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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIRREL
Full Name:
Kin of IRRE-like protein 1
Alias:
Kin of IRRE like; Kin of irregular chiasm-like protein 1; KIRR1; NEPH1; Nephrin-like protein 1
Type:
Adhesion protein
Mass (Da):
83536
Number AA:
757
UniProt ID:
Q96J84
International Prot ID:
IPI00470360
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
W
I
L
T
L
S
D
T
F
S
Q
G
T
Q
T
Site 2
S16
L
T
L
S
D
T
F
S
Q
G
T
Q
T
R
F
Site 3
T31
S
Q
E
P
A
D
Q
T
V
V
A
G
Q
R
A
Site 4
Y369
T
Q
A
D
A
G
T
Y
T
C
R
A
I
V
P
Site 5
T370
Q
A
D
A
G
T
Y
T
C
R
A
I
V
P
R
Site 6
Y521
I
A
L
V
F
F
L
Y
R
R
R
K
G
S
R
Site 7
S527
L
Y
R
R
R
K
G
S
R
K
D
V
T
L
R
Site 8
T532
K
G
S
R
K
D
V
T
L
R
K
L
D
I
K
Site 9
T542
K
L
D
I
K
V
E
T
V
N
R
E
P
L
T
Site 10
T549
T
V
N
R
E
P
L
T
M
H
S
D
R
E
D
Site 11
S552
R
E
P
L
T
M
H
S
D
R
E
D
D
T
A
Site 12
T558
H
S
D
R
E
D
D
T
A
S
V
S
T
A
T
Site 13
S560
D
R
E
D
D
T
A
S
V
S
T
A
T
R
V
Site 14
S562
E
D
D
T
A
S
V
S
T
A
T
R
V
M
K
Site 15
Y572
T
R
V
M
K
A
I
Y
S
S
F
K
D
D
V
Site 16
S574
V
M
K
A
I
Y
S
S
F
K
D
D
V
D
L
Site 17
T589
K
Q
D
L
R
C
D
T
I
D
T
R
E
E
Y
Site 18
T592
L
R
C
D
T
I
D
T
R
E
E
Y
E
M
K
Site 19
Y596
T
I
D
T
R
E
E
Y
E
M
K
D
P
T
N
Site 20
T602
E
Y
E
M
K
D
P
T
N
G
Y
Y
N
V
R
Site 21
Y605
M
K
D
P
T
N
G
Y
Y
N
V
R
A
H
E
Site 22
Y606
K
D
P
T
N
G
Y
Y
N
V
R
A
H
E
D
Site 23
S616
R
A
H
E
D
R
P
S
S
R
A
V
L
Y
A
Site 24
S617
A
H
E
D
R
P
S
S
R
A
V
L
Y
A
D
Site 25
Y622
P
S
S
R
A
V
L
Y
A
D
Y
R
A
P
G
Site 26
Y625
R
A
V
L
Y
A
D
Y
R
A
P
G
P
A
R
Site 27
S638
A
R
F
D
G
R
P
S
S
R
L
S
H
S
S
Site 28
S639
R
F
D
G
R
P
S
S
R
L
S
H
S
S
G
Site 29
S642
G
R
P
S
S
R
L
S
H
S
S
G
Y
A
Q
Site 30
S644
P
S
S
R
L
S
H
S
S
G
Y
A
Q
L
N
Site 31
S645
S
S
R
L
S
H
S
S
G
Y
A
Q
L
N
T
Site 32
Y647
R
L
S
H
S
S
G
Y
A
Q
L
N
T
Y
S
Site 33
T652
S
G
Y
A
Q
L
N
T
Y
S
R
G
P
A
S
Site 34
Y653
G
Y
A
Q
L
N
T
Y
S
R
G
P
A
S
D
Site 35
S654
Y
A
Q
L
N
T
Y
S
R
G
P
A
S
D
Y
Site 36
S659
T
Y
S
R
G
P
A
S
D
Y
G
P
E
P
T
Site 37
Y661
S
R
G
P
A
S
D
Y
G
P
E
P
T
P
P
Site 38
T666
S
D
Y
G
P
E
P
T
P
P
G
P
A
A
P
Site 39
T678
A
A
P
A
G
T
D
T
T
S
Q
L
S
Y
E
Site 40
S680
P
A
G
T
D
T
T
S
Q
L
S
Y
E
N
Y
Site 41
S683
T
D
T
T
S
Q
L
S
Y
E
N
Y
E
K
F
Site 42
Y684
D
T
T
S
Q
L
S
Y
E
N
Y
E
K
F
N
Site 43
Y687
S
Q
L
S
Y
E
N
Y
E
K
F
N
S
H
P
Site 44
S692
E
N
Y
E
K
F
N
S
H
P
F
P
G
A
A
Site 45
Y701
P
F
P
G
A
A
G
Y
P
T
Y
R
L
G
Y
Site 46
T703
P
G
A
A
G
Y
P
T
Y
R
L
G
Y
P
Q
Site 47
Y704
G
A
A
G
Y
P
T
Y
R
L
G
Y
P
Q
A
Site 48
Y708
Y
P
T
Y
R
L
G
Y
P
Q
A
P
P
S
G
Site 49
S714
G
Y
P
Q
A
P
P
S
G
L
E
R
T
P
Y
Site 50
T719
P
P
S
G
L
E
R
T
P
Y
E
A
Y
D
P
Site 51
Y721
S
G
L
E
R
T
P
Y
E
A
Y
D
P
I
G
Site 52
Y724
E
R
T
P
Y
E
A
Y
D
P
I
G
K
Y
A
Site 53
Y730
A
Y
D
P
I
G
K
Y
A
T
A
T
R
F
S
Site 54
T732
D
P
I
G
K
Y
A
T
A
T
R
F
S
Y
T
Site 55
T734
I
G
K
Y
A
T
A
T
R
F
S
Y
T
S
Q
Site 56
S737
Y
A
T
A
T
R
F
S
Y
T
S
Q
H
S
D
Site 57
Y738
A
T
A
T
R
F
S
Y
T
S
Q
H
S
D
Y
Site 58
T739
T
A
T
R
F
S
Y
T
S
Q
H
S
D
Y
G
Site 59
S740
A
T
R
F
S
Y
T
S
Q
H
S
D
Y
G
Q
Site 60
S743
F
S
Y
T
S
Q
H
S
D
Y
G
Q
R
F
Q
Site 61
Y745
Y
T
S
Q
H
S
D
Y
G
Q
R
F
Q
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation