PhosphoNET

           
Protein Info 
   
Short Name:  BAD
Full Name:  Bcl2 antagonist of cell death
Alias:  BBC2; BBC6; Bcl- XL/Bcl-2 associated death promoter; Bcl-2 binding component 6; Bcl2-antagonist of cell death; BCL2-associated agonist of cell death; BCL2L8; Bcl-2-like 8 protein; Bcl-xL/Bcl-2 associated death promoter
Type:  Apoptosis protein, Bcl family
Mass (Da):  18392
Number AA:  168
UniProt ID:  Q92934
International Prot ID:  IPI00024291
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005741   Uniprot OncoNet
Molecular Function:  GO:0019901     PhosphoSite+ KinaseNET
Biological Process:  GO:0008633  GO:0008624   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S10QIPEFEPSEQEDSSS
Site 2S15EPSEQEDSSSAERGL
Site 3S16PSEQEDSSSAERGLG
Site 4S17SEQEDSSSAERGLGP
Site 5S25AERGLGPSPAGDGPS
Site 6S32SPAGDGPSGSGKHHR
Site 7S34AGDGPSGSGKHHRQA
Site 8S49PGLLWDASHQQEQPT
Site 9S57HQQEQPTSSSHHGGA
Site 10S58QQEQPTSSSHHGGAG
Site 11S59QEQPTSSSHHGGAGA
Site 12S71AGAVEIRSRHSSYPA
Site 13S74VEIRSRHSSYPAGTE
Site 14S75 EIRSRHSSYPAGTED
Site 15Y76IRSRHSSYPAGTEDD
Site 16T80HSSYPAGTEDDEGMG
Site 17S91EGMGEEPSPFRGRSR
Site 18S97PSPFRGRSRSAPPNL
Site 19S99 PFRGRSRSAPPNLWA
Site 20Y110NLWAAQRYGRELRRM
Site 21S118 GRELRRMSDEFVDSF
Site 22S124MSDEFVDSFKKGLPR
Site 23S134 KGLPRPKSAGTATQM
Site 24T137PRPKSAGTATQMRQS
Site 25T139PKSAGTATQMRQSSS
Site 26S144TATQMRQSSSWTRVF
Site 27S145ATQMRQSSSWTRVFQ
Site 28S146TQMRQSSSWTRVFQS
Site 29S163DRNLGRGSSAPSQ__
Site 30S164RNLGRGSSAPSQ___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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