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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STK11IP
Full Name:
Serine/threonine-protein kinase 11-interacting protein
Alias:
LKB1-interacting protein 1; Serine/threonine kinase 11-interacting protein: LKB1-interacting protein 1: Serine/threonine kinase 11-interacting protein: LKB1-interacting protein 1
Type:
Protein kinase, regulatory subunit
Mass (Da):
121461
Number AA:
1099
UniProt ID:
Q8N1F8
International Prot ID:
IPI00170934
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
P
Q
R
P
V
A
M
T
T
A
Q
R
D
S
L
Site 2
S19
M
T
T
A
Q
R
D
S
L
L
W
K
L
A
G
Site 3
S80
L
P
S
H
P
A
D
S
P
V
I
L
Q
L
Q
Site 4
S120
I
K
I
F
P
F
K
S
L
R
H
L
E
L
R
Site 5
T187
N
F
S
Y
N
A
L
T
A
L
D
S
S
L
R
Site 6
S205
A
L
R
F
L
N
L
S
H
N
Q
V
Q
D
C
Site 7
S228
E
L
H
H
L
D
I
S
Y
N
R
L
H
L
V
Site 8
Y229
L
H
H
L
D
I
S
Y
N
R
L
H
L
V
P
Site 9
S257
L
R
G
N
E
L
R
S
L
H
G
L
E
Q
L
Site 10
Y274
L
R
H
L
D
L
A
Y
N
L
L
E
G
H
R
Site 11
S284
L
E
G
H
R
E
L
S
P
L
W
L
L
A
E
Site 12
Y296
L
A
E
L
R
K
L
Y
L
E
G
N
P
L
W
Site 13
T312
H
P
E
H
R
A
A
T
A
Q
Y
L
S
P
R
Site 14
Y315
H
R
A
A
T
A
Q
Y
L
S
P
R
A
R
D
Site 15
S317
A
A
T
A
Q
Y
L
S
P
R
A
R
D
A
A
Site 16
T337
D
G
K
V
L
S
L
T
D
F
Q
T
H
T
S
Site 17
T341
L
S
L
T
D
F
Q
T
H
T
S
L
G
L
S
Site 18
S344
T
D
F
Q
T
H
T
S
L
G
L
S
P
M
G
Site 19
S348
T
H
T
S
L
G
L
S
P
M
G
P
P
L
P
Site 20
S360
P
L
P
W
P
V
G
S
T
P
E
T
S
G
G
Site 21
T361
L
P
W
P
V
G
S
T
P
E
T
S
G
G
P
Site 22
T364
P
V
G
S
T
P
E
T
S
G
G
P
D
L
S
Site 23
S365
V
G
S
T
P
E
T
S
G
G
P
D
L
S
D
Site 24
S371
T
S
G
G
P
D
L
S
D
S
L
S
S
G
G
Site 25
S373
G
G
P
D
L
S
D
S
L
S
S
G
G
V
V
Site 26
S375
P
D
L
S
D
S
L
S
S
G
G
V
V
T
Q
Site 27
S390
P
L
L
H
K
V
K
S
R
V
R
V
R
R
A
Site 28
S398
R
V
R
V
R
R
A
S
I
S
E
P
S
D
T
Site 29
S400
R
V
R
R
A
S
I
S
E
P
S
D
T
D
P
Site 30
S403
R
A
S
I
S
E
P
S
D
T
D
P
E
P
R
Site 31
T405
S
I
S
E
P
S
D
T
D
P
E
P
R
T
L
Site 32
T411
D
T
D
P
E
P
R
T
L
N
P
S
P
A
G
Site 33
S415
E
P
R
T
L
N
P
S
P
A
G
W
F
V
Q
Site 34
S432
P
E
L
E
L
M
S
S
F
R
E
R
F
G
R
Site 35
Y444
F
G
R
N
W
L
Q
Y
R
S
H
L
E
P
S
Site 36
S446
R
N
W
L
Q
Y
R
S
H
L
E
P
S
G
N
Site 37
S451
Y
R
S
H
L
E
P
S
G
N
P
L
P
A
T
Site 38
T458
S
G
N
P
L
P
A
T
P
T
T
S
A
P
S
Site 39
T460
N
P
L
P
A
T
P
T
T
S
A
P
S
A
P
Site 40
T461
P
L
P
A
T
P
T
T
S
A
P
S
A
P
P
Site 41
S462
L
P
A
T
P
T
T
S
A
P
S
A
P
P
A
Site 42
S465
T
P
T
T
S
A
P
S
A
P
P
A
S
S
Q
Site 43
S470
A
P
S
A
P
P
A
S
S
Q
G
P
D
T
A
Site 44
S471
P
S
A
P
P
A
S
S
Q
G
P
D
T
A
P
Site 45
T476
A
S
S
Q
G
P
D
T
A
P
R
P
S
P
P
Site 46
S481
P
D
T
A
P
R
P
S
P
P
Q
E
E
A
R
Site 47
S493
E
A
R
G
P
Q
E
S
P
Q
K
M
S
E
E
Site 48
T587
V
E
L
Q
A
A
R
T
L
E
R
L
E
L
Q
Site 49
S595
L
E
R
L
E
L
Q
S
L
E
A
A
E
I
E
Site 50
S610
P
E
A
Q
A
Q
R
S
P
R
P
T
G
S
D
Site 51
T614
A
Q
R
S
P
R
P
T
G
S
D
L
L
P
G
Site 52
S616
R
S
P
R
P
T
G
S
D
L
L
P
G
A
P
Site 53
S630
P
I
L
S
L
R
F
S
Y
I
C
P
D
R
Q
Site 54
Y631
I
L
S
L
R
F
S
Y
I
C
P
D
R
Q
L
Site 55
Y641
P
D
R
Q
L
R
R
Y
L
V
L
E
P
D
A
Site 56
T663
L
A
V
L
T
P
V
T
N
V
A
R
E
Q
L
Site 57
S701
E
P
R
M
G
L
D
S
E
E
G
W
R
P
L
Site 58
T712
W
R
P
L
F
Q
K
T
E
S
P
A
V
C
P
Site 59
S714
P
L
F
Q
K
T
E
S
P
A
V
C
P
N
C
Site 60
T735
L
L
A
V
S
R
G
T
P
N
R
E
R
K
Q
Site 61
S746
E
R
K
Q
G
E
Q
S
L
A
P
S
P
F
A
Site 62
S750
G
E
Q
S
L
A
P
S
P
F
A
S
P
V
C
Site 63
S754
L
A
P
S
P
F
A
S
P
V
C
H
P
P
G
Site 64
S772
H
L
D
R
A
K
N
S
P
P
Q
A
P
S
T
Site 65
S778
N
S
P
P
Q
A
P
S
T
R
D
H
G
S
W
Site 66
T779
S
P
P
Q
A
P
S
T
R
D
H
G
S
W
S
Site 67
S784
P
S
T
R
D
H
G
S
W
S
L
S
P
P
P
Site 68
S786
T
R
D
H
G
S
W
S
L
S
P
P
P
E
R
Site 69
S788
D
H
G
S
W
S
L
S
P
P
P
E
R
C
G
Site 70
S798
P
E
R
C
G
L
R
S
V
D
H
R
L
R
L
Site 71
Y848
V
V
S
D
R
R
L
Y
L
L
K
V
T
G
E
Site 72
S862
E
M
R
E
P
P
A
S
W
L
Q
L
T
L
A
Site 73
S921
E
L
L
D
V
L
Q
S
L
P
P
A
W
R
N
Site 74
S931
P
A
W
R
N
C
V
S
A
T
E
E
E
V
T
Site 75
T938
S
A
T
E
E
E
V
T
P
Q
H
R
L
W
P
Site 76
S951
W
P
L
L
E
K
D
S
S
L
E
A
R
Q
F
Site 77
S952
P
L
L
E
K
D
S
S
L
E
A
R
Q
F
F
Site 78
S993
L
D
E
D
A
A
G
S
P
A
E
P
S
P
P
Site 79
S998
A
G
S
P
A
E
P
S
P
P
A
A
S
G
E
Site 80
S1003
E
P
S
P
P
A
A
S
G
E
A
S
E
K
V
Site 81
S1007
P
A
A
S
G
E
A
S
E
K
V
P
P
S
G
Site 82
S1013
A
S
E
K
V
P
P
S
G
P
G
P
A
V
R
Site 83
S1029
R
E
Q
Q
P
L
S
S
L
S
S
V
L
L
Y
Site 84
S1031
Q
Q
P
L
S
S
L
S
S
V
L
L
Y
R
S
Site 85
Y1036
S
L
S
S
V
L
L
Y
R
S
A
P
E
D
L
Site 86
Y1048
E
D
L
R
L
L
F
Y
D
E
V
S
R
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation