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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1967
Full Name:
Protein KIAA1967
Alias:
DBC1; DBC-1; Deleted in breast cancer; Deleted in breast cancer gene 1 protein; DKFZp761M0817; K1967; NET35
Type:
Apoptosis protein
Mass (Da):
102902
Number AA:
923
UniProt ID:
Q8N163
International Prot ID:
IPI00783537
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
GO:0005634
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0008219
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
L
P
G
G
R
N
F
S
G
T
A
S
T
S
L
Site 2
T21
G
G
R
N
F
S
G
T
A
S
T
S
L
L
G
Site 3
S23
R
N
F
S
G
T
A
S
T
S
L
L
G
P
P
Site 4
S25
F
S
G
T
A
S
T
S
L
L
G
P
P
P
G
Site 5
T35
G
P
P
P
G
L
L
T
P
P
V
A
T
E
L
Site 6
S43
P
P
V
A
T
E
L
S
Q
N
A
R
H
L
Q
Site 7
T59
G
E
K
Q
R
V
F
T
G
I
V
T
S
L
H
Site 8
S117
A
V
K
V
Q
T
L
S
N
Q
P
L
L
K
S
Site 9
S124
S
N
Q
P
L
L
K
S
P
A
P
P
L
L
H
Site 10
S165
L
F
P
Q
K
P
L
S
L
F
Q
T
S
H
T
Site 11
T169
K
P
L
S
L
F
Q
T
S
H
T
L
H
L
S
Site 12
S170
P
L
S
L
F
Q
T
S
H
T
L
H
L
S
H
Site 13
T172
S
L
F
Q
T
S
H
T
L
H
L
S
H
L
N
Site 14
S176
T
S
H
T
L
H
L
S
H
L
N
R
F
P
A
Site 15
S195
G
R
L
D
Q
G
R
S
D
D
Y
D
S
K
K
Site 16
Y198
D
Q
G
R
S
D
D
Y
D
S
K
K
R
K
Q
Site 17
S200
G
R
S
D
D
Y
D
S
K
K
R
K
Q
R
A
Site 18
Y224
P
R
H
D
L
P
P
Y
R
V
H
L
T
P
Y
Site 19
T229
P
P
Y
R
V
H
L
T
P
Y
T
V
D
S
P
Site 20
Y231
Y
R
V
H
L
T
P
Y
T
V
D
S
P
I
C
Site 21
T232
R
V
H
L
T
P
Y
T
V
D
S
P
I
C
D
Site 22
Y247
F
L
E
L
Q
R
R
Y
R
S
L
L
V
P
S
Site 23
S249
E
L
Q
R
R
Y
R
S
L
L
V
P
S
D
F
Site 24
S270
W
L
S
A
F
P
L
S
Q
P
F
S
L
H
H
Site 25
S274
F
P
L
S
Q
P
F
S
L
H
H
P
S
R
I
Site 26
S279
P
F
S
L
H
H
P
S
R
I
Q
V
S
S
E
Site 27
S285
P
S
R
I
Q
V
S
S
E
K
E
A
A
P
D
Site 28
T299
D
A
G
A
E
P
I
T
A
D
S
D
P
A
Y
Site 29
S302
A
E
P
I
T
A
D
S
D
P
A
Y
S
S
K
Site 30
Y306
T
A
D
S
D
P
A
Y
S
S
K
V
L
L
L
Site 31
S308
D
S
D
P
A
Y
S
S
K
V
L
L
L
S
S
Site 32
S314
S
S
K
V
L
L
L
S
S
P
G
L
E
E
L
Site 33
S315
S
K
V
L
L
L
S
S
P
G
L
E
E
L
Y
Site 34
T338
D
M
A
E
P
R
E
T
P
E
H
P
L
K
Q
Site 35
S367
V
G
G
E
W
S
P
S
L
D
G
L
D
P
Q
Site 36
Y410
W
R
F
A
E
F
Q
Y
L
Q
P
G
P
P
R
Site 37
T421
G
P
P
R
R
L
Q
T
V
V
V
Y
L
P
D
Site 38
T454
A
A
E
A
A
P
P
T
Q
E
A
Q
G
E
T
Site 39
T464
A
Q
G
E
T
E
P
T
E
Q
A
P
D
A
L
Site 40
T477
A
L
E
Q
A
A
D
T
S
R
R
N
A
E
T
Site 41
S478
L
E
Q
A
A
D
T
S
R
R
N
A
E
T
P
Site 42
T484
T
S
R
R
N
A
E
T
P
E
A
T
T
Q
Q
Site 43
T488
N
A
E
T
P
E
A
T
T
Q
Q
E
T
D
T
Site 44
T489
A
E
T
P
E
A
T
T
Q
Q
E
T
D
T
D
Site 45
T493
E
A
T
T
Q
Q
E
T
D
T
D
L
P
E
A
Site 46
T495
T
T
Q
Q
E
T
D
T
D
L
P
E
A
P
P
Site 47
S534
R
R
P
K
E
R
I
S
F
E
V
M
V
L
A
Site 48
Y554
M
L
Q
R
D
F
G
Y
R
V
Y
K
M
L
L
Site 49
Y557
R
D
F
G
Y
R
V
Y
K
M
L
L
S
L
P
Site 50
S569
S
L
P
E
K
V
V
S
P
P
E
P
E
K
E
Site 51
T609
A
Q
N
E
G
P
A
T
E
S
E
A
P
L
K
Site 52
S611
N
E
G
P
A
T
E
S
E
A
P
L
K
E
D
Site 53
S626
G
L
L
P
K
P
L
S
S
G
G
E
E
E
E
Site 54
S627
L
L
P
K
P
L
S
S
G
G
E
E
E
E
K
Site 55
S640
E
K
P
R
G
E
A
S
E
D
L
C
E
M
A
Site 56
S671
A
G
A
K
L
E
D
S
E
V
R
S
V
A
S
Site 57
S675
L
E
D
S
E
V
R
S
V
A
S
N
Q
S
E
Site 58
S678
S
E
V
R
S
V
A
S
N
Q
S
E
M
E
F
Site 59
S681
R
S
V
A
S
N
Q
S
E
M
E
F
S
S
L
Site 60
S686
N
Q
S
E
M
E
F
S
S
L
Q
D
M
P
K
Site 61
S687
Q
S
E
M
E
F
S
S
L
Q
D
M
P
K
E
Site 62
Y719
F
D
A
N
W
C
G
Y
L
H
R
R
D
L
E
Site 63
T750
Q
L
V
S
R
V
V
T
Q
N
I
C
Q
Y
R
Site 64
Y756
V
T
Q
N
I
C
Q
Y
R
S
L
Q
Y
S
R
Site 65
S758
Q
N
I
C
Q
Y
R
S
L
Q
Y
S
R
Q
E
Site 66
Y761
C
Q
Y
R
S
L
Q
Y
S
R
Q
E
G
L
D
Site 67
S762
Q
Y
R
S
L
Q
Y
S
R
Q
E
G
L
D
G
Site 68
S789
L
L
P
P
P
G
K
S
T
K
P
G
A
A
P
Site 69
S804
T
E
H
K
A
L
V
S
H
N
G
S
L
I
N
Site 70
S808
A
L
V
S
H
N
G
S
L
I
N
V
G
S
L
Site 71
S814
G
S
L
I
N
V
G
S
L
L
Q
R
A
E
Q
Site 72
S824
Q
R
A
E
Q
Q
D
S
G
R
L
Y
L
E
N
Site 73
Y828
Q
Q
D
S
G
R
L
Y
L
E
N
K
I
H
T
Site 74
S843
L
E
L
K
L
E
E
S
H
N
R
F
S
A
T
Site 75
S848
E
E
S
H
N
R
F
S
A
T
E
V
T
N
K
Site 76
T874
R
L
A
E
A
E
E
T
A
R
T
A
E
R
Q
Site 77
T877
E
A
E
E
T
A
R
T
A
E
R
Q
K
S
Q
Site 78
S883
R
T
A
E
R
Q
K
S
Q
L
Q
R
L
L
Q
Site 79
T897
Q
E
L
R
R
R
L
T
P
L
Q
L
E
I
Q
Site 80
S912
R
V
V
E
K
A
D
S
W
V
E
K
E
E
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation