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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP1R13L
Full Name:
RelA-associated inhibitor
Alias:
IASPP; IASPP gene; NKIP1; RAI; RelA-associated inhibitor: Inhibitor of ASPP protein: PPP1R13B-like protein: NFkB-interacting protein 1: cDNA FLJ26816 fis, clone PRS06437
Type:
Transcription, coactivator/corepressor; Apoptosis
Mass (Da):
89091
Number AA:
828
UniProt ID:
Q8WUF5
International Prot ID:
IPI00439948
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003714
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
D
S
E
A
F
Q
S
A
R
D
F
L
D
M
Site 2
T43
A
A
K
V
D
E
L
T
K
Q
L
E
S
L
W
Site 3
S48
E
L
T
K
Q
L
E
S
L
W
S
D
S
P
A
Site 4
S51
K
Q
L
E
S
L
W
S
D
S
P
A
P
P
G
Site 5
S53
L
E
S
L
W
S
D
S
P
A
P
P
G
P
Q
Site 6
S65
G
P
Q
A
G
P
P
S
R
P
P
R
Y
S
S
Site 7
Y70
P
P
S
R
P
P
R
Y
S
S
S
S
I
P
E
Site 8
S71
P
S
R
P
P
R
Y
S
S
S
S
I
P
E
P
Site 9
S72
S
R
P
P
R
Y
S
S
S
S
I
P
E
P
F
Site 10
S73
R
P
P
R
Y
S
S
S
S
I
P
E
P
F
G
Site 11
S74
P
P
R
Y
S
S
S
S
I
P
E
P
F
G
S
Site 12
S81
S
I
P
E
P
F
G
S
R
G
S
P
R
K
A
Site 13
S84
E
P
F
G
S
R
G
S
P
R
K
A
A
T
D
Site 14
T90
G
S
P
R
K
A
A
T
D
G
A
D
T
P
F
Site 15
T95
A
A
T
D
G
A
D
T
P
F
G
R
S
E
S
Site 16
S100
A
D
T
P
F
G
R
S
E
S
A
P
T
L
H
Site 17
S102
T
P
F
G
R
S
E
S
A
P
T
L
H
P
Y
Site 18
T105
G
R
S
E
S
A
P
T
L
H
P
Y
S
P
L
Site 19
Y109
S
A
P
T
L
H
P
Y
S
P
L
S
P
K
G
Site 20
S110
A
P
T
L
H
P
Y
S
P
L
S
P
K
G
R
Site 21
S113
L
H
P
Y
S
P
L
S
P
K
G
R
P
S
S
Site 22
S119
L
S
P
K
G
R
P
S
S
P
R
T
P
L
Y
Site 23
S120
S
P
K
G
R
P
S
S
P
R
T
P
L
Y
L
Site 24
T123
G
R
P
S
S
P
R
T
P
L
Y
L
Q
P
D
Site 25
Y126
S
S
P
R
T
P
L
Y
L
Q
P
D
A
Y
G
Site 26
Y132
L
Y
L
Q
P
D
A
Y
G
S
L
D
R
A
T
Site 27
S134
L
Q
P
D
A
Y
G
S
L
D
R
A
T
S
P
Site 28
T139
Y
G
S
L
D
R
A
T
S
P
R
P
R
A
F
Site 29
S140
G
S
L
D
R
A
T
S
P
R
P
R
A
F
D
Site 30
S151
R
A
F
D
G
A
G
S
S
L
G
R
A
P
S
Site 31
S152
A
F
D
G
A
G
S
S
L
G
R
A
P
S
P
Site 32
S158
S
S
L
G
R
A
P
S
P
R
P
G
P
G
P
Site 33
T173
L
R
Q
Q
G
P
P
T
P
F
D
F
L
G
R
Site 34
S183
D
F
L
G
R
A
G
S
P
R
G
S
P
L
A
Site 35
S187
R
A
G
S
P
R
G
S
P
L
A
E
G
P
Q
Site 36
S203
F
F
P
E
R
G
P
S
P
R
P
P
A
T
A
Site 37
T209
P
S
P
R
P
P
A
T
A
Y
D
A
P
A
S
Site 38
Y211
P
R
P
P
A
T
A
Y
D
A
P
A
S
A
F
Site 39
S220
A
P
A
S
A
F
G
S
S
L
L
G
S
G
G
Site 40
S225
F
G
S
S
L
L
G
S
G
G
S
A
F
A
P
Site 41
T241
L
R
A
Q
D
D
L
T
L
R
R
R
P
P
K
Site 42
Y259
E
S
D
L
D
V
A
Y
E
K
K
P
S
Q
T
Site 43
S264
V
A
Y
E
K
K
P
S
Q
T
A
S
Y
E
R
Site 44
S268
K
K
P
S
Q
T
A
S
Y
E
R
L
D
V
F
Site 45
Y269
K
P
S
Q
T
A
S
Y
E
R
L
D
V
F
A
Site 46
S280
D
V
F
A
R
P
A
S
P
S
L
Q
L
L
P
Site 47
S282
F
A
R
P
A
S
P
S
L
Q
L
L
P
W
R
Site 48
S291
Q
L
L
P
W
R
E
S
S
L
D
G
L
G
G
Site 49
S292
L
L
P
W
R
E
S
S
L
D
G
L
G
G
T
Site 50
T305
G
T
G
K
D
N
L
T
S
A
T
L
P
R
N
Site 51
T308
K
D
N
L
T
S
A
T
L
P
R
N
Y
K
V
Site 52
Y313
S
A
T
L
P
R
N
Y
K
V
S
P
L
A
S
Site 53
S316
L
P
R
N
Y
K
V
S
P
L
A
S
D
R
R
Site 54
S320
Y
K
V
S
P
L
A
S
D
R
R
S
D
A
G
Site 55
S324
P
L
A
S
D
R
R
S
D
A
G
S
Y
R
R
Site 56
S328
D
R
R
S
D
A
G
S
Y
R
R
S
L
G
S
Site 57
Y329
R
R
S
D
A
G
S
Y
R
R
S
L
G
S
A
Site 58
S332
D
A
G
S
Y
R
R
S
L
G
S
A
G
P
S
Site 59
S335
S
Y
R
R
S
L
G
S
A
G
P
S
G
T
L
Site 60
S339
S
L
G
S
A
G
P
S
G
T
L
P
R
S
W
Site 61
T341
G
S
A
G
P
S
G
T
L
P
R
S
W
Q
P
Site 62
S345
P
S
G
T
L
P
R
S
W
Q
P
V
S
R
I
Site 63
S350
P
R
S
W
Q
P
V
S
R
I
P
M
P
P
S
Site 64
S357
S
R
I
P
M
P
P
S
S
P
Q
P
R
G
A
Site 65
S358
R
I
P
M
P
P
S
S
P
Q
P
R
G
A
P
Site 66
S373
R
Q
R
P
I
P
L
S
M
I
F
K
L
Q
N
Site 67
S388
A
F
W
E
H
G
A
S
R
A
M
L
P
G
S
Site 68
S395
S
R
A
M
L
P
G
S
P
L
F
T
R
A
P
Site 69
T399
L
P
G
S
P
L
F
T
R
A
P
P
P
K
L
Site 70
S418
Q
P
Q
P
Q
P
Q
S
Q
P
Q
P
Q
L
P
Site 71
T430
Q
L
P
P
Q
P
Q
T
Q
P
Q
T
P
T
P
Site 72
T434
Q
P
Q
T
Q
P
Q
T
P
T
P
A
P
Q
H
Site 73
T436
Q
T
Q
P
Q
T
P
T
P
A
P
Q
H
P
Q
Site 74
T445
A
P
Q
H
P
Q
Q
T
W
P
P
V
N
E
G
Site 75
T458
E
G
P
P
K
P
P
T
E
L
E
P
E
P
E
Site 76
S489
G
P
V
A
R
P
L
S
P
T
R
L
Q
P
A
Site 77
T491
V
A
R
P
L
S
P
T
R
L
Q
P
A
L
P
Site 78
S503
A
L
P
P
E
A
Q
S
V
P
E
L
E
E
V
Site 79
S526
R
P
L
K
R
R
G
S
M
E
Q
A
P
A
V
Site 80
Y543
P
P
T
H
K
K
Q
Y
Q
Q
I
I
S
R
L
Site 81
S567
G
G
P
E
P
E
L
S
P
I
T
E
G
S
E
Site 82
S573
L
S
P
I
T
E
G
S
E
A
R
A
G
P
P
Site 83
S594
P
I
P
P
P
A
P
S
Q
S
S
P
P
E
Q
Site 84
S596
P
P
P
A
P
S
Q
S
S
P
P
E
Q
P
Q
Site 85
S597
P
P
A
P
S
Q
S
S
P
P
E
Q
P
Q
S
Site 86
S604
S
P
P
E
Q
P
Q
S
M
E
M
R
S
V
L
Site 87
S609
P
Q
S
M
E
M
R
S
V
L
R
K
A
G
S
Site 88
S616
S
V
L
R
K
A
G
S
P
R
K
A
R
R
A
Site 89
S654
V
K
E
M
N
D
P
S
Q
P
N
E
E
G
I
Site 90
T662
Q
P
N
E
E
G
I
T
A
L
H
N
A
I
C
Site 91
S688
T
A
G
A
N
V
N
S
P
D
S
H
G
W
T
Site 92
S691
A
N
V
N
S
P
D
S
H
G
W
T
P
L
H
Site 93
T695
S
P
D
S
H
G
W
T
P
L
H
C
A
A
S
Site 94
T729
T
T
L
S
D
G
A
T
A
F
E
K
C
D
P
Site 95
Y737
A
F
E
K
C
D
P
Y
R
E
G
Y
A
D
C
Site 96
Y741
C
D
P
Y
R
E
G
Y
A
D
C
A
T
Y
L
Site 97
T746
E
G
Y
A
D
C
A
T
Y
L
A
D
V
E
Q
Site 98
Y747
G
Y
A
D
C
A
T
Y
L
A
D
V
E
Q
S
Site 99
Y769
A
V
Y
A
L
W
D
Y
S
A
E
F
G
D
E
Site 100
S770
V
Y
A
L
W
D
Y
S
A
E
F
G
D
E
L
Site 101
S778
A
E
F
G
D
E
L
S
F
R
E
G
E
S
V
Site 102
S784
L
S
F
R
E
G
E
S
V
T
V
L
R
R
D
Site 103
T786
F
R
E
G
E
S
V
T
V
L
R
R
D
G
P
Site 104
Y809
A
L
H
G
Q
E
G
Y
V
P
R
N
Y
F
G
Site 105
Y814
E
G
Y
V
P
R
N
Y
F
G
L
F
P
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation