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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CaMK1-gamma
Full Name:
Calcium/calmodulin-dependent protein kinase type 1G
Alias:
Calcium/calmodulin-dependent protein kinase I gamma; Calcium/calmodulin-dependent protein kinase IG; CaMK-like CREB kinase III; CLICK III; CLICKIII; DJ272L16.1; EC 2.7.11.17; KCC1G; Kinase CaMK1-gamma; VWS1
Type:
Golgi membrane, Calcium- and calmodulin-dependent protein kinase complex, Cytoplasm, Plasma membrane, Golgi apparatus protein
Mass (Da):
53087
Number AA:
476
UniProt ID:
Q96NX5
International Prot ID:
IPI00000026
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0019898
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005516
GO:0004683
PhosphoSite+
KinaseNET
Biological Process:
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Autocamtide-2 peptide - Autocamtide 2 CaMK2-derived peptide substrate - Powder PE-01ACM95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01ACM95#CREB1 (123-135) KinSub - cyclic-AMP response element binding protein-1 (K123-R135, human) peptide; Crebtide protein kinase substrate peptide - Powder PE-01ACP95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01ACP95
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
R
K
E
E
D
D
C
S
S
W
K
K
Q
T
T
Site 2
S11
K
E
E
D
D
C
S
S
W
K
K
Q
T
T
N
Site 3
T17
S
S
W
K
K
Q
T
T
N
I
R
K
T
F
I
Site 4
S57
A
L
K
C
I
K
K
S
P
A
F
R
D
S
S
Site 5
S63
K
S
P
A
F
R
D
S
S
L
E
N
E
I
A
Site 6
S64
S
P
A
F
R
D
S
S
L
E
N
E
I
A
V
Site 7
T82
I
K
H
E
N
I
V
T
L
E
D
I
Y
E
S
Site 8
Y87
I
V
T
L
E
D
I
Y
E
S
T
T
H
Y
Y
Site 9
Y94
Y
E
S
T
T
H
Y
Y
L
V
M
Q
L
V
S
Site 10
Y115
R
I
L
E
R
G
V
Y
T
E
K
D
A
S
L
Site 11
S121
V
Y
T
E
K
D
A
S
L
V
I
Q
Q
V
L
Site 12
Y151
L
K
P
E
N
L
L
Y
L
T
P
E
E
N
S
Site 13
T153
P
E
N
L
L
Y
L
T
P
E
E
N
S
K
I
Site 14
T163
E
N
S
K
I
M
I
T
D
F
G
L
S
K
M
Site 15
T178
E
Q
N
G
I
M
S
T
A
C
G
T
P
G
Y
Site 16
Y185
T
A
C
G
T
P
G
Y
V
A
P
E
V
L
A
Site 17
S197
V
L
A
Q
K
P
Y
S
K
A
V
D
C
W
S
Site 18
Y220
L
C
G
Y
P
P
F
Y
E
E
T
E
S
K
L
Site 19
S225
P
F
Y
E
E
T
E
S
K
L
F
E
K
I
K
Site 20
Y235
F
E
K
I
K
E
G
Y
Y
E
F
E
S
P
F
Site 21
Y236
E
K
I
K
E
G
Y
Y
E
F
E
S
P
F
W
Site 22
S247
S
P
F
W
D
D
I
S
E
S
A
K
D
F
I
Site 23
Y266
E
K
D
P
N
E
R
Y
T
C
E
K
A
L
S
Site 24
T267
K
D
P
N
E
R
Y
T
C
E
K
A
L
S
H
Site 25
S290
L
H
R
D
I
Y
P
S
V
S
L
Q
I
Q
K
Site 26
S326
K
L
H
M
N
L
H
S
P
G
V
R
P
E
V
Site 27
T340
V
E
N
R
P
P
E
T
Q
A
S
E
T
S
R
Site 28
S343
R
P
P
E
T
Q
A
S
E
T
S
R
P
S
S
Site 29
T345
P
E
T
Q
A
S
E
T
S
R
P
S
S
P
E
Site 30
S346
E
T
Q
A
S
E
T
S
R
P
S
S
P
E
I
Site 31
S349
A
S
E
T
S
R
P
S
S
P
E
I
T
I
T
Site 32
S350
S
E
T
S
R
P
S
S
P
E
I
T
I
T
E
Site 33
T354
R
P
S
S
P
E
I
T
I
T
E
A
P
V
L
Site 34
T356
S
S
P
E
I
T
I
T
E
A
P
V
L
D
H
Site 35
T382
C
Q
H
G
R
R
P
T
A
P
G
G
R
S
L
Site 36
S388
P
T
A
P
G
G
R
S
L
N
C
L
V
N
G
Site 37
S402
G
S
L
H
I
S
S
S
L
V
P
M
H
Q
G
Site 38
S427
S
S
C
L
N
I
G
S
K
G
K
S
S
Y
C
Site 39
S431
N
I
G
S
K
G
K
S
S
Y
C
S
E
P
T
Site 40
S432
I
G
S
K
G
K
S
S
Y
C
S
E
P
T
L
Site 41
S435
K
G
K
S
S
Y
C
S
E
P
T
L
L
K
K
Site 42
S451
N
K
K
Q
N
F
K
S
E
V
M
V
P
V
K
Site 43
S463
P
V
K
A
S
G
S
S
H
C
R
A
G
Q
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation