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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNN2
Full Name:
Calponin-2
Alias:
Calponin 2; Calponin H2, smooth muscle; CLP2; Neutral calponin
Type:
Intercellular junction, Cytoskeleton protein
Mass (Da):
33697
Number AA:
309
UniProt ID:
Q99439
International Prot ID:
IPI00015262
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005911
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005516
PhosphoSite+
KinaseNET
Biological Process:
GO:0031032
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
Q
F
N
K
G
P
S
Y
G
L
S
A
E
V
K
Site 2
S15
K
G
P
S
Y
G
L
S
A
E
V
K
N
R
L
Site 3
S24
E
V
K
N
R
L
L
S
K
Y
D
P
Q
K
E
Site 4
Y26
K
N
R
L
L
S
K
Y
D
P
Q
K
E
A
E
Site 5
S45
I
E
G
L
T
G
L
S
I
G
P
D
F
Q
K
Site 6
T58
Q
K
G
L
K
D
G
T
I
L
C
T
L
M
N
Site 7
T62
K
D
G
T
I
L
C
T
L
M
N
K
L
Q
P
Site 8
S71
M
N
K
L
Q
P
G
S
V
P
K
I
N
R
S
Site 9
S138
A
K
T
K
G
L
Q
S
G
V
D
I
G
V
K
Site 10
Y146
G
V
D
I
G
V
K
Y
S
E
K
Q
E
R
N
Site 11
S147
V
D
I
G
V
K
Y
S
E
K
Q
E
R
N
F
Site 12
S177
M
G
T
N
K
C
A
S
Q
S
G
M
T
A
Y
Site 13
Y184
S
Q
S
G
M
T
A
Y
G
T
R
R
H
L
Y
Site 14
T186
S
G
M
T
A
y
G
T
R
R
H
L
Y
D
P
Site 15
Y191
Y
G
T
R
R
H
L
Y
D
P
K
N
H
I
L
Site 16
T205
L
P
P
M
D
H
S
T
I
S
L
Q
M
G
T
Site 17
S207
P
M
D
H
S
T
I
S
L
Q
M
G
T
N
K
Site 18
S217
M
G
T
N
K
C
A
S
Q
V
G
M
T
A
P
Site 19
T222
C
A
S
Q
V
G
M
T
A
P
G
T
R
R
H
Site 20
T226
V
G
M
T
A
P
G
T
R
R
H
I
Y
D
T
Site 21
Y231
P
G
T
R
R
H
I
Y
D
T
K
L
G
T
D
Site 22
T233
T
R
R
H
I
Y
D
T
K
L
G
T
D
K
C
Site 23
S243
G
T
D
K
C
D
N
S
S
M
S
L
Q
M
G
Site 24
S244
T
D
K
C
D
N
S
S
M
S
L
Q
M
G
Y
Site 25
S246
K
C
D
N
S
S
M
S
L
Q
M
G
Y
T
Q
Site 26
Y251
S
M
S
L
Q
M
G
Y
T
Q
G
A
N
Q
S
Site 27
T252
M
S
L
Q
M
G
Y
T
Q
G
A
N
Q
S
G
Site 28
S258
Y
T
Q
G
A
N
Q
S
G
Q
V
F
G
L
G
Site 29
Y269
F
G
L
G
R
Q
I
Y
D
P
K
Y
C
P
Q
Site 30
Y273
R
Q
I
Y
D
P
K
Y
C
P
Q
G
T
V
A
Site 31
T278
P
K
Y
C
P
Q
G
T
V
A
D
G
A
P
S
Site 32
Y299
D
P
G
E
V
P
E
Y
P
P
Y
Y
Q
E
E
Site 33
Y302
E
V
P
E
Y
P
P
Y
Y
Q
E
E
A
G
Y
Site 34
Y303
V
P
E
Y
P
P
Y
Y
Q
E
E
A
G
Y
_
Site 35
Y309
Y
Y
Q
E
E
A
G
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation