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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP1R10
Full Name:
Serine/threonine-protein phosphatase 1 regulatory subunit 10
Alias:
Phosphatase 1 nuclear targeting subunit
Type:
Mass (Da):
99040
Number AA:
940
UniProt ID:
Q96QC0
International Prot ID:
IPI00298731
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006605
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
E
L
L
K
G
L
D
S
F
L
N
R
D
G
E
Site 2
S27
N
R
D
G
E
V
K
S
V
D
G
I
S
K
I
Site 3
S32
V
K
S
V
D
G
I
S
K
I
F
S
L
M
K
Site 4
S36
D
G
I
S
K
I
F
S
L
M
K
E
A
R
K
Site 5
T80
K
L
L
N
N
W
L
T
Y
S
K
T
T
N
N
Site 6
T84
N
W
L
T
Y
S
K
T
T
N
N
I
P
L
L
Site 7
T104
T
L
Q
H
L
P
L
T
V
D
H
L
K
Q
N
Site 8
S121
A
K
L
V
K
Q
L
S
K
S
S
E
D
E
E
Site 9
S123
L
V
K
Q
L
S
K
S
S
E
D
E
E
L
R
Site 10
S134
E
E
L
R
K
L
A
S
V
L
V
S
D
W
M
Site 11
S138
K
L
A
S
V
L
V
S
D
W
M
A
V
I
R
Site 12
S146
D
W
M
A
V
I
R
S
Q
S
S
T
Q
P
A
Site 13
S148
M
A
V
I
R
S
Q
S
S
T
Q
P
A
E
K
Site 14
S149
A
V
I
R
S
Q
S
S
T
Q
P
A
E
K
D
Site 15
T150
V
I
R
S
Q
S
S
T
Q
P
A
E
K
D
K
Site 16
T169
D
E
G
K
S
R
T
T
L
P
E
R
P
L
T
Site 17
T176
T
L
P
E
R
P
L
T
E
V
K
A
E
T
R
Site 18
S197
K
K
R
E
K
P
K
S
L
R
T
T
A
P
S
Site 19
T200
E
K
P
K
S
L
R
T
T
A
P
S
H
A
K
Site 20
T201
K
P
K
S
L
R
T
T
A
P
S
H
A
K
F
Site 21
S204
S
L
R
T
T
A
P
S
H
A
K
F
R
S
T
Site 22
T211
S
H
A
K
F
R
S
T
G
L
E
L
E
T
P
Site 23
S219
G
L
E
L
E
T
P
S
L
V
P
V
K
K
N
Site 24
T229
P
V
K
K
N
A
S
T
V
V
V
S
D
K
Y
Site 25
Y236
T
V
V
V
S
D
K
Y
N
L
K
P
I
P
L
Site 26
S247
P
I
P
L
K
R
Q
S
N
V
A
A
P
G
D
Site 27
T256
V
A
A
P
G
D
A
T
P
P
A
E
K
K
Y
Site 28
Y263
T
P
P
A
E
K
K
Y
K
P
L
N
T
T
P
Site 29
T268
K
K
Y
K
P
L
N
T
T
P
N
A
T
K
E
Site 30
T269
K
Y
K
P
L
N
T
T
P
N
A
T
K
E
I
Site 31
S297
G
F
L
D
A
L
N
S
A
P
V
P
G
I
K
Site 32
S313
K
K
K
K
K
V
L
S
P
T
A
A
K
P
S
Site 33
S320
S
P
T
A
A
K
P
S
P
F
E
G
K
T
S
Site 34
S327
S
P
F
E
G
K
T
S
T
E
P
S
T
A
K
Site 35
S331
G
K
T
S
T
E
P
S
T
A
K
P
S
S
P
Site 36
T332
K
T
S
T
E
P
S
T
A
K
P
S
S
P
E
Site 37
S337
P
S
T
A
K
P
S
S
P
E
P
A
P
P
S
Site 38
S344
S
P
E
P
A
P
P
S
E
A
M
D
A
D
R
Site 39
T354
M
D
A
D
R
P
G
T
P
V
P
P
V
E
V
Site 40
T367
E
V
P
E
L
M
D
T
A
S
L
E
P
G
A
Site 41
S369
P
E
L
M
D
T
A
S
L
E
P
G
A
L
D
Site 42
S382
L
D
A
K
P
V
E
S
P
G
D
P
N
Q
L
Site 43
T390
P
G
D
P
N
Q
L
T
R
K
G
R
K
R
K
Site 44
S398
R
K
G
R
K
R
K
S
V
T
W
P
E
E
G
Site 45
Y410
E
E
G
K
L
R
E
Y
F
Y
F
E
L
D
E
Site 46
Y412
G
K
L
R
E
Y
F
Y
F
E
L
D
E
T
E
Site 47
T418
F
Y
F
E
L
D
E
T
E
R
V
N
V
N
K
Site 48
S439
A
A
K
R
E
I
L
S
D
R
H
A
F
E
T
Site 49
T446
S
D
R
H
A
F
E
T
A
R
R
L
S
H
D
Site 50
S451
F
E
T
A
R
R
L
S
H
D
N
M
E
E
K
Site 51
S471
P
R
P
L
V
L
P
S
P
L
V
T
P
G
S
Site 52
T475
V
L
P
S
P
L
V
T
P
G
S
N
S
Q
E
Site 53
S478
S
P
L
V
T
P
G
S
N
S
Q
E
R
Y
I
Site 54
S480
L
V
T
P
G
S
N
S
Q
E
R
Y
I
Q
A
Site 55
Y484
G
S
N
S
Q
E
R
Y
I
Q
A
E
R
E
K
Site 56
S503
E
L
F
L
N
K
E
S
P
H
E
P
D
P
E
Site 57
Y512
H
E
P
D
P
E
P
Y
E
P
I
P
P
K
L
Site 58
S527
I
P
L
D
E
E
C
S
M
D
E
T
P
Y
V
Site 59
T531
E
E
C
S
M
D
E
T
P
Y
V
E
T
L
E
Site 60
Y533
C
S
M
D
E
T
P
Y
V
E
T
L
E
P
G
Site 61
T536
D
E
T
P
Y
V
E
T
L
E
P
G
G
S
G
Site 62
S542
E
T
L
E
P
G
G
S
G
G
S
P
D
G
A
Site 63
S545
E
P
G
G
S
G
G
S
P
D
G
A
G
G
S
Site 64
S552
S
P
D
G
A
G
G
S
K
L
P
P
V
L
A
Site 65
S587
N
V
Q
E
I
L
T
S
I
M
G
S
P
N
S
Site 66
S591
I
L
T
S
I
M
G
S
P
N
S
H
P
S
E
Site 67
S594
S
I
M
G
S
P
N
S
H
P
S
E
E
L
L
Site 68
S597
G
S
P
N
S
H
P
S
E
E
L
L
K
Q
P
Site 69
Y606
E
L
L
K
Q
P
D
Y
S
D
K
I
K
Q
M
Site 70
S607
L
L
K
Q
P
D
Y
S
D
K
I
K
Q
M
L
Site 71
Y703
P
G
P
G
P
G
P
Y
H
R
G
R
G
G
R
Site 72
S730
R
G
A
R
G
G
R
S
G
G
G
P
P
N
G
Site 73
S764
P
G
G
G
M
G
N
S
S
G
H
R
P
H
E
Site 74
S765
G
G
G
M
G
N
S
S
G
H
R
P
H
E
G
Site 75
S779
G
P
G
G
G
M
G
S
G
H
R
P
H
E
G
Site 76
S790
P
H
E
G
P
G
G
S
M
G
G
G
G
G
H
Site 77
S808
E
G
P
G
G
G
I
S
G
G
S
G
H
R
P
Site 78
S811
G
G
G
I
S
G
G
S
G
H
R
P
H
E
G
Site 79
S838
P
H
E
G
P
G
G
S
M
G
G
S
G
G
H
Site 80
S842
P
G
G
S
M
G
G
S
G
G
H
R
P
H
E
Site 81
S901
R
G
H
D
G
G
H
S
H
G
G
D
M
S
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation