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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
POLDIP3
Full Name:
Polymerase delta-interacting protein 3
Alias:
46 kDa DNA polymerase delta interaction protein; KIAA1649; P46; PDIP3; PDIP46; PDP3; Polymerase (DNA-directed) delta interacting protein 3; Polymerase delta interacting protein 3; Polymerase delta-interacting protein 3: 46 kDa DNA polymerase delta interaction protein: p46: Polymerase delta-interacting protein 3: 46 kDa DNA polymerase delta interaction protein: p46: Putative uncharacterized protein DKFZp434G0310: POLDIP3 protein: Polymerase delta interacting protein 46
Type:
RNA binding protein
Mass (Da):
46089
Number AA:
421
UniProt ID:
Q9BY77
International Prot ID:
IPI00440688
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
D
I
S
L
D
E
L
I
R
K
Site 2
S32
P
G
V
G
G
V
R
S
R
V
G
I
Q
Q
G
Site 3
S42
G
I
Q
Q
G
L
L
S
Q
S
T
R
T
A
T
Site 4
S44
Q
Q
G
L
L
S
Q
S
T
R
T
A
T
F
Q
Site 5
T49
S
Q
S
T
R
T
A
T
F
Q
Q
R
F
D
A
Site 6
S63
A
R
Q
K
I
G
L
S
D
A
R
L
K
L
G
Site 7
S100
D
A
R
E
M
L
N
S
R
K
Q
Q
T
T
V
Site 8
T105
L
N
S
R
K
Q
Q
T
T
V
P
Q
K
P
R
Site 9
T106
N
S
R
K
Q
Q
T
T
V
P
Q
K
P
R
Q
Site 10
S122
A
D
A
R
E
K
I
S
L
K
R
S
S
P
A
Site 11
S126
E
K
I
S
L
K
R
S
S
P
A
A
F
I
N
Site 12
S127
K
I
S
L
K
R
S
S
P
A
A
F
I
N
P
Site 13
T140
N
P
P
I
G
T
V
T
P
A
L
K
L
T
K
Site 14
T148
P
A
L
K
L
T
K
T
I
Q
V
P
Q
Q
K
Site 15
Y182
H
Q
A
K
Q
N
L
Y
D
L
D
E
D
D
D
Site 16
S193
E
D
D
D
G
I
A
S
V
P
T
K
Q
M
K
Site 17
S215
L
H
H
M
A
G
L
S
S
S
K
L
S
M
S
Site 18
S216
H
H
M
A
G
L
S
S
S
K
L
S
M
S
K
Site 19
S217
H
M
A
G
L
S
S
S
K
L
S
M
S
K
A
Site 20
S222
S
S
S
K
L
S
M
S
K
A
L
P
L
T
K
Site 21
T228
M
S
K
A
L
P
L
T
K
V
V
Q
N
D
A
Site 22
Y236
K
V
V
Q
N
D
A
Y
T
A
P
A
L
P
S
Site 23
T237
V
V
Q
N
D
A
Y
T
A
P
A
L
P
S
S
Site 24
T247
A
L
P
S
S
I
R
T
K
A
L
T
N
M
S
Site 25
T251
S
I
R
T
K
A
L
T
N
M
S
R
T
L
V
Site 26
S275
P
A
A
E
P
V
L
S
P
L
E
G
T
K
M
Site 27
T283
P
L
E
G
T
K
M
T
V
N
N
L
H
P
R
Site 28
T292
N
N
L
H
P
R
V
T
E
E
D
I
V
E
L
Site 29
T329
V
K
K
D
D
A
I
T
A
Y
K
K
Y
N
N
Site 30
Y334
A
I
T
A
Y
K
K
Y
N
N
R
C
L
D
G
Site 31
S366
Q
P
I
L
L
R
L
S
D
S
P
S
M
K
K
Site 32
S368
I
L
L
R
L
S
D
S
P
S
M
K
K
E
S
Site 33
S370
L
R
L
S
D
S
P
S
M
K
K
E
S
E
L
Site 34
S383
E
L
P
R
R
V
N
S
A
S
S
S
N
P
P
Site 35
S385
P
R
R
V
N
S
A
S
S
S
N
P
P
A
E
Site 36
S387
R
V
N
S
A
S
S
S
N
P
P
A
E
V
D
Site 37
T397
P
A
E
V
D
P
D
T
I
L
K
A
L
F
K
Site 38
S405
I
L
K
A
L
F
K
S
S
G
A
S
V
T
T
Site 39
S406
L
K
A
L
F
K
S
S
G
A
S
V
T
T
Q
Site 40
S409
L
F
K
S
S
G
A
S
V
T
T
Q
P
T
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation