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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ELMO1
Full Name:
Engulfment and cell motility protein 1
Alias:
CED12; CED-12; CED-12 homolog; ELM1; ELMO-1; Engulfment and cell motility 1; KIAA0281
Type:
Cytoskeletal protein
Mass (Da):
83829
Number AA:
727
UniProt ID:
Q92556
International Prot ID:
IPI00219532
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005856
GO:0005829
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0017124
PhosphoSite+
KinaseNET
Biological Process:
GO:0016601
GO:0030036
GO:0006915
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
A
I
E
W
P
G
A
Y
P
K
L
M
E
I
D
Site 2
S31
I
D
Q
K
K
P
L
S
A
I
I
K
E
V
C
Site 3
Y48
W
S
L
A
N
H
E
Y
F
A
L
Q
H
A
D
Site 4
S56
F
A
L
Q
H
A
D
S
S
N
F
Y
I
T
E
Site 5
S57
A
L
Q
H
A
D
S
S
N
F
Y
I
T
E
K
Site 6
Y60
H
A
D
S
S
N
F
Y
I
T
E
K
N
R
N
Site 7
T78
N
G
T
I
L
R
L
T
T
S
P
A
Q
N
A
Site 8
T79
G
T
I
L
R
L
T
T
S
P
A
Q
N
A
Q
Site 9
S80
T
I
L
R
L
T
T
S
P
A
Q
N
A
Q
Q
Site 10
S94
Q
L
H
E
R
I
Q
S
S
S
M
D
A
K
L
Site 11
S96
H
E
R
I
Q
S
S
S
M
D
A
K
L
E
A
Site 12
S109
E
A
L
K
D
L
A
S
L
S
R
D
V
T
F
Site 13
S111
L
K
D
L
A
S
L
S
R
D
V
T
F
A
Q
Site 14
T115
A
S
L
S
R
D
V
T
F
A
Q
E
F
I
N
Site 15
Y140
V
E
S
G
T
E
R
Y
Q
K
L
Q
K
I
M
Site 16
Y216
V
L
N
S
H
D
L
Y
Q
K
V
A
Q
E
I
Site 17
S235
L
I
P
H
L
Q
G
S
D
Q
E
I
Q
T
Y
Site 18
Y242
S
D
Q
E
I
Q
T
Y
T
I
A
V
I
N
A
Site 19
T311
L
L
E
D
R
M
M
T
K
M
D
P
Q
D
Q
Site 20
S336
R
I
A
F
D
A
E
S
E
P
N
N
S
S
G
Site 21
S341
A
E
S
E
P
N
N
S
S
G
S
M
E
K
R
Site 22
S342
E
S
E
P
N
N
S
S
G
S
M
E
K
R
K
Site 23
S344
E
P
N
N
S
S
G
S
M
E
K
R
K
S
M
Site 24
S350
G
S
M
E
K
R
K
S
M
Y
T
R
D
Y
K
Site 25
Y352
M
E
K
R
K
S
M
Y
T
R
D
Y
K
K
L
Site 26
T353
E
K
R
K
S
M
Y
T
R
D
Y
K
K
L
G
Site 27
Y356
K
S
M
Y
T
R
D
Y
K
K
L
G
F
I
N
Site 28
T372
V
N
P
A
M
D
F
T
Q
T
P
P
G
M
L
Site 29
Y386
L
A
L
D
N
M
L
Y
F
A
K
H
H
Q
D
Site 30
Y395
A
K
H
H
Q
D
A
Y
I
R
I
V
L
E
N
Site 31
S403
I
R
I
V
L
E
N
S
S
R
E
D
K
H
E
Site 32
S417
E
C
P
F
G
R
S
S
I
E
L
T
K
M
L
Site 33
S435
L
K
V
G
E
L
P
S
E
T
C
N
D
F
H
Site 34
T447
D
F
H
P
M
F
F
T
H
D
R
S
F
E
E
Site 35
T473
T
W
K
E
M
R
A
T
S
E
D
F
N
K
V
Site 36
T493
E
Q
V
M
R
A
L
T
T
K
P
S
S
L
D
Site 37
T494
Q
V
M
R
A
L
T
T
K
P
S
S
L
D
Q
Site 38
S497
R
A
L
T
T
K
P
S
S
L
D
Q
F
K
S
Site 39
S498
A
L
T
T
K
P
S
S
L
D
Q
F
K
S
K
Site 40
S504
S
S
L
D
Q
F
K
S
K
L
Q
N
L
S
Y
Site 41
Y511
S
K
L
Q
N
L
S
Y
T
E
I
L
K
I
R
Site 42
S520
E
I
L
K
I
R
Q
S
E
R
M
N
Q
E
D
Site 43
S530
M
N
Q
E
D
F
Q
S
R
P
I
L
E
L
K
Site 44
T560
L
N
R
L
V
E
G
T
C
F
R
K
L
N
A
Site 45
Y576
R
R
Q
D
K
F
W
Y
C
R
L
S
P
N
H
Site 46
S594
H
Y
G
D
L
E
E
S
P
Q
G
E
V
P
H
Site 47
S603
Q
G
E
V
P
H
D
S
L
Q
D
K
L
P
V
Site 48
T618
A
D
I
K
A
V
V
T
G
K
D
C
P
H
M
Site 49
Y662
I
A
P
D
K
H
E
Y
C
I
W
T
D
G
L
Site 50
S679
L
L
G
K
D
M
M
S
D
L
T
R
N
D
L
Site 51
T682
K
D
M
M
S
D
L
T
R
N
D
L
D
T
L
Site 52
T688
L
T
R
N
D
L
D
T
L
L
S
M
E
I
K
Site 53
S718
P
P
I
P
K
E
P
S
N
Y
D
F
V
Y
D
Site 54
Y720
I
P
K
E
P
S
N
Y
D
F
V
Y
D
C
N
Site 55
Y724
P
S
N
Y
D
F
V
Y
D
C
N
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation