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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPKOW
Full Name:
G patch domain and KOW motifs-containing protein
Alias:
G patch domain and KOW motifs; G patch domain containing 5; G patch domain-containing protein 5; GPATC5; GPATCH5; T54
Type:
Unknown function
Mass (Da):
52229
Number AA:
476
UniProt ID:
Q92917
International Prot ID:
IPI00024255
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003676
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
K
E
G
V
L
P
L
T
A
A
S
T
A
P
I
Site 2
T24
A
P
I
S
F
G
F
T
R
T
S
A
R
R
R
Site 3
T26
I
S
F
G
F
T
R
T
S
A
R
R
R
L
A
Site 4
S27
S
F
G
F
T
R
T
S
A
R
R
R
L
A
D
Site 5
S35
A
R
R
R
L
A
D
S
G
D
G
A
G
P
S
Site 6
S42
S
G
D
G
A
G
P
S
P
E
E
K
D
F
L
Site 7
T51
E
E
K
D
F
L
K
T
V
E
G
R
E
L
Q
Site 8
S59
V
E
G
R
E
L
Q
S
V
K
P
Q
E
A
P
Site 9
S90
P
A
R
P
P
G
P
S
T
D
T
G
A
L
A
Site 10
T91
A
R
P
P
G
P
S
T
D
T
G
A
L
A
D
Site 11
S102
A
L
A
D
G
V
V
S
Q
A
V
K
E
L
I
Site 12
S115
L
I
A
E
S
K
K
S
L
E
E
R
E
N
A
Site 13
T138
P
M
I
Q
K
G
C
T
P
S
G
E
G
A
D
Site 14
S146
P
S
G
E
G
A
D
S
E
P
R
A
E
T
V
Site 15
T152
D
S
E
P
R
A
E
T
V
P
E
E
A
N
Y
Site 16
Y159
T
V
P
E
E
A
N
Y
E
A
V
P
V
E
A
Site 17
T186
P
G
E
G
I
G
R
T
F
N
Q
V
V
K
P
Site 18
S197
V
V
K
P
R
V
N
S
L
R
P
K
G
L
G
Site 19
T216
L
T
E
A
Q
A
L
T
P
T
G
P
S
R
M
Site 20
S221
A
L
T
P
T
G
P
S
R
M
P
R
P
D
E
Site 21
S251
G
G
A
V
V
V
L
S
G
P
H
R
G
L
Y
Site 22
Y258
S
G
P
H
R
G
L
Y
G
K
V
E
G
L
D
Site 23
S285
G
S
R
V
V
T
V
S
E
Y
Y
L
R
P
V
Site 24
Y287
R
V
V
T
V
S
E
Y
Y
L
R
P
V
S
Q
Site 25
Y288
V
V
T
V
S
E
Y
Y
L
R
P
V
S
Q
Q
Site 26
S293
E
Y
Y
L
R
P
V
S
Q
Q
E
F
D
K
N
Site 27
T301
Q
Q
E
F
D
K
N
T
L
D
L
R
Q
Q
N
Site 28
T310
D
L
R
Q
Q
N
G
T
A
S
S
R
K
T
L
Site 29
S312
R
Q
Q
N
G
T
A
S
S
R
K
T
L
W
N
Site 30
T316
G
T
A
S
S
R
K
T
L
W
N
Q
E
L
Y
Site 31
Y323
T
L
W
N
Q
E
L
Y
I
Q
Q
D
N
S
E
Site 32
S329
L
Y
I
Q
Q
D
N
S
E
R
K
R
K
H
L
Site 33
S347
Q
D
G
P
A
A
K
S
E
K
A
A
P
R
S
Site 34
S354
S
E
K
A
A
P
R
S
Q
H
W
L
H
R
D
Site 35
Y371
V
R
F
V
D
N
M
Y
K
G
G
Q
Y
Y
N
Site 36
S388
M
I
I
E
D
V
L
S
P
D
T
C
V
C
R
Site 37
T391
E
D
V
L
S
P
D
T
C
V
C
R
T
D
E
Site 38
T412
L
R
E
D
M
L
E
T
L
V
P
K
A
E
G
Site 39
S438
G
R
V
G
H
L
L
S
R
D
R
A
R
S
R
Site 40
S444
L
S
R
D
R
A
R
S
R
A
L
V
Q
L
P
Site 41
Y461
N
Q
V
V
E
L
H
Y
D
A
I
C
Q
Y
M
Site 42
Y467
H
Y
D
A
I
C
Q
Y
M
G
P
S
D
T
D
Site 43
S471
I
C
Q
Y
M
G
P
S
D
T
D
D
D
_
_
Site 44
T473
Q
Y
M
G
P
S
D
T
D
D
D
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation