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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATRIP
Full Name:
ATR-interacting protein
Alias:
ATM and Rad3-related-interacting protein; ATR-interacting protein: ATM and Rad3-related-interacting protein: ATR-interacting protein: ATM and Rad3-related-interacting protein: ATR-interacting protein: ATM and Rad3-related-interacting protein: ATR-interacting protein: ATM and Rad3-related-interacting protein
Type:
Cell cycle regulation; DNA binding protein; DNA repair
Mass (Da):
85838
Number AA:
791
UniProt ID:
Q8WXE1
International Prot ID:
IPI00103517
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0000077
GO:0006281
GO:0006260
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
G
T
S
A
P
G
S
K
R
R
Site 2
S9
A
G
T
S
A
P
G
S
K
R
R
S
E
P
P
Site 3
S13
A
P
G
S
K
R
R
S
E
P
P
A
P
R
P
Site 4
T26
R
P
G
P
P
P
G
T
G
H
P
P
S
K
R
Site 5
S31
P
G
T
G
H
P
P
S
K
R
A
R
G
F
S
Site 6
S38
S
K
R
A
R
G
F
S
A
A
A
A
P
D
P
Site 7
T56
F
G
A
H
G
D
F
T
A
D
D
L
E
E
L
Site 8
T65
D
D
L
E
E
L
D
T
L
A
S
Q
A
L
S
Site 9
S68
E
E
L
D
T
L
A
S
Q
A
L
S
Q
C
P
Site 10
S72
T
L
A
S
Q
A
L
S
Q
C
P
A
A
A
R
Site 11
S82
P
A
A
A
R
D
V
S
S
D
H
K
V
H
R
Site 12
S83
A
A
A
R
D
V
S
S
D
H
K
V
H
R
L
Site 13
S95
H
R
L
L
D
G
M
S
K
N
P
S
G
K
N
Site 14
S99
D
G
M
S
K
N
P
S
G
K
N
R
E
T
V
Site 15
T105
P
S
G
K
N
R
E
T
V
P
I
K
D
N
F
Site 16
S148
E
I
K
I
L
R
D
S
L
H
Q
T
E
S
V
Site 17
T152
L
R
D
S
L
H
Q
T
E
S
V
L
E
E
Q
Site 18
S154
D
S
L
H
Q
T
E
S
V
L
E
E
Q
R
R
Site 19
S162
V
L
E
E
Q
R
R
S
H
F
L
L
E
Q
E
Site 20
T171
F
L
L
E
Q
E
K
T
Q
A
L
S
D
K
E
Site 21
S175
Q
E
K
T
Q
A
L
S
D
K
E
K
E
F
S
Site 22
S182
S
D
K
E
K
E
F
S
K
K
L
Q
S
L
Q
Site 23
S187
E
F
S
K
K
L
Q
S
L
Q
S
E
L
Q
F
Site 24
S190
K
K
L
Q
S
L
Q
S
E
L
Q
F
K
D
A
Site 25
T208
E
L
R
T
K
L
Q
T
S
E
R
A
N
K
L
Site 26
S209
L
R
T
K
L
Q
T
S
E
R
A
N
K
L
A
Site 27
S219
A
N
K
L
A
A
P
S
V
S
H
V
S
P
R
Site 28
S221
K
L
A
A
P
S
V
S
H
V
S
P
R
K
N
Site 29
S224
A
P
S
V
S
H
V
S
P
R
K
N
P
S
V
Site 30
S230
V
S
P
R
K
N
P
S
V
V
I
K
P
E
A
Site 31
S239
V
I
K
P
E
A
C
S
P
Q
F
G
K
T
S
Site 32
T245
C
S
P
Q
F
G
K
T
S
F
P
T
K
E
S
Site 33
S246
S
P
Q
F
G
K
T
S
F
P
T
K
E
S
F
Site 34
S252
T
S
F
P
T
K
E
S
F
S
A
N
M
S
L
Site 35
S254
F
P
T
K
E
S
F
S
A
N
M
S
L
P
H
Site 36
S258
E
S
F
S
A
N
M
S
L
P
H
P
C
Q
T
Site 37
T265
S
L
P
H
P
C
Q
T
E
S
G
Y
K
P
L
Site 38
S267
P
H
P
C
Q
T
E
S
G
Y
K
P
L
V
G
Site 39
S278
P
L
V
G
R
E
D
S
K
P
H
S
L
R
G
Site 40
S282
R
E
D
S
K
P
H
S
L
R
G
D
S
I
K
Site 41
S287
P
H
S
L
R
G
D
S
I
K
Q
E
E
A
Q
Site 42
S296
K
Q
E
E
A
Q
K
S
F
V
D
S
W
R
Q
Site 43
S300
A
Q
K
S
F
V
D
S
W
R
Q
R
S
N
T
Site 44
S305
V
D
S
W
R
Q
R
S
N
T
Q
G
S
I
L
Site 45
T307
S
W
R
Q
R
S
N
T
Q
G
S
I
L
I
N
Site 46
S335
S
L
C
H
L
L
S
S
S
S
E
S
P
A
G
Site 47
S337
C
H
L
L
S
S
S
S
E
S
P
A
G
T
P
Site 48
S339
L
L
S
S
S
S
E
S
P
A
G
T
P
L
Q
Site 49
T343
S
S
E
S
P
A
G
T
P
L
Q
P
P
G
F
Site 50
T362
A
G
M
S
G
L
R
T
T
G
S
Y
D
G
S
Site 51
T363
G
M
S
G
L
R
T
T
G
S
Y
D
G
S
F
Site 52
S365
S
G
L
R
T
T
G
S
Y
D
G
S
F
S
L
Site 53
Y366
G
L
R
T
T
G
S
Y
D
G
S
F
S
L
S
Site 54
S369
T
T
G
S
Y
D
G
S
F
S
L
S
A
L
R
Site 55
S371
G
S
Y
D
G
S
F
S
L
S
A
L
R
E
A
Site 56
S373
Y
D
G
S
F
S
L
S
A
L
R
E
A
Q
N
Site 57
S449
R
S
G
A
P
G
D
S
P
T
H
S
S
C
V
Site 58
T451
G
A
P
G
D
S
P
T
H
S
S
C
V
S
S
Site 59
S453
P
G
D
S
P
T
H
S
S
C
V
S
S
G
V
Site 60
S454
G
D
S
P
T
H
S
S
C
V
S
S
G
V
E
Site 61
S457
P
T
H
S
S
C
V
S
S
G
V
E
T
N
P
Site 62
S458
T
H
S
S
C
V
S
S
G
V
E
T
N
P
E
Site 63
T462
C
V
S
S
G
V
E
T
N
P
E
D
S
V
C
Site 64
S467
V
E
T
N
P
E
D
S
V
C
I
L
E
G
F
Site 65
S504
L
S
G
V
G
A
D
S
A
A
G
E
G
N
R
Site 66
S512
A
A
G
E
G
N
R
S
L
V
H
R
L
S
D
Site 67
S518
R
S
L
V
H
R
L
S
D
G
D
M
T
S
A
Site 68
T523
R
L
S
D
G
D
M
T
S
A
L
R
G
V
A
Site 69
S524
L
S
D
G
D
M
T
S
A
L
R
G
V
A
D
Site 70
S576
V
K
L
A
E
N
T
S
C
D
F
L
P
R
F
Site 71
S595
Q
V
L
P
K
C
L
S
P
E
T
P
L
P
S
Site 72
Y636
G
C
L
L
L
L
L
Y
M
Y
I
T
S
R
P
Site 73
T650
P
D
R
V
A
L
E
T
Q
W
L
Q
L
E
Q
Site 74
T676
Q
S
P
L
P
P
V
T
G
S
N
C
Q
C
N
Site 75
S678
P
L
P
P
V
T
G
S
N
C
Q
C
N
V
E
Site 76
T700
M
L
H
R
Q
W
L
T
V
R
R
A
G
G
P
Site 77
T716
R
T
D
Q
Q
R
R
T
V
R
C
L
R
D
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation