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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NDRG1
Full Name:
Protein NDRG1
Alias:
CAP43; Differentiation-related gene 1 protein; DRG1; NDR1; Nickel-specific induction protein Cap43; N-myc downstream regulated 1; N-myc downstream regulated gene 1 protein; Reducing agents and tunicamycin-responsive protein; Rit42; RTP; TDD5
Type:
Cell development/differentiation; Vesicle protein
Mass (Da):
42835
Number AA:
394
UniProt ID:
Q92597
International Prot ID:
IPI00022078
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0010038
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
R
E
M
Q
D
V
D
Site 2
T22
P
L
V
E
K
G
E
T
I
T
G
L
L
Q
E
Site 3
T39
V
Q
E
Q
D
I
E
T
L
H
G
S
V
H
V
Site 4
T51
V
H
V
T
L
C
G
T
P
K
G
N
R
P
V
Site 5
Y62
N
R
P
V
I
L
T
Y
H
D
I
G
M
N
H
Site 6
Y79
C
Y
N
P
L
F
N
Y
E
D
M
Q
E
I
T
Site 7
S105
G
Q
Q
D
G
A
A
S
F
P
A
G
Y
M
Y
Site 8
Y110
A
A
S
F
P
A
G
Y
M
Y
P
S
M
D
Q
Site 9
Y112
S
F
P
A
G
Y
M
Y
P
S
M
D
Q
L
A
Site 10
S203
F
G
K
E
E
M
Q
S
N
V
E
V
V
H
T
Site 11
T210
S
N
V
E
V
V
H
T
Y
R
Q
H
I
V
N
Site 12
Y231
L
H
L
F
I
N
A
Y
N
S
R
R
D
L
E
Site 13
S233
L
F
I
N
A
Y
N
S
R
R
D
L
E
I
E
Site 14
T246
I
E
R
P
M
P
G
T
H
T
V
T
L
Q
C
Site 15
T248
R
P
M
P
G
T
H
T
V
T
L
Q
C
P
A
Site 16
T281
S
K
L
D
P
T
K
T
T
L
L
K
M
A
D
Site 17
S296
C
G
G
L
P
Q
I
S
Q
P
A
K
L
A
E
Site 18
Y307
K
L
A
E
A
F
K
Y
F
V
Q
G
M
G
Y
Site 19
S317
Q
G
M
G
Y
M
P
S
A
S
M
T
R
L
M
Site 20
S319
M
G
Y
M
P
S
A
S
M
T
R
L
M
R
S
Site 21
T321
Y
M
P
S
A
S
M
T
R
L
M
R
S
R
T
Site 22
S326
S
M
T
R
L
M
R
S
R
T
A
S
G
S
S
Site 23
T328
T
R
L
M
R
S
R
T
A
S
G
S
S
V
T
Site 24
S330
L
M
R
S
R
T
A
S
G
S
S
V
T
S
L
Site 25
S332
R
S
R
T
A
S
G
S
S
V
T
S
L
D
G
Site 26
S333
S
R
T
A
S
G
S
S
V
T
S
L
D
G
T
Site 27
T335
T
A
S
G
S
S
V
T
S
L
D
G
T
R
S
Site 28
S336
A
S
G
S
S
V
T
S
L
D
G
T
R
S
R
Site 29
T340
S
V
T
S
L
D
G
T
R
S
R
S
H
T
S
Site 30
S342
T
S
L
D
G
T
R
S
R
S
H
T
S
E
G
Site 31
S344
L
D
G
T
R
S
R
S
H
T
S
E
G
T
R
Site 32
T346
G
T
R
S
R
S
H
T
S
E
G
T
R
S
R
Site 33
S347
T
R
S
R
S
H
T
S
E
G
T
R
S
R
S
Site 34
T350
R
S
H
T
S
E
G
T
R
S
R
S
H
T
S
Site 35
S352
H
T
S
E
G
T
R
S
R
S
H
T
S
E
G
Site 36
S354
S
E
G
T
R
S
R
S
H
T
S
E
G
T
R
Site 37
S364
S
E
G
T
R
S
R
S
H
T
S
E
G
A
H
Site 38
T366
G
T
R
S
R
S
H
T
S
E
G
A
H
L
D
Site 39
S367
T
R
S
R
S
H
T
S
E
G
A
H
L
D
I
Site 40
T375
E
G
A
H
L
D
I
T
P
N
S
G
A
A
G
Site 41
S378
H
L
D
I
T
P
N
S
G
A
A
G
N
S
A
Site 42
S384
N
S
G
A
A
G
N
S
A
G
P
K
S
M
E
Site 43
S389
G
N
S
A
G
P
K
S
M
E
V
S
C
_
_
Site 44
S393
G
P
K
S
M
E
V
S
C
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation