PhosphoNET

           
Protein Info 
   
Short Name:  BRSK1
Full Name:  BR serine/threonine-protein kinase 1
Alias:  BR serine/threonine kinase 1; EC 2.7.11.1; KIAA1811; SAD1; SAD1 kinase; SAD1A
Type:  Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; CAMK group; CAMKL family; BRSK subfamily
Mass (Da):  86753
Number AA:  794
UniProt ID:  Q8TDC3
International Prot ID:  IPI00148020
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030054  GO:0005737  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0000287  GO:0004674 PhosphoSite+ KinaseNET
Biological Process:  GO:0031572  GO:0030010  GO:0030182 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S13TLGKGPESPDGDVSV
Site 2S19ESPDGDVSVPERKDE
Site 3Y46ERGRHAQYVGPYRLE
Site 4T55GPYRLEKTLGKGQTG
Site 5S89NREKLSESVLMKVER
Site 6Y116VLKLHDVYENKKYLY
Site 7Y121DVYENKKYLYLVLEH
Site 8Y123YENKKYLYLVLEHVS
Site 9Y137SGGELFDYLVKKGRL
Site 10T145LVKKGRLTPKEARKF
Site 11T205VGDSLLETSCGSPHY
Site 12S206GDSLLETSCGSPHYA
Site 13S209LLETSCGSPHYACPE
Site 14Y212TSCGSPHYACPEVIK
Site 15Y223EVIKGEKYDGRRADM
Site 16S291VEPEKRLSLEQIQKH
Site 17Y301QIQKHPWYLGGKHEP
Site 18S324GRRVAMRSLPSNGEL
Site 19S327VAMRSLPSNGELDPD
Site 20S341DVLESMASLGCFRDR
Site 21S357RLHRELRSEEENQEK
Site 22Y367ENQEKMIYYLLLDRK
Site 23Y377LLDRKERYPSCEDQD
Site 24S379DRKERYPSCEDQDLP
Site 25S400PPRKRVDSPMLSRHG
Site 26S404RVDSPMLSRHGKRRP
Site 27S415KRRPERKSMEVLSIT
Site 28S420RKSMEVLSITDAGGG
Site 29S429TDAGGGGSPVPTRRA
Site 30T433GGGSPVPTRRALEMA
Site 31S443ALEMAQHSQRSRSVS
Site 32S446MAQHSQRSRSVSGAS
Site 33S448QHSQRSRSVSGASTG
Site 34S450SQRSRSVSGASTGLS
Site 35S453SRSVSGASTGLSSSP
Site 36T454RSVSGASTGLSSSPL
Site 37S457SGASTGLSSSPLSSP
Site 38S458GASTGLSSSPLSSPR
Site 39S459ASTGLSSSPLSSPRS
Site 40S462GLSSSPLSSPRSPVF
Site 41S463LSSSPLSSPRSPVFS
Site 42S466SPLSSPRSPVFSFSP
Site 43S470SPRSPVFSFSPEPGA
Site 44S472RSPVFSFSPEPGAGD
Site 45S486DEARGGGSPTSKTQT
Site 46T488ARGGGSPTSKTQTLP
Site 47S489RGGGSPTSKTQTLPS
Site 48T491GGSPTSKTQTLPSRG
Site 49T493SPTSKTQTLPSRGPR
Site 50S496SKTQTLPSRGPRGGG
Site 51S512GEQPPPPSARSTPLP
Site 52S515PPPPSARSTPLPGPP
Site 53T516PPPSARSTPLPGPPG
Site 54S524PLPGPPGSPRSSGGT
Site 55S527GPPGSPRSSGGTPLH
Site 56S528PPGSPRSSGGTPLHS
Site 57T531SPRSSGGTPLHSPLH
Site 58S535SGGTPLHSPLHTPRA
Site 59T539PLHSPLHTPRASPTG
Site 60S543PLHTPRASPTGTPGT
Site 61T545HTPRASPTGTPGTTP
Site 62T547PRASPTGTPGTTPPP
Site 63T550SPTGTPGTTPPPSPG
Site 64T551PTGTPGTTPPPSPGG
Site 65S555PGTTPPPSPGGGVGG
Site 66S567VGGAAWRSRLNSIRN
Site 67S571AWRSRLNSIRNSFLG
Site 68S575RLNSIRNSFLGSPRF
Site 69S579IRNSFLGSPRFHRRK
Site 70S597PTAEEMSSLTPESSP
Site 71T599AEEMSSLTPESSPEL
Site 72S602MSSLTPESSPELAKR
Site 73S603SSLTPESSPELAKRS
Site 74S617SWFGNFISLDKEEQI
Site 75S653SIPSLSHSVLSQTSF
Site 76S656SLSHSVLSQTSFRAE
Site 77S659HSVLSQTSFRAEYKA
Site 78Y664QTSFRAEYKASGGPS
Site 79S667FRAEYKASGGPSVFQ
Site 80S671YKASGGPSVFQKPVR
Site 81S684VRFQVDISSSEGPEP
Site 82S685RFQVDISSSEGPEPS
Site 83S686FQVDISSSEGPEPSP
Site 84S692SSEGPEPSPRRDGSG
Site 85S698PSPRRDGSGGGGIYS
Site 86S712SVTFTLISGPSRRFK
Site 87S715FTLISGPSRRFKRVV
Site 88S731TIQAQLLSTHDQPSV
Site 89T750DEKNGAQTRPAGAPP
Site 90S759PAGAPPRSLQPPPGR
Site 91S772GRPDPELSSSPRRGP
Site 92S773RPDPELSSSPRRGPP
Site 93S774PDPELSSSPRRGPPK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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