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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDX2
Full Name:
Homeobox protein CDX-2
Alias:
CDX-3;Caudal-type homeobox protein 2
Type:
Transcription protein
Mass (Da):
33510
Number AA:
313
UniProt ID:
Q99626
International Prot ID:
IPI00016928
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0009887
GO:0006366
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
Y
L
L
D
K
D
V
S
M
Y
P
S
S
V
R
Site 2
Y14
L
D
K
D
V
S
M
Y
P
S
S
V
R
H
S
Site 3
S16
K
D
V
S
M
Y
P
S
S
V
R
H
S
G
G
Site 4
S17
D
V
S
M
Y
P
S
S
V
R
H
S
G
G
L
Site 5
S21
Y
P
S
S
V
R
H
S
G
G
L
N
L
A
P
Site 6
S33
L
A
P
Q
N
F
V
S
P
P
Q
Y
P
D
Y
Site 7
Y37
N
F
V
S
P
P
Q
Y
P
D
Y
G
G
Y
H
Site 8
Y40
S
P
P
Q
Y
P
D
Y
G
G
Y
H
V
A
A
Site 9
S57
A
A
A
A
N
L
D
S
A
Q
S
P
G
P
S
Site 10
S60
A
N
L
D
S
A
Q
S
P
G
P
S
W
P
A
Site 11
S64
S
A
Q
S
P
G
P
S
W
P
A
A
Y
G
A
Site 12
Y69
G
P
S
W
P
A
A
Y
G
A
P
L
R
E
D
Site 13
S100
A
H
G
L
N
G
G
S
P
A
A
A
M
G
Y
Site 14
Y107
S
P
A
A
A
M
G
Y
S
S
P
A
D
Y
H
Site 15
S109
A
A
A
M
G
Y
S
S
P
A
D
Y
H
P
H
Site 16
Y113
G
Y
S
S
P
A
D
Y
H
P
H
H
H
P
H
Site 17
T139
C
A
S
G
L
L
Q
T
L
N
P
G
P
P
G
Site 18
S157
T
A
A
A
E
Q
L
S
P
G
G
Q
R
R
N
Site 19
S179
P
A
Q
Q
S
L
G
S
Q
V
K
T
R
T
K
Site 20
T183
S
L
G
S
Q
V
K
T
R
T
K
D
K
Y
R
Site 21
Y189
K
T
R
T
K
D
K
Y
R
V
V
Y
T
D
H
Site 22
Y193
K
D
K
Y
R
V
V
Y
T
D
H
Q
R
L
E
Site 23
Y207
E
L
E
K
E
F
H
Y
S
R
Y
I
T
I
R
Site 24
T212
F
H
Y
S
R
Y
I
T
I
R
R
K
A
E
L
Site 25
T222
R
K
A
E
L
A
A
T
L
G
L
S
E
R
Q
Site 26
S226
L
A
A
T
L
G
L
S
E
R
Q
V
K
I
W
Site 27
S277
P
Q
P
G
P
L
R
S
V
P
E
P
L
S
P
Site 28
S283
R
S
V
P
E
P
L
S
P
V
S
S
L
Q
A
Site 29
S286
P
E
P
L
S
P
V
S
S
L
Q
A
S
V
S
Site 30
S287
E
P
L
S
P
V
S
S
L
Q
A
S
V
S
G
Site 31
T310
T
G
G
V
L
N
P
T
V
T
Q
_
_
_
_
Site 32
T312
G
V
L
N
P
T
V
T
Q
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation