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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDC5L
Full Name:
Cell division cycle 5-like protein
Alias:
CDC5; CDC5 cell division cycle 5-like; Cdc5-like protein; CDC5-related protein; CEF1; Cell division cycle 5, S. pombe, homolog; PCDC5RP; Pombe cdc5-related protein
Type:
Transcription factor; RNA processing
Mass (Da):
92251
Number AA:
802
UniProt ID:
Q99459
International Prot ID:
IPI00465294
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016607
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003723
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0007049
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
K
G
G
V
W
R
N
T
E
D
E
I
L
K
A
Site 2
Y26
L
K
A
A
V
M
K
Y
G
K
N
Q
W
S
R
Site 3
S32
K
Y
G
K
N
Q
W
S
R
I
A
S
L
L
H
Site 4
S36
N
Q
W
S
R
I
A
S
L
L
H
R
K
S
A
Site 5
S42
A
S
L
L
H
R
K
S
A
K
Q
C
K
A
R
Site 6
Y51
K
Q
C
K
A
R
W
Y
E
W
L
D
P
S
I
Site 7
T61
L
D
P
S
I
K
K
T
E
W
S
R
E
E
E
Site 8
S64
S
I
K
K
T
E
W
S
R
E
E
E
E
K
L
Site 9
T117
R
D
N
E
E
E
T
T
D
D
P
R
K
L
K
Site 10
T134
E
I
D
P
N
P
E
T
K
P
A
R
P
D
P
Site 11
Y210
K
R
K
R
G
V
D
Y
N
A
E
I
P
F
E
Site 12
Y225
K
K
P
A
L
G
F
Y
D
T
S
E
E
N
Y
Site 13
T227
P
A
L
G
F
Y
D
T
S
E
E
N
Y
Q
A
Site 14
S228
A
L
G
F
Y
D
T
S
E
E
N
Y
Q
A
L
Site 15
Y232
Y
D
T
S
E
E
N
Y
Q
A
L
D
A
D
F
Site 16
S277
K
K
E
S
D
L
P
S
A
I
L
Q
T
S
G
Site 17
S283
P
S
A
I
L
Q
T
S
G
V
S
E
F
T
K
Site 18
S303
V
L
P
A
P
Q
I
S
D
A
E
L
Q
E
V
Site 19
S317
V
V
K
V
G
Q
A
S
E
I
A
R
Q
T
A
Site 20
T323
A
S
E
I
A
R
Q
T
A
E
E
S
G
I
T
Site 21
S327
A
R
Q
T
A
E
E
S
G
I
T
N
S
A
S
Site 22
T330
T
A
E
E
S
G
I
T
N
S
A
S
S
T
L
Site 23
S332
E
E
S
G
I
T
N
S
A
S
S
T
L
L
S
Site 24
S334
S
G
I
T
N
S
A
S
S
T
L
L
S
E
Y
Site 25
S335
G
I
T
N
S
A
S
S
T
L
L
S
E
Y
N
Site 26
T336
I
T
N
S
A
S
S
T
L
L
S
E
Y
N
V
Site 27
S339
S
A
S
S
T
L
L
S
E
Y
N
V
T
N
N
Site 28
Y341
S
S
T
L
L
S
E
Y
N
V
T
N
N
S
V
Site 29
T344
L
L
S
E
Y
N
V
T
N
N
S
V
A
L
R
Site 30
S347
E
Y
N
V
T
N
N
S
V
A
L
R
T
P
R
Site 31
T352
N
N
S
V
A
L
R
T
P
R
T
P
A
S
Q
Site 32
T355
V
A
L
R
T
P
R
T
P
A
S
Q
D
R
I
Site 33
S358
R
T
P
R
T
P
A
S
Q
D
R
I
L
Q
E
Site 34
T373
A
Q
N
L
M
A
L
T
N
V
D
T
P
L
K
Site 35
T377
M
A
L
T
N
V
D
T
P
L
K
G
G
L
N
Site 36
T385
P
L
K
G
G
L
N
T
P
L
H
E
S
D
F
Site 37
S390
L
N
T
P
L
H
E
S
D
F
S
G
V
T
P
Site 38
S393
P
L
H
E
S
D
F
S
G
V
T
P
Q
R
Q
Site 39
T396
E
S
D
F
S
G
V
T
P
Q
R
Q
V
V
Q
Site 40
T404
P
Q
R
Q
V
V
Q
T
P
N
T
V
L
S
T
Site 41
T407
Q
V
V
Q
T
P
N
T
V
L
S
T
P
F
R
Site 42
S410
Q
T
P
N
T
V
L
S
T
P
F
R
T
P
S
Site 43
T411
T
P
N
T
V
L
S
T
P
F
R
T
P
S
N
Site 44
T415
V
L
S
T
P
F
R
T
P
S
N
G
A
E
G
Site 45
S417
S
T
P
F
R
T
P
S
N
G
A
E
G
L
T
Site 46
T424
S
N
G
A
E
G
L
T
P
R
S
G
T
T
P
Site 47
S427
A
E
G
L
T
P
R
S
G
T
T
P
K
P
V
Site 48
T429
G
L
T
P
R
S
G
T
T
P
K
P
V
I
N
Site 49
T430
L
T
P
R
S
G
T
T
P
K
P
V
I
N
S
Site 50
S437
T
P
K
P
V
I
N
S
T
P
G
R
T
P
L
Site 51
T438
P
K
P
V
I
N
S
T
P
G
R
T
P
L
R
Site 52
T442
I
N
S
T
P
G
R
T
P
L
R
D
K
L
N
Site 53
Y459
P
E
D
G
M
A
D
Y
S
D
P
S
Y
V
K
Site 54
S460
E
D
G
M
A
D
Y
S
D
P
S
Y
V
K
Q
Site 55
S463
M
A
D
Y
S
D
P
S
Y
V
K
Q
M
E
R
Site 56
Y464
A
D
Y
S
D
P
S
Y
V
K
Q
M
E
R
E
Site 57
S472
V
K
Q
M
E
R
E
S
R
E
H
L
R
L
G
Site 58
T510
E
E
R
E
I
D
D
T
Y
I
E
D
A
A
D
Site 59
Y511
E
R
E
I
D
D
T
Y
I
E
D
A
A
D
V
Site 60
S549
Q
K
D
L
P
R
P
S
E
V
N
E
T
I
L
Site 61
T554
R
P
S
E
V
N
E
T
I
L
R
P
L
N
V
Site 62
T566
L
N
V
E
P
P
L
T
D
L
Q
K
S
E
E
Site 63
Y585
E
M
I
T
M
L
H
Y
D
L
L
H
H
P
Y
Site 64
Y592
Y
D
L
L
H
H
P
Y
E
P
S
G
N
K
K
Site 65
T602
S
G
N
K
K
G
K
T
V
G
F
G
T
N
N
Site 66
S610
V
G
F
G
T
N
N
S
E
H
I
T
Y
L
E
Site 67
T614
T
N
N
S
E
H
I
T
Y
L
E
H
N
P
Y
Site 68
Y615
N
N
S
E
H
I
T
Y
L
E
H
N
P
Y
E
Site 69
Y621
T
Y
L
E
H
N
P
Y
E
K
F
S
K
E
E
Site 70
S654
M
S
H
G
E
L
S
S
E
A
Y
N
Q
V
W
Site 71
Y657
G
E
L
S
S
E
A
Y
N
Q
V
W
E
E
C
Site 72
Y670
E
C
Y
S
Q
V
L
Y
L
P
G
Q
S
R
Y
Site 73
Y677
Y
L
P
G
Q
S
R
Y
T
R
A
N
L
A
S
Site 74
T678
L
P
G
Q
S
R
Y
T
R
A
N
L
A
S
K
Site 75
S684
Y
T
R
A
N
L
A
S
K
K
D
R
I
E
S
Site 76
S691
S
K
K
D
R
I
E
S
L
E
K
R
L
E
I
Site 77
T705
I
N
R
G
H
M
T
T
E
A
K
R
A
A
K
Site 78
Y788
E
K
E
L
Q
H
R
Y
A
D
L
L
L
E
K
Site 79
T797
D
L
L
L
E
K
E
T
L
K
S
K
F
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation