PhosphoNET

           
Protein Info 
   
Short Name:  BRF1
Full Name:  Transcription factor IIIB 90 kDa subunit
Alias:  B-related factor 1; BRF; BRF-1; BRF1, subunit of RNA polymerase III transcription initiation factor IIIB; General transcription factor IIIB, 90kD; GTF3B; TAF3B2; TAF3C; TAFIII90; TATA box binding protein (TBP)-associated factor 3C; TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2; TATA box binding protein (TBP)-associated factor, RNA polymerase III, subunit 2; TATA box-binding protein-associated factor, RNA polymerase III, subunit 2; TBP-associated factor, RNA polymerase III, 90kD; TF3B; TF3B90; TFIIIB90; Transcription factor IIIB 90 kDa; Transcription initiation factor IIIB
Type:  Transcription initiation complex
Mass (Da):  73840
Number AA:  677
UniProt ID:  Q92994
International Prot ID:  IPI00016859
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0000126     Uniprot OncoNet
Molecular Function:  GO:0003709  GO:0005515  GO:0016563 PhosphoSite+ KinaseNET
Biological Process:  GO:0045941  GO:0009303  GO:0006355 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S46SEVQFVESSGGGSSA
Site 2S47EVQFVESSGGGSSAV
Site 3S52ESSGGGSSAVGQFVS
Site 4S59SAVGQFVSLDGAGKT
Site 5T66SLDGAGKTPTLGGGF
Site 6T68DGAGKTPTLGGGFHV
Site 7T85GKESRAQTLQNGRRH
Site 8T123MAVSRHLTRGRKMAH
Site 9T206KNHEVSMTALRLLQR
Site 10T221MKRDWMHTGRRPSGL
Site 11S226MHTGRRPSGLCGAAL
Site 12T245RMHDFRRTVKEVISV
Site 13S258SVVKVCESTLRKRLT
Site 14T259VVKVCESTLRKRLTE
Site 15T265STLRKRLTEFEDTPT
Site 16T270RLTEFEDTPTSQLTI
Site 17T272TEFEDTPTSQLTIDE
Site 18S273EFEDTPTSQLTIDEF
Site 19S293EEECDPPSYTAGQRK
Site 20Y294EECDPPSYTAGQRKL
Site 21S311KQLEQVLSKKLEEVE
Site 22S322EEVEGEISSYQDAIE
Site 23Y324VEGEISSYQDAIEIE
Site 24S335IEIELENSRPKAKGG
Site 25S345KAKGGLASLAKDGST
Site 26S351ASLAKDGSTEDTASS
Site 27T352SLAKDGSTEDTASSL
Site 28T355KDGSTEDTASSLCGE
Site 29S357GSTEDTASSLCGEED
Site 30S358STEDTASSLCGEEDT
Site 31T365SLCGEEDTEDEELEA
Site 32S375EELEAAASHLNKDLY
Site 33Y382SHLNKDLYRELLGGA
Site 34S392LLGGAPGSSEAAGSP
Site 35S393LGGAPGSSEAAGSPE
Site 36S398GSSEAAGSPEWGGRP
Site 37S410GRPPALGSLLDPLPT
Site 38S432DSIRECISSQSSDPK
Site 39S433SIRECISSQSSDPKD
Site 40S436ECISSQSSDPKDASG
Site 41S442SSDPKDASGDGELDL
Site 42S450GDGELDLSGIDDLEI
Site 43Y460DDLEIDRYILNESEA
Site 44Y481WMRENAEYLREQREK
Site 45Y501KEKELGIYKEHKPKK
Site 46S509KEHKPKKSCKRREPI
Site 47S519RREPIQASTAREAIE
Site 48Y540KISSKINYSVLRGLS
Site 49S541ISSKINYSVLRGLSS
Site 50S547YSVLRGLSSAGGGSP
Site 51S548SVLRGLSSAGGGSPH
Site 52S553LSSAGGGSPHREDAQ
Site 53S566AQPEHSASARKLSRR
Site 54S571SASARKLSRRRTPAS
Site 55T575RKLSRRRTPASRSGA
Site 56S578SRRRTPASRSGADPV
Site 57S580RRTPASRSGADPVTS
Site 58T586RSGADPVTSVGKRLR
Site 59S587SGADPVTSVGKRLRP
Site 60S597KRLRPLVSTQPAKKV
Site 61T598RLRPLVSTQPAKKVA
Site 62S613TGEALLPSSPTLGAE
Site 63S614GEALLPSSPTLGAEP
Site 64T616ALLPSSPTLGAEPAR
Site 65S635LVESGPVSYHADEEA
Site 66S657EDGEPCVSALQMMGS
Site 67S664SALQMMGSNDYGCDG
Site 68Y667QMMGSNDYGCDGDED
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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