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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBRG4
Full Name:
Protein TBRG4
Alias:
Cell cycle progression 2 protein; Cell cycle progression restoration protein 2; CPR2; FAST kinase domain-containing protein 4; FAST kinase domains 4; FASTKD4; H_TD2522F11.8; KIAA0948
Type:
Mass (Da):
70738
Number AA:
631
UniProt ID:
Q969Z0
International Prot ID:
IPI00477123
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005515
GO:0004672
PhosphoSite+
KinaseNET
Biological Process:
GO:0000080
GO:0006915
GO:0007050
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T38
L
A
W
V
A
H
K
T
L
T
S
S
A
T
S
Site 2
S41
V
A
H
K
T
L
T
S
S
A
T
S
P
I
S
Site 3
S42
A
H
K
T
L
T
S
S
A
T
S
P
I
S
H
Site 4
T44
K
T
L
T
S
S
A
T
S
P
I
S
H
L
P
Site 5
S45
T
L
T
S
S
A
T
S
P
I
S
H
L
P
G
Site 6
S48
S
S
A
T
S
P
I
S
H
L
P
G
S
L
M
Site 7
S53
P
I
S
H
L
P
G
S
L
M
E
P
V
E
K
Site 8
S64
P
V
E
K
E
R
A
S
T
P
Y
I
E
K
Q
Site 9
T65
V
E
K
E
R
A
S
T
P
Y
I
E
K
Q
V
Site 10
Y67
K
E
R
A
S
T
P
Y
I
E
K
Q
V
D
H
Site 11
S97
G
G
S
H
D
L
D
S
N
Q
A
A
M
V
L
Site 12
S112
I
R
L
S
H
L
L
S
E
K
P
E
D
K
G
Site 13
S167
K
A
S
K
E
L
Q
S
V
E
Q
E
V
R
W
Site 14
T193
F
L
A
E
S
C
A
T
L
S
Q
E
Q
H
S
Site 15
S195
A
E
S
C
A
T
L
S
Q
E
Q
H
S
Q
E
Site 16
T216
T
H
L
E
R
R
W
T
E
I
E
D
S
H
T
Site 17
T223
T
E
I
E
D
S
H
T
L
V
T
V
M
M
K
Site 18
T226
E
D
S
H
T
L
V
T
V
M
M
K
V
G
H
Site 19
S306
A
Y
A
Y
G
K
L
S
F
H
Q
T
Q
V
S
Site 20
T310
G
K
L
S
F
H
Q
T
Q
V
S
Q
R
L
A
Site 21
S313
S
F
H
Q
T
Q
V
S
Q
R
L
A
T
D
L
Site 22
S391
D
Q
E
D
Q
F
F
S
L
V
H
E
K
L
G
Site 23
S399
L
V
H
E
K
L
G
S
E
L
P
G
L
E
P
Site 24
S444
I
Q
F
L
G
G
K
S
Q
K
D
Q
N
T
F
Site 25
T450
K
S
Q
K
D
Q
N
T
F
Q
K
L
L
H
I
Site 26
Y465
N
A
T
A
L
L
E
Y
P
E
Y
S
G
P
L
Site 27
S469
L
L
E
Y
P
E
Y
S
G
P
L
L
P
A
S
Site 28
T490
S
A
L
D
R
K
V
T
P
L
Q
K
E
L
Q
Site 29
T499
L
Q
K
E
L
Q
E
T
L
K
G
L
L
G
S
Site 30
S506
T
L
K
G
L
L
G
S
A
D
K
G
S
L
E
Site 31
S511
L
G
S
A
D
K
G
S
L
E
V
A
T
Q
Y
Site 32
T549
A
P
H
L
A
Q
P
T
G
S
Q
S
P
P
P
Site 33
S551
H
L
A
Q
P
T
G
S
Q
S
P
P
P
G
S
Site 34
S553
A
Q
P
T
G
S
Q
S
P
P
P
G
S
K
R
Site 35
S558
S
Q
S
P
P
P
G
S
K
R
L
A
F
L
R
Site 36
Y616
S
E
W
Q
K
G
A
Y
L
K
D
K
M
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation