PhosphoNET

           
Protein Info 
   
Short Name:  IRF-7
Full Name:  Interferon regulatory factor 7
Alias:  IRF7
Type:  Transcription protein, DNA binding protein
Mass (Da):  54278
Number AA:  503
UniProt ID:  Q92985
International Prot ID:  IPI00298041
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0003704  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0044419  GO:0000122  GO:0009615 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y27GEISSGCYEGLQWLD
Site 2S53HFARKDLSEADARIF
Site 3S73ARGRWPPSSRGGGPP
Site 4S74RGRWPPSSRGGGPPP
Site 5T102FRCALRSTRRFVMLR
Site 6S112FVMLRDNSGDPADPH
Site 7Y122PADPHKVYALSRELC
Site 8T136CWREGPGTDQTEAEA
Site 9T139EGPGTDQTEAEAPAA
Site 10T162PGPFLAHTHAGLQAP
Site 11S200ADHLLTASWGADPVP
Site 12T208WGADPVPTKAPGEGQ
Site 13T243YGWAVETTPSPGPQP
Site 14S245WAVETTPSPGPQPAA
Site 15S263GEAAAPESPHQAEPY
Site 16Y270SPHQAEPYLSPSPSA
Site 17S272HQAEPYLSPSPSACT
Site 18S276PYLSPSPSACTAVQE
Site 19T292SPGALDVTIMYKGRT
Site 20S309QKVVGHPSCTFLYGP
Site 21Y314HPSCTFLYGPPDPAV
Site 22T324PDPAVRATDPQQVAF
Site 23S333PQQVAFPSPAELPDQ
Site 24T346DQKQLRYTEELLRHV
Site 25Y377RMGKCKVYWEVGGPP
Site 26S386EVGGPPGSASPSTPA
Site 27S388GGPPGSASPSTPACL
Site 28S390PPGSASPSTPACLLP
Site 29T391PGSASPSTPACLLPR
Site 30S425RARQRRGSPRYTIYL
Site 31Y428QRRGSPRYTIYLGFG
Site 32T429RRGSPRYTIYLGFGQ
Site 33Y431GSPRYTIYLGFGQDL
Site 34S439LGFGQDLSAGRPKEK
Site 35S447AGRPKEKSLVLVKLE
Site 36T465CRVHLEGTQREGVSS
Site 37S471GTQREGVSSLDSSSL
Site 38S472TQREGVSSLDSSSLS
Site 39S475EGVSSLDSSSLSLCL
Site 40S477VSSLDSSSLSLCLSS
Site 41S479SLDSSSLSLCLSSAN
Site 42S483SSLSLCLSSANSLYD
Site 43S484SLSLCLSSANSLYDD
Site 44S487LCLSSANSLYDDIEC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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