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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PINK1
Full Name:
Serine/threonine-protein kinase PINK1, mitochondrial
Alias:
BRPK;PTEN-induced putative kinase protein 1
Type:
Mass (Da):
62769
Number AA:
581
UniProt ID:
Q9BXM7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Serine/threonine-protein kinase PINK1, mitochondrial (PTEN-induced putative kinase protein 1) pan-specific antibody AB-NK304-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NK304-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
R
A
L
L
L
R
F
T
G
K
P
G
R
A
Y
Site 2
Y29
T
G
K
P
G
R
A
Y
G
L
G
R
P
G
P
Site 3
S73
R
L
R
F
F
R
Q
S
V
A
G
L
A
A
R
Site 4
S118
I
E
E
K
Q
A
E
S
R
R
A
V
S
A
C
Site 5
S123
A
E
S
R
R
A
V
S
A
C
Q
E
I
Q
A
Site 6
S136
Q
A
I
F
T
Q
K
S
K
P
G
P
D
P
L
Site 7
T145
P
G
P
D
P
L
D
T
R
R
L
Q
G
F
R
Site 8
Y156
Q
G
F
R
L
E
E
Y
L
I
G
Q
S
I
G
Site 9
S187
Q
N
L
E
V
T
K
S
T
G
L
L
P
G
R
Site 10
T198
L
P
G
R
G
P
G
T
S
A
P
G
E
G
Q
Site 11
S199
P
G
R
G
P
G
T
S
A
P
G
E
G
Q
E
Site 12
S225
I
K
M
M
W
N
I
S
A
G
S
S
S
E
A
Site 13
S228
M
W
N
I
S
A
G
S
S
S
E
A
I
L
N
Site 14
S229
W
N
I
S
A
G
S
S
S
E
A
I
L
N
T
Site 15
S230
N
I
S
A
G
S
S
S
E
A
I
L
N
T
M
Site 16
T236
S
S
E
A
I
L
N
T
M
S
Q
E
L
V
P
Site 17
T257
A
G
E
Y
G
A
V
T
Y
R
K
S
K
R
G
Site 18
S261
G
A
V
T
Y
R
K
S
K
R
G
P
K
Q
L
Site 19
T313
E
G
L
G
H
G
R
T
L
F
L
V
M
K
N
Site 20
Y328
Y
P
C
T
L
R
Q
Y
L
C
V
N
T
P
S
Site 21
T333
R
Q
Y
L
C
V
N
T
P
S
P
R
L
A
A
Site 22
S365
I
A
H
R
D
L
K
S
D
N
I
L
V
E
L
Site 23
S401
I
G
L
Q
L
P
F
S
S
W
Y
V
D
R
G
Site 24
S402
G
L
Q
L
P
F
S
S
W
Y
V
D
R
G
G
Site 25
Y404
Q
L
P
F
S
S
W
Y
V
D
R
G
G
N
G
Site 26
Y431
G
P
R
A
V
I
D
Y
S
K
A
D
A
W
A
Site 27
S432
P
R
A
V
I
D
Y
S
K
A
D
A
W
A
V
Site 28
Y466
A
H
L
E
S
R
S
Y
Q
E
A
Q
L
P
A
Site 29
S477
Q
L
P
A
L
P
E
S
V
P
P
D
V
R
Q
Site 30
S495
A
L
L
Q
R
E
A
S
K
R
P
S
A
R
V
Site 31
S499
R
E
A
S
K
R
P
S
A
R
V
A
A
N
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation