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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RNF214
Full Name:
RING finger protein 214
Alias:
DKFZp547C195; ring finger 214; ring finger protein 214
Type:
Mass (Da):
77667
Number AA:
703
UniProt ID:
Q8ND24
International Prot ID:
IPI00742996
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
G
V
V
A
N
A
P
S
P
P
E
S
S
S
L
Site 2
S19
N
A
P
S
P
P
E
S
S
S
L
C
A
S
K
Site 3
S20
A
P
S
P
P
E
S
S
S
L
C
A
S
K
S
Site 4
S21
P
S
P
P
E
S
S
S
L
C
A
S
K
S
D
Site 5
S25
E
S
S
S
L
C
A
S
K
S
D
E
G
L
P
Site 6
S27
S
S
L
C
A
S
K
S
D
E
G
L
P
D
G
Site 7
S36
E
G
L
P
D
G
L
S
T
K
D
S
A
Q
K
Site 8
S40
D
G
L
S
T
K
D
S
A
Q
K
Q
K
N
S
Site 9
S47
S
A
Q
K
Q
K
N
S
P
L
L
S
V
S
S
Site 10
S51
Q
K
N
S
P
L
L
S
V
S
S
Q
T
I
T
Site 11
S53
N
S
P
L
L
S
V
S
S
Q
T
I
T
K
E
Site 12
S54
S
P
L
L
S
V
S
S
Q
T
I
T
K
E
N
Site 13
T56
L
L
S
V
S
S
Q
T
I
T
K
E
N
N
R
Site 14
T58
S
V
S
S
Q
T
I
T
K
E
N
N
R
N
V
Site 15
S70
R
N
V
H
L
E
H
S
E
Q
N
P
G
S
S
Site 16
S76
H
S
E
Q
N
P
G
S
S
A
G
D
T
S
A
Site 17
T81
P
G
S
S
A
G
D
T
S
A
A
H
Q
V
V
Site 18
S103
T
A
L
C
L
S
G
S
G
S
Q
S
D
L
K
Site 19
S105
L
C
L
S
G
S
G
S
Q
S
D
L
K
D
V
Site 20
S107
L
S
G
S
G
S
Q
S
D
L
K
D
V
A
S
Site 21
S114
S
D
L
K
D
V
A
S
T
A
G
E
E
G
D
Site 22
T122
T
A
G
E
E
G
D
T
S
L
R
E
S
L
H
Site 23
S123
A
G
E
E
G
D
T
S
L
R
E
S
L
H
P
Site 24
S127
G
D
T
S
L
R
E
S
L
H
P
V
T
R
S
Site 25
S134
S
L
H
P
V
T
R
S
L
K
A
G
C
H
T
Site 26
S146
C
H
T
K
Q
L
A
S
R
N
C
S
E
E
K
Site 27
S150
Q
L
A
S
R
N
C
S
E
E
K
S
P
Q
T
Site 28
S154
R
N
C
S
E
E
K
S
P
Q
T
S
I
L
K
Site 29
S158
E
E
K
S
P
Q
T
S
I
L
K
E
G
N
R
Site 30
T167
L
K
E
G
N
R
D
T
S
L
D
F
R
P
V
Site 31
S168
K
E
G
N
R
D
T
S
L
D
F
R
P
V
V
Site 32
S176
L
D
F
R
P
V
V
S
P
A
N
G
V
E
G
Site 33
S194
D
Q
D
D
D
Q
D
S
S
S
L
K
L
S
Q
Site 34
S195
Q
D
D
D
Q
D
S
S
S
L
K
L
S
Q
N
Site 35
S196
D
D
D
Q
D
S
S
S
L
K
L
S
Q
N
I
Site 36
S200
D
S
S
S
L
K
L
S
Q
N
I
A
V
Q
T
Site 37
T211
A
V
Q
T
D
F
K
T
A
D
S
E
V
N
T
Site 38
S214
T
D
F
K
T
A
D
S
E
V
N
T
D
Q
D
Site 39
T218
T
A
D
S
E
V
N
T
D
Q
D
I
E
K
N
Site 40
T231
K
N
L
D
K
M
M
T
E
R
T
L
L
K
E
Site 41
Y240
R
T
L
L
K
E
R
Y
Q
E
V
L
D
K
Q
Site 42
T283
L
K
A
I
Q
D
V
T
I
K
R
E
E
T
K
Site 43
T289
V
T
I
K
R
E
E
T
K
K
K
I
E
K
E
Site 44
S355
A
W
K
A
E
I
L
S
L
E
S
R
K
E
L
Site 45
T379
K
E
A
E
L
H
L
T
Y
L
K
S
T
P
P
Site 46
Y380
E
A
E
L
H
L
T
Y
L
K
S
T
P
P
T
Site 47
S383
L
H
L
T
Y
L
K
S
T
P
P
T
L
E
T
Site 48
T384
H
L
T
Y
L
K
S
T
P
P
T
L
E
T
V
Site 49
T387
Y
L
K
S
T
P
P
T
L
E
T
V
R
S
K
Site 50
T390
S
T
P
P
T
L
E
T
V
R
S
K
Q
E
W
Site 51
S393
P
T
L
E
T
V
R
S
K
Q
E
W
E
T
R
Site 52
T399
R
S
K
Q
E
W
E
T
R
L
N
G
V
R
I
Site 53
S430
R
N
G
A
K
L
S
S
L
P
Q
I
P
T
P
Site 54
T436
S
S
L
P
Q
I
P
T
P
T
L
P
P
P
P
Site 55
T438
L
P
Q
I
P
T
P
T
L
P
P
P
P
S
E
Site 56
S444
P
T
L
P
P
P
P
S
E
T
D
F
M
L
Q
Site 57
S458
Q
V
F
Q
P
S
P
S
L
A
P
R
M
P
F
Site 58
S478
T
M
P
M
V
M
P
S
A
D
P
R
S
L
S
Site 59
S483
M
P
S
A
D
P
R
S
L
S
F
P
I
L
N
Site 60
S485
S
A
D
P
R
S
L
S
F
P
I
L
N
P
A
Site 61
S494
P
I
L
N
P
A
L
S
Q
P
S
Q
P
S
S
Site 62
S497
N
P
A
L
S
Q
P
S
Q
P
S
S
P
L
P
Site 63
S500
L
S
Q
P
S
Q
P
S
S
P
L
P
G
S
H
Site 64
S501
S
Q
P
S
Q
P
S
S
P
L
P
G
S
H
G
Site 65
S506
P
S
S
P
L
P
G
S
H
G
R
N
S
P
G
Site 66
S511
P
G
S
H
G
R
N
S
P
G
L
G
S
L
V
Site 67
S516
R
N
S
P
G
L
G
S
L
V
S
P
H
G
P
Site 68
S519
P
G
L
G
S
L
V
S
P
H
G
P
H
M
P
Site 69
S530
P
H
M
P
P
A
A
S
I
P
P
P
P
G
L
Site 70
T546
G
V
K
A
S
A
E
T
P
R
P
Q
P
V
D
Site 71
T564
K
I
L
E
K
L
L
T
R
F
P
Q
C
N
K
Site 72
T583
N
I
L
Q
Q
I
K
T
A
R
T
T
M
A
G
Site 73
T587
Q
I
K
T
A
R
T
T
M
A
G
L
T
M
E
Site 74
T614
H
E
R
V
A
A
S
T
Q
P
L
G
R
I
R
Site 75
S639
S
T
P
M
F
L
P
S
A
Q
V
S
Y
P
G
Site 76
S643
F
L
P
S
A
Q
V
S
Y
P
G
R
S
S
H
Site 77
Y644
L
P
S
A
Q
V
S
Y
P
G
R
S
S
H
A
Site 78
S649
V
S
Y
P
G
R
S
S
H
A
P
A
T
C
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation