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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF280C
Full Name:
Zinc finger protein 280C
Alias:
SUHW3; Suppressor of hairy wing homolog 3; Suppressor of hairy wing homologue 3; ZNF633
Type:
Transcription factor
Mass (Da):
83096
Number AA:
737
UniProt ID:
Q8ND82
International Prot ID:
IPI00183642
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S59
S
S
S
K
P
A
I
S
N
I
L
N
R
G
H
Site 2
S67
N
I
L
N
R
G
H
S
S
S
S
S
K
G
I
Site 3
S68
I
L
N
R
G
H
S
S
S
S
S
K
G
I
K
Site 4
S69
L
N
R
G
H
S
S
S
S
S
K
G
I
K
S
Site 5
S71
R
G
H
S
S
S
S
S
K
G
I
K
S
E
P
Site 6
S76
S
S
S
K
G
I
K
S
E
P
H
S
P
G
I
Site 7
S80
G
I
K
S
E
P
H
S
P
G
I
P
E
I
F
Site 8
T89
G
I
P
E
I
F
R
T
A
S
Q
R
C
R
D
Site 9
S91
P
E
I
F
R
T
A
S
Q
R
C
R
D
P
P
Site 10
S99
Q
R
C
R
D
P
P
S
N
P
V
A
A
S
P
Site 11
S105
P
S
N
P
V
A
A
S
P
R
F
H
L
V
S
Site 12
S112
S
P
R
F
H
L
V
S
K
S
S
Q
S
S
V
Site 13
S114
R
F
H
L
V
S
K
S
S
Q
S
S
V
T
V
Site 14
S115
F
H
L
V
S
K
S
S
Q
S
S
V
T
V
E
Site 15
S118
V
S
K
S
S
Q
S
S
V
T
V
E
N
A
S
Site 16
T120
K
S
S
Q
S
S
V
T
V
E
N
A
S
K
P
Site 17
T130
N
A
S
K
P
D
F
T
K
N
S
Q
V
G
S
Site 18
S133
K
P
D
F
T
K
N
S
Q
V
G
S
D
N
S
Site 19
S137
T
K
N
S
Q
V
G
S
D
N
S
S
I
L
L
Site 20
S140
S
Q
V
G
S
D
N
S
S
I
L
L
F
D
S
Site 21
S141
Q
V
G
S
D
N
S
S
I
L
L
F
D
S
T
Site 22
S147
S
S
I
L
L
F
D
S
T
Q
E
S
L
P
P
Site 23
T148
S
I
L
L
F
D
S
T
Q
E
S
L
P
P
S
Site 24
S151
L
F
D
S
T
Q
E
S
L
P
P
S
Q
D
I
Site 25
S155
T
Q
E
S
L
P
P
S
Q
D
I
P
A
I
F
Site 26
Y171
E
G
M
K
N
T
S
Y
V
L
K
H
P
S
T
Site 27
S177
S
Y
V
L
K
H
P
S
T
S
K
V
N
S
V
Site 28
T178
Y
V
L
K
H
P
S
T
S
K
V
N
S
V
T
Site 29
S179
V
L
K
H
P
S
T
S
K
V
N
S
V
T
P
Site 30
S183
P
S
T
S
K
V
N
S
V
T
P
K
K
P
K
Site 31
T185
T
S
K
V
N
S
V
T
P
K
K
P
K
T
S
Site 32
T191
V
T
P
K
K
P
K
T
S
E
D
V
P
Q
I
Site 33
S203
P
Q
I
N
P
S
T
S
L
P
L
I
G
S
P
Site 34
S209
T
S
L
P
L
I
G
S
P
P
V
T
S
S
Q
Site 35
S214
I
G
S
P
P
V
T
S
S
Q
V
M
L
S
K
Site 36
S215
G
S
P
P
V
T
S
S
Q
V
M
L
S
K
G
Site 37
S220
T
S
S
Q
V
M
L
S
K
G
T
N
T
S
S
Site 38
T223
Q
V
M
L
S
K
G
T
N
T
S
S
P
Y
D
Site 39
S227
S
K
G
T
N
T
S
S
P
Y
D
A
G
A
D
Site 40
Y235
P
Y
D
A
G
A
D
Y
L
R
A
C
P
K
C
Site 41
Y254
N
L
L
D
P
L
K
Y
H
M
K
H
C
C
P
Site 42
S274
F
L
G
V
I
V
K
S
E
R
P
C
D
E
D
Site 43
T283
R
P
C
D
E
D
K
T
D
S
E
T
G
K
L
Site 44
S285
C
D
E
D
K
T
D
S
E
T
G
K
L
I
M
Site 45
Y298
I
M
L
V
N
E
F
Y
Y
G
R
H
E
G
V
Site 46
Y299
M
L
V
N
E
F
Y
Y
G
R
H
E
G
V
T
Site 47
T306
Y
G
R
H
E
G
V
T
E
K
E
P
K
T
Y
Site 48
T312
V
T
E
K
E
P
K
T
Y
T
T
F
K
C
F
Site 49
Y313
T
E
K
E
P
K
T
Y
T
T
F
K
C
F
S
Site 50
T315
K
E
P
K
T
Y
T
T
F
K
C
F
S
C
S
Site 51
T375
L
Q
C
H
I
E
S
T
H
T
P
H
E
F
S
Site 52
T377
C
H
I
E
S
T
H
T
P
H
E
F
S
T
I
Site 53
T405
L
L
Q
H
M
K
D
T
H
K
P
G
E
M
P
Site 54
Y413
H
K
P
G
E
M
P
Y
V
C
Q
V
C
Q
F
Site 55
S422
C
Q
V
C
Q
F
R
S
S
T
F
S
D
V
E
Site 56
S423
Q
V
C
Q
F
R
S
S
T
F
S
D
V
E
A
Site 57
T424
V
C
Q
F
R
S
S
T
F
S
D
V
E
A
H
Site 58
S426
Q
F
R
S
S
T
F
S
D
V
E
A
H
F
R
Site 59
Y461
A
T
P
Y
M
N
H
Y
M
K
H
Q
K
K
G
Site 60
T481
K
C
R
L
Q
F
L
T
S
K
E
K
A
E
H
Site 61
S482
C
R
L
Q
F
L
T
S
K
E
K
A
E
H
K
Site 62
T494
E
H
K
A
Q
H
R
T
F
I
K
P
K
E
L
Site 63
S515
A
K
V
T
I
R
A
S
L
G
P
L
Q
S
K
Site 64
T525
P
L
Q
S
K
L
P
T
A
P
F
G
C
A
P
Site 65
T540
G
T
S
F
L
Q
V
T
P
P
T
S
Q
N
T
Site 66
T543
F
L
Q
V
T
P
P
T
S
Q
N
T
T
A
R
Site 67
S544
L
Q
V
T
P
P
T
S
Q
N
T
T
A
R
N
Site 68
T548
P
P
T
S
Q
N
T
T
A
R
N
P
R
K
S
Site 69
S555
T
A
R
N
P
R
K
S
N
A
S
R
S
K
T
Site 70
S558
N
P
R
K
S
N
A
S
R
S
K
T
S
K
L
Site 71
S560
R
K
S
N
A
S
R
S
K
T
S
K
L
H
A
Site 72
T562
S
N
A
S
R
S
K
T
S
K
L
H
A
T
T
Site 73
T568
K
T
S
K
L
H
A
T
T
S
T
A
S
K
V
Site 74
S570
S
K
L
H
A
T
T
S
T
A
S
K
V
N
T
Site 75
T577
S
T
A
S
K
V
N
T
S
K
P
R
G
R
I
Site 76
S587
P
R
G
R
I
A
K
S
K
A
K
P
S
Y
K
Site 77
Y593
K
S
K
A
K
P
S
Y
K
Q
K
R
Q
R
N
Site 78
S606
R
N
R
K
N
K
M
S
L
A
L
K
N
I
R
Site 79
S696
K
C
D
F
L
A
D
S
S
G
L
D
R
M
A
Site 80
S697
C
D
F
L
A
D
S
S
G
L
D
R
M
A
K
Site 81
S707
D
R
M
A
K
H
L
S
Q
R
K
T
H
T
C
Site 82
T711
K
H
L
S
Q
R
K
T
H
T
C
Q
V
I
I
Site 83
S722
Q
V
I
I
E
N
V
S
K
S
T
S
T
S
E
Site 84
S724
I
I
E
N
V
S
K
S
T
S
T
S
E
P
T
Site 85
T725
I
E
N
V
S
K
S
T
S
T
S
E
P
T
T
Site 86
S726
E
N
V
S
K
S
T
S
T
S
E
P
T
T
G
Site 87
T727
N
V
S
K
S
T
S
T
S
E
P
T
T
G
C
Site 88
S728
V
S
K
S
T
S
T
S
E
P
T
T
G
C
S
Site 89
T731
S
T
S
T
S
E
P
T
T
G
C
S
L
K
_
Site 90
T732
T
S
T
S
E
P
T
T
G
C
S
L
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation