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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SMARCE1
Full Name:
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
Alias:
BAF57; BRG1-associated factor 57; Mammalian chromatin remodeling complex BRG1-associated factor 57; SMCE1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1
Type:
Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Mass (Da):
46649
Number AA:
411
UniProt ID:
Q969G3
International Prot ID:
IPI00017669
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000228
GO:0005634
GO:0005694
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003682
PhosphoSite+
KinaseNET
Biological Process:
GO:0006325
GO:0006333
GO:0006337
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
K
R
P
S
Y
A
P
P
P
T
P
Site 2
Y7
_
M
S
K
R
P
S
Y
A
P
P
P
T
P
A
Site 3
T12
P
S
Y
A
P
P
P
T
P
A
P
A
T
Q
M
Site 4
T17
P
P
T
P
A
P
A
T
Q
M
P
S
T
P
G
Site 5
S21
A
P
A
T
Q
M
P
S
T
P
G
F
V
G
Y
Site 6
T22
P
A
T
Q
M
P
S
T
P
G
F
V
G
Y
N
Site 7
Y28
S
T
P
G
F
V
G
Y
N
P
Y
S
H
L
A
Site 8
Y31
G
F
V
G
Y
N
P
Y
S
H
L
A
Y
N
N
Site 9
Y36
N
P
Y
S
H
L
A
Y
N
N
Y
R
L
G
G
Site 10
Y39
S
H
L
A
Y
N
N
Y
R
L
G
G
N
P
G
Site 11
T47
R
L
G
G
N
P
G
T
N
S
R
V
T
A
S
Site 12
S49
G
G
N
P
G
T
N
S
R
V
T
A
S
S
G
Site 13
T52
P
G
T
N
S
R
V
T
A
S
S
G
I
T
I
Site 14
S55
N
S
R
V
T
A
S
S
G
I
T
I
P
K
P
Site 15
T58
V
T
A
S
S
G
I
T
I
P
K
P
P
K
P
Site 16
Y73
P
D
K
P
L
M
P
Y
M
R
Y
S
R
K
V
Site 17
Y76
P
L
M
P
Y
M
R
Y
S
R
K
V
W
D
Q
Site 18
T108
G
G
M
W
R
D
L
T
D
E
E
K
Q
E
Y
Site 19
Y115
T
D
E
E
K
Q
E
Y
L
N
E
Y
E
A
E
Site 20
Y119
K
Q
E
Y
L
N
E
Y
E
A
E
K
I
E
Y
Site 21
Y126
Y
E
A
E
K
I
E
Y
N
E
S
M
K
A
Y
Site 22
Y133
Y
N
E
S
M
K
A
Y
H
N
S
P
A
Y
L
Site 23
S136
S
M
K
A
Y
H
N
S
P
A
Y
L
A
Y
I
Site 24
Y139
A
Y
H
N
S
P
A
Y
L
A
Y
I
N
A
K
Site 25
Y142
N
S
P
A
Y
L
A
Y
I
N
A
K
S
R
A
Site 26
S157
E
A
A
L
E
E
E
S
R
Q
R
Q
S
R
M
Site 27
S162
E
E
S
R
Q
R
Q
S
R
M
E
K
G
E
P
Site 28
Y170
R
M
E
K
G
E
P
Y
M
S
I
Q
P
A
E
Site 29
S172
E
K
G
E
P
Y
M
S
I
Q
P
A
E
D
P
Site 30
Y182
P
A
E
D
P
D
D
Y
D
D
G
F
S
M
K
Site 31
T191
D
G
F
S
M
K
H
T
A
T
A
R
F
Q
R
Site 32
S204
Q
R
N
H
R
L
I
S
E
I
L
S
E
S
V
Site 33
S233
V
L
K
R
Q
V
Q
S
L
M
V
H
Q
R
K
Site 34
S262
K
K
R
K
F
L
E
S
T
D
S
F
N
N
E
Site 35
T263
K
R
K
F
L
E
S
T
D
S
F
N
N
E
L
Site 36
S265
K
F
L
E
S
T
D
S
F
N
N
E
L
K
R
Site 37
S314
A
A
E
Q
A
E
R
S
Q
S
S
I
V
P
E
Site 38
S316
E
Q
A
E
R
S
Q
S
S
I
V
P
E
E
E
Site 39
S317
Q
A
E
R
S
Q
S
S
I
V
P
E
E
E
Q
Site 40
T345
I
P
M
E
T
E
E
T
H
L
E
E
T
T
E
Site 41
T350
E
E
T
H
L
E
E
T
T
E
S
Q
Q
N
G
Site 42
S353
H
L
E
E
T
T
E
S
Q
Q
N
G
E
E
G
Site 43
S362
Q
N
G
E
E
G
T
S
T
P
E
D
K
E
S
Site 44
T363
N
G
E
E
G
T
S
T
P
E
D
K
E
S
G
Site 45
S369
S
T
P
E
D
K
E
S
G
Q
E
G
V
D
S
Site 46
S376
S
G
Q
E
G
V
D
S
M
A
E
E
G
T
S
Site 47
S383
S
M
A
E
E
G
T
S
D
S
N
T
G
S
E
Site 48
S385
A
E
E
G
T
S
D
S
N
T
G
S
E
S
N
Site 49
T387
E
G
T
S
D
S
N
T
G
S
E
S
N
S
A
Site 50
S389
T
S
D
S
N
T
G
S
E
S
N
S
A
T
V
Site 51
S393
N
T
G
S
E
S
N
S
A
T
V
E
E
P
P
Site 52
T395
G
S
E
S
N
S
A
T
V
E
E
P
P
T
D
Site 53
T401
A
T
V
E
E
P
P
T
D
P
I
P
E
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation