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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STT3B
Full Name:
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B
Alias:
Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit STT3B; FLJ90106; Oligosaccharyl transferase subunit STT3B; SIMP; Source of immunodominant MHC associated peptides; Source of immunodominant MHC-associated peptides; Source of immunodominant MHC-associated peptides homologue; STT3, subunit of the oligosaccharyltransferase complex, B; STT3-B
Type:
EC 2.4.1.119; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; Transferase
Mass (Da):
93674
Number AA:
826
UniProt ID:
Q8TCJ2
International Prot ID:
IPI00152377
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0008250
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0004579
GO:0005515
GO:0004579
PhosphoSite+
KinaseNET
Biological Process:
GO:0018279
GO:0006486
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
E
P
S
A
P
E
S
K
H
K
S
S
L
N
Site 2
S13
A
P
E
S
K
H
K
S
S
L
N
S
S
P
W
Site 3
S14
P
E
S
K
H
K
S
S
L
N
S
S
P
W
S
Site 4
S17
K
H
K
S
S
L
N
S
S
P
W
S
G
L
M
Site 5
S18
H
K
S
S
L
N
S
S
P
W
S
G
L
M
A
Site 6
S21
S
L
N
S
S
P
W
S
G
L
M
A
L
G
N
Site 7
S29
G
L
M
A
L
G
N
S
R
H
G
H
H
G
P
Site 8
S59
K
P
A
P
A
G
L
S
G
G
L
S
Q
P
A
Site 9
S63
A
G
L
S
G
G
L
S
Q
P
A
G
W
Q
S
Site 10
Y120
H
L
A
S
H
G
F
Y
E
F
L
N
W
F
D
Site 11
Y132
W
F
D
E
R
A
W
Y
P
L
G
R
I
V
G
Site 12
S215
V
P
G
Y
I
S
R
S
V
A
G
S
F
D
N
Site 13
S219
I
S
R
S
V
A
G
S
F
D
N
E
G
I
A
Site 14
Y291
Q
R
Y
S
K
R
V
Y
I
A
Y
S
T
F
Y
Site 15
S319
G
F
Q
P
I
R
T
S
E
H
M
A
A
A
G
Site 16
Y339
Q
A
Y
A
F
L
Q
Y
L
R
D
R
L
T
K
Site 17
T345
Q
Y
L
R
D
R
L
T
K
Q
E
F
Q
T
L
Site 18
Y376
I
Y
L
T
Y
T
G
Y
I
A
P
W
S
G
R
Site 19
Y385
A
P
W
S
G
R
F
Y
S
L
W
D
T
G
Y
Site 20
T409
S
V
S
E
H
Q
P
T
T
W
V
S
F
F
F
Site 21
S498
E
N
P
P
V
E
D
S
S
D
E
D
D
K
R
Site 22
S499
N
P
P
V
E
D
S
S
D
E
D
D
K
R
N
Site 23
Y511
K
R
N
Q
G
N
L
Y
D
K
A
G
K
V
R
Site 24
T527
H
A
T
E
Q
E
K
T
E
E
G
L
G
P
N
Site 25
S566
S
N
A
Y
S
S
P
S
V
V
L
A
S
Y
N
Site 26
Y572
P
S
V
V
L
A
S
Y
N
H
D
G
T
R
N
Site 27
Y588
L
D
D
F
R
E
A
Y
F
W
L
R
Q
N
T
Site 28
S639
A
L
V
G
K
A
M
S
S
N
E
T
A
A
Y
Site 29
S640
L
V
G
K
A
M
S
S
N
E
T
A
A
Y
K
Site 30
T643
K
A
M
S
S
N
E
T
A
A
Y
K
I
M
R
Site 31
Y646
S
S
N
E
T
A
A
Y
K
I
M
R
T
L
D
Site 32
S693
H
P
K
D
I
R
E
S
D
Y
F
T
P
Q
G
Site 33
Y695
K
D
I
R
E
S
D
Y
F
T
P
Q
G
E
F
Site 34
T697
I
R
E
S
D
Y
F
T
P
Q
G
E
F
R
V
Site 35
Y723
L
M
Y
K
M
S
Y
Y
R
F
G
E
M
Q
L
Site 36
T734
E
M
Q
L
D
F
R
T
P
P
G
F
D
R
T
Site 37
T741
T
P
P
G
F
D
R
T
R
N
A
E
I
G
N
Site 38
T761
K
H
L
E
E
A
F
T
S
E
H
W
L
V
R
Site 39
Y770
E
H
W
L
V
R
I
Y
K
V
K
A
P
D
N
Site 40
T780
K
A
P
D
N
R
E
T
L
D
H
K
P
R
V
Site 41
T788
L
D
H
K
P
R
V
T
N
I
F
P
K
Q
K
Site 42
Y796
N
I
F
P
K
Q
K
Y
L
S
K
K
T
T
K
Site 43
T801
Q
K
Y
L
S
K
K
T
T
K
R
K
R
G
Y
Site 44
T802
K
Y
L
S
K
K
T
T
K
R
K
R
G
Y
I
Site 45
Y808
T
T
K
R
K
R
G
Y
I
K
N
K
L
V
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation