site 11
S241
P
E
H
K
S
L
E
S
L
A
D
G
G
S
A
Site 12
S247
E
S
L
A
D
G
G
S
A
S
P
I
K
D
Q
Site 13
S249
L
A
D
G
G
S
A
S
P
I
K
D
Q
P
V
Site 14
T261
Q
P
V
M
A
V
K
T
G
E
D
G
S
N
L
Site 15
S266
V
K
T
G
E
D
G
S
N
L
D
D
A
K
G
Site 16
T297
R
L
Q
Q
L
L
K
T
L
E
E
G
L
E
G
Site 17
T346
L
G
L
L
R
L
C
T
W
L
L
A
L
S
P
Site 18
S366
N
A
T
V
L
T
R
S
L
F
L
G
R
I
L
Site 19
S374
L
F
L
G
R
I
L
S
L
T
S
S
A
S
R
Site 20
S378
R
I
L
S
L
T
S
S
A
S
R
L
L
T
T
Site 21
T412
P
V
L
Q
A
P
G
T
G
P
A
Q
T
E
L
Site 22
T450
E
L
P
W
K
E
E
T
F
L
V
L
Q
S
L
Site 23
T465
L
E
R
Q
V
E
M
T
P
E
K
F
S
V
L
Site 24
Y489
A
A
T
T
S
M
A
Y
A
K
L
M
L
T
V
Site 25
Y500
M
L
T
V
M
T
K
Y
Q
A
N
I
T
E
T
Site 26
T507
Y
Q
A
N
I
T
E
T
Q
R
L
G
L
A
M
Site 27
T521
M
A
L
E
P
N
T
T
F
L
R
K
S
L
K
Site 28
S526
N
T
T
F
L
R
K
S
L
K
A
A
L
K
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation