PhosphoNET

           
Protein Info 
   
Short Name:  CENTG1
Full Name:  Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
Alias:  AGAP-2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; CEG1; CENG1; Centaurin-gamma 1; Centaurin-gamma-1; GGAP2; GTP-binding and GTPase-activating protein 2; KIAA0167; Phosphatidylinositol-3-kinase enhancer; PIKE-A
Type:  GTPase activating protein, ARF
Mass (Da):  124674
Number AA:  1192
UniProt ID:  Q99490
International Prot ID:  IPI00015401
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0008060  GO:0005525  GO:0003924 PhosphoSite+ KinaseNET
Biological Process:  GO:0015031  GO:0032312  GO:0007264 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T13GALQRRTTTYLISLT
Site 2S26LTLVKLESVPPPPPS
Site 3S33SVPPPPPSPSAAAVG
Site 4S35PPPPPSPSAAAVGAP
Site 5S47GAPGARGSEPRDPGS
Site 6S54SEPRDPGSPRGAEEP
Site 7S79RQDALWISTSSAGAG
Site 8S94GAEPPALSPAPASPA
Site 9S99ALSPAPASPARPVSP
Site 10S105ASPARPVSPAPGRRL
Site 11S113PAPGRRLSLWAAPPG
Site 12S124APPGPPLSGGLSPDS
Site 13S128PPLSGGLSPDSKPGG
Site 14S131SGGLSPDSKPGGAPS
Site 15S138SKPGGAPSSSRRPLL
Site 16S139KPGGAPSSSRRPLLS
Site 17S140PGGAPSSSRRPLLSS
Site 18S146SSRRPLLSSPSWGGP
Site 19S147SRRPLLSSPSWGGPE
Site 20S149RPLLSSPSWGGPEPE
Site 21S166TGGGVPGSSSPHPGT
Site 22S167GGGVPGSSSPHPGTG
Site 23S168GGVPGSSSPHPGTGS
Site 24T173SSSPHPGTGSRRLKV
Site 25S175SPHPGTGSRRLKVAP
Site 26T192PAPKPCKTVTTSGAK
Site 27T194PKPCKTVTTSGAKAG
Site 28S196PCKTVTTSGAKAGGG
Site 29S208GGGKGAGSRLSWPES
Site 30S211KGAGSRLSWPESEGK
Site 31S215SRLSWPESEGKPRVK
Site 32S224GKPRVKGSKSSAGTG
Site 33S226PRVKGSKSSAGTGAS
Site 34T230GSKSSAGTGASVSAA
Site 35S248AAAGGGGSTASTSGG
Site 36S251GGGGSTASTSGGVGA
Site 37T252GGGSTASTSGGVGAG
Site 38S267AGARGKLSPRKGKSK
Site 39S273LSPRKGKSKTLDNSD
Site 40T275PRKGKSKTLDNSDLH
Site 41S289HPGPPAGSPPPLTLP
Site 42T294AGSPPPLTLPPTPSP
Site 43T320PGPAPPITLEPPAPG
Site 44S338GREGGRASTRDRKML
Site 45T339REGGRASTRDRKMLK
Site 46S349RKMLKFISGIFTKST
Site 47T353KFISGIFTKSTGGPP
Site 48S355ISGIFTKSTGGPPGS
Site 49T356SGIFTKSTGGPPGSG
Site 50S362STGGPPGSGPLPGPP
Site 51S370GPLPGPPSLSSGSGS
Site 52S372LPGPPSLSSGSGSRE
Site 53S373PGPPSLSSGSGSREL
Site 54S375PPSLSSGSGSRELLG
Site 55S377SLSSGSGSRELLGAE
Site 56S388LGAELRASPKAVINS
Site 57S395SPKAVINSQEWTLSR
Site 58T399VINSQEWTLSRSIPE
Site 59S401NSQEWTLSRSIPELR
Site 60S403QEWTLSRSIPELRLG
Site 61S417GVLGDARSGKSSLIH
Site 62S421DARSGKSSLIHRFLT
Site 63S430IHRFLTGSYQVLEKT
Site 64Y431HRFLTGSYQVLEKTE
Site 65T437SYQVLEKTESEQYKK
Site 66S439QVLEKTESEQYKKEM
Site 67Y442EKTESEQYKKEMLVD
Site 68S486FSLEDENSFQAVSRL
Site 69S498SRLHGQLSSLRGEGR
Site 70S499RLHGQLSSLRGEGRG
Site 71T515LALALVGTQDRISAS
Site 72S520VGTQDRISASSPRVV
Site 73S522TQDRISASSPRVVGD
Site 74S523QDRISASSPRVVGDA
Site 75Y544ADMKRCSYYETCATY
Site 76Y545DMKRCSYYETCATYG
Site 77T568EVAQKVVTLRKQQQL
Site 78S581QLLAACKSLPSSPSH
Site 79S584AACKSLPSSPSHSAA
Site 80S585ACKSLPSSPSHSAAS
Site 81S587KSLPSSPSHSAASTP
Site 82S589LPSSPSHSAASTPVA
Site 83S592SPSHSAASTPVAGQA
Site 84T593PSHSAASTPVAGQAS
Site 85S600TPVAGQASNGGHTSD
Site 86T605QASNGGHTSDYSSSL
Site 87S606ASNGGHTSDYSSSLP
Site 88Y608NGGHTSDYSSSLPSS
Site 89S609GGHTSDYSSSLPSSP
Site 90S610GHTSDYSSSLPSSPN
Site 91S611HTSDYSSSLPSSPNV
Site 92S614DYSSSLPSSPNVGHR
Site 93S615YSSSLPSSPNVGHRE
Site 94S634AAAVAGLSTPGSLHR
Site 95T635AAVAGLSTPGSLHRA
Site 96S638AGLSTPGSLHRAAKR
Site 97T647HRAAKRRTSLFANRR
Site 98S648RAAKRRTSLFANRRG
Site 99S656LFANRRGSDSEKRSL
Site 100S658ANRRGSDSEKRSLDS
Site 101S662GSDSEKRSLDSRGET
Site 102T669SLDSRGETTGSGRAI
Site 103S672SRGETTGSGRAIPIK
Site 104S681RAIPIKQSFLLKRSG
Site 105S687QSFLLKRSGNSLNKE
Site 106Y699NKEWKKKYVTLSSNG
Site 107T701EWKKKYVTLSSNGFL
Site 108S703KKKYVTLSSNGFLLY
Site 109Y710SSNGFLLYHPSINDY
Site 110Y717YHPSINDYIHSTHGK
Site 111T732EMDLLRTTVKVPGKR
Site 112S745KRPPRAISAFGPSAS
Site 113S750AISAFGPSASINGLV
Site 114S752SAFGPSASINGLVKD
Site 115S761NGLVKDMSTVQMGEG
Site 116T773GEGLEATTPMPSPSP
Site 117S777EATTPMPSPSPSPSS
Site 118S779TTPMPSPSPSPSSLQ
Site 119S781PMPSPSPSPSSLQPP
Site 120S783PSPSPSPSSLQPPPD
Site 121S784SPSPSPSSLQPPPDQ
Site 122S808RNLARALSTDCTPSG
Site 123T809NLARALSTDCTPSGD
Site 124T812RALSTDCTPSGDLSP
Site 125S814LSTDCTPSGDLSPLS
Site 126S818CTPSGDLSPLSREPP
Site 127S821SGDLSPLSREPPPSP
Site 128S827LSREPPPSPMVKKQR
Site 129T839KQRRKKLTTPSKTEG
Site 130T840QRRKKLTTPSKTEGS
Site 131S842RKKLTTPSKTEGSAG
Site 132S862RKMWKLKSFGSLRNI
Site 133S865WKLKSFGSLRNIYKA
Site 134Y870FGSLRNIYKAEENFE
Site 135S918ASLQCCESSKVKLRT
Site 136T925SSKVKLRTDSQSEAV
Site 137S927KVKLRTDSQSEAVAI
Site 138S929KLRTDSQSEAVAIQA
Site 139S981RNLGTHLSRVRSLDL
Site 140S985THLSRVRSLDLDDWP
Site 141T1006LTAIGNDTANRVWES
Site 142S1013TANRVWESDTRGRAK
Site 143S1022TRGRAKPSRDSSREE
Site 144S1025RAKPSRDSSREERES
Site 145S1026AKPSRDSSREERESW
Site 146S1032SSREERESWIRAKYE
Site 147Y1038ESWIRAKYEQLLFLA
Site 148S1050FLAPLSTSEEPLGRQ
Site 149T1084ARHGPLDTSVEDPQL
Site 150S1085RHGPLDTSVEDPQLR
Site 151S1093VEDPQLRSPLHLAAE
Site 152Y1130QGRTALFYARQAGSQ
Site 153S1154GCPGEGGSAATTPSA
Site 154T1158EGGSAATTPSAATTP
Site 155S1160GSAATTPSAATTPSI
Site 156T1164TTPSAATTPSITATP
Site 157S1166PSAATTPSITATPSP
Site 158T1168AATTPSITATPSPRR
Site 159T1170TTPSITATPSPRRRS
Site 160S1172PSITATPSPRRRSSA
Site 161S1177TPSPRRRSSAASVGR
Site 162S1178PSPRRRSSAASVGRA
Site 163S1181RRRSSAASVGRADAP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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