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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CLCC1
Full Name:
Chloride channel CLIC-like protein 1
Alias:
Chloride channel CLIC-like 1; KIAA0761; MCLC; Mid1-related chloride channel; Mid-1-related chloride channel 1
Type:
Endoplasmic reticulum; Membrane protein, integral; Channel, chloride
Mass (Da):
62023
Number AA:
551
UniProt ID:
Q96S66
International Prot ID:
IPI00045511
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005783
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y32
D
P
T
D
M
L
N
Y
D
A
A
S
G
T
M
Site 2
T38
N
Y
D
A
A
S
G
T
M
R
K
S
Q
A
K
Site 3
S42
A
S
G
T
M
R
K
S
Q
A
K
Y
G
I
S
Site 4
Y46
M
R
K
S
Q
A
K
Y
G
I
S
G
E
K
D
Site 5
S55
I
S
G
E
K
D
V
S
P
D
L
S
C
A
D
Site 6
S59
K
D
V
S
P
D
L
S
C
A
D
E
I
S
E
Site 7
S73
E
C
Y
H
K
L
D
S
L
T
Y
K
I
D
E
Site 8
T75
Y
H
K
L
D
S
L
T
Y
K
I
D
E
C
E
Site 9
Y89
E
K
K
K
R
E
D
Y
E
S
Q
S
N
P
V
Site 10
S91
K
K
R
E
D
Y
E
S
Q
S
N
P
V
F
R
Site 11
S93
R
E
D
Y
E
S
Q
S
N
P
V
F
R
R
Y
Site 12
Y100
S
N
P
V
F
R
R
Y
L
N
K
I
L
I
E
Site 13
Y123
E
N
K
G
D
M
H
Y
D
A
E
I
I
L
K
Site 14
Y206
V
A
T
E
L
W
T
Y
V
R
W
Y
T
Q
L
Site 15
Y210
L
W
T
Y
V
R
W
Y
T
Q
L
R
R
V
L
Site 16
Y282
K
D
D
P
C
Q
K
Y
Y
E
L
L
L
V
N
Site 17
Y351
L
A
I
L
S
F
C
Y
G
A
G
K
S
V
H
Site 18
S368
R
H
I
G
G
P
E
S
E
P
P
Q
A
L
R
Site 19
Y387
R
R
Q
E
E
I
D
Y
R
P
D
G
G
A
G
Site 20
Y400
A
G
D
A
D
F
H
Y
R
G
Q
M
G
P
T
Site 21
Y412
G
P
T
E
Q
G
P
Y
A
K
T
Y
E
G
R
Site 22
T415
E
Q
G
P
Y
A
K
T
Y
E
G
R
R
E
I
Site 23
Y416
Q
G
P
Y
A
K
T
Y
E
G
R
R
E
I
L
Site 24
T434
D
V
D
L
R
F
Q
T
G
N
K
S
P
E
V
Site 25
S438
R
F
Q
T
G
N
K
S
P
E
V
L
R
A
F
Site 26
T457
A
E
A
R
E
H
P
T
V
V
P
S
H
K
S
Site 27
S461
E
H
P
T
V
V
P
S
H
K
S
P
V
L
D
Site 28
S464
T
V
V
P
S
H
K
S
P
V
L
D
T
K
P
Site 29
T469
H
K
S
P
V
L
D
T
K
P
K
E
T
G
G
Site 30
T474
L
D
T
K
P
K
E
T
G
G
I
L
G
E
G
Site 31
T482
G
G
I
L
G
E
G
T
P
K
E
S
S
T
E
Site 32
S486
G
E
G
T
P
K
E
S
S
T
E
S
S
Q
S
Site 33
S487
E
G
T
P
K
E
S
S
T
E
S
S
Q
S
A
Site 34
T488
G
T
P
K
E
S
S
T
E
S
S
Q
S
A
K
Site 35
S490
P
K
E
S
S
T
E
S
S
Q
S
A
K
P
V
Site 36
S491
K
E
S
S
T
E
S
S
Q
S
A
K
P
V
S
Site 37
S493
S
S
T
E
S
S
Q
S
A
K
P
V
S
G
Q
Site 38
S498
S
Q
S
A
K
P
V
S
G
Q
D
T
S
G
N
Site 39
T502
K
P
V
S
G
Q
D
T
S
G
N
T
E
G
S
Site 40
S503
P
V
S
G
Q
D
T
S
G
N
T
E
G
S
P
Site 41
S509
T
S
G
N
T
E
G
S
P
A
A
E
K
A
Q
Site 42
S519
A
E
K
A
Q
L
K
S
E
A
A
G
S
P
D
Site 43
S524
L
K
S
E
A
A
G
S
P
D
Q
G
S
T
Y
Site 44
S529
A
G
S
P
D
Q
G
S
T
Y
S
P
A
R
G
Site 45
T530
G
S
P
D
Q
G
S
T
Y
S
P
A
R
G
V
Site 46
Y531
S
P
D
Q
G
S
T
Y
S
P
A
R
G
V
A
Site 47
S532
P
D
Q
G
S
T
Y
S
P
A
R
G
V
A
G
Site 48
S547
P
R
G
Q
D
P
V
S
S
P
C
G
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation