PhosphoNET

           
Protein Info 
   
Short Name:  WWC1
Full Name:  Protein KIBRA
Alias:  KIAA0869; KIBRA; WW and C2 domain containing 1
Type:  Uncharacterized protein
Mass (Da):  125301
Number AA:  1113
UniProt ID:  Q8IX03
International Prot ID:  IPI00217340
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y23RDFDGKVYYIDHTNR
Site 2Y24DFDGKVYYIDHTNRT
Site 3T32IDHTNRTTSWIDPRD
Site 4S33DHTNRTTSWIDPRDR
Site 5Y41WIDPRDRYTKPLTFA
Site 6T42IDPRDRYTKPLTFAD
Site 7T46DRYTKPLTFADCISD
Site 8Y63PLGWEEAYDPQVGDY
Site 9Y70YDPQVGDYFIDHNTK
Site 10Y99QEHMLKDYLVVAQEA
Site 11Y114LSAQKEIYQVKQQRL
Site 12Y128LELAQQEYQQLHAVW
Site 13S141VWEHKLGSQVSLVSG
Site 14S144HKLGSQVSLVSGSSS
Site 15S147GSQVSLVSGSSSSSK
Site 16S149QVSLVSGSSSSSKYD
Site 17S150VSLVSGSSSSSKYDP
Site 18S151SLVSGSSSSSKYDPE
Site 19S153VSGSSSSSKYDPEIL
Site 20Y155GSSSSSKYDPEILKA
Site 21S169AEIATAKSRVNKLKR
Site 22S203KKIDKKMSDAQGSYK
Site 23T221AQAVLRETKAIKKAI
Site 24S241EKQDLIKSLAMLKDG
Site 25T251MLKDGFRTDRGSHSD
Site 26S255GFRTDRGSHSDLWSS
Site 27S257RTDRGSHSDLWSSSS
Site 28S261GSHSDLWSSSSSLES
Site 29S262SHSDLWSSSSSLESS
Site 30S263HSDLWSSSSSLESSS
Site 31S264SDLWSSSSSLESSSF
Site 32S265DLWSSSSSLESSSFP
Site 33S268SSSSSLESSSFPLPK
Site 34S269SSSSLESSSFPLPKQ
Site 35S270SSSLESSSFPLPKQY
Site 36Y277SFPLPKQYLDVSSQT
Site 37S282KQYLDVSSQTDISGS
Site 38S287VSSQTDISGSFGINS
Site 39S289SQTDISGSFGINSNN
Site 40Y308KVRLRLRYEEAKRRI
Site 41S336AWPGVLDSERDRLIL
Site 42S358LKEMRFISPRKWTQG
Site 43T363FISPRKWTQGEVEQL
Site 44T387DLQAARDTQSKALTE
Site 45S389QAARDTQSKALTERL
Site 46T393DTQSKALTERLKLNS
Site 47S400TERLKLNSKRNQLVR
Site 48S421RQVATLHSQLKSLSS
Site 49S425TLHSQLKSLSSSMQS
Site 50S427HSQLKSLSSSMQSLS
Site 51S428SQLKSLSSSMQSLSS
Site 52S429QLKSLSSSMQSLSSG
Site 53S432SLSSSMQSLSSGSSP
Site 54S434SSSMQSLSSGSSPGS
Site 55S435SSMQSLSSGSSPGSL
Site 56S437MQSLSSGSSPGSLTS
Site 57S438QSLSSGSSPGSLTSS
Site 58S441SSGSSPGSLTSSRGS
Site 59T443GSSPGSLTSSRGSLV
Site 60S444SSPGSLTSSRGSLVA
Site 61S445SPGSLTSSRGSLVAS
Site 62S448SLTSSRGSLVASSLD
Site 63S452SRGSLVASSLDSSTS
Site 64S453RGSLVASSLDSSTSA
Site 65S457VASSLDSSTSASFTD
Site 66T458ASSLDSSTSASFTDL
Site 67S459SSLDSSTSASFTDLY
Site 68S461LDSSTSASFTDLYYD
Site 69T463SSTSASFTDLYYDPF
Site 70Y466SASFTDLYYDPFEQL
Site 71Y467ASFTDLYYDPFEQLD
Site 72S475DPFEQLDSELQSKVE
Site 73T499FRPSGCITTIHEDEV
Site 74T509HEDEVAKTQKAEGGG
Site 75S523GRLQALRSLSGTPKS
Site 76S525LQALRSLSGTPKSMT
Site 77T527ALRSLSGTPKSMTSL
Site 78S530SLSGTPKSMTSLSPR
Site 79T532SGTPKSMTSLSPRSS
Site 80S533GTPKSMTSLSPRSSL
Site 81S535PKSMTSLSPRSSLSS
Site 82S538MTSLSPRSSLSSPSP
Site 83S539TSLSPRSSLSSPSPP
Site 84S541LSPRSSLSSPSPPCS
Site 85S542SPRSSLSSPSPPCSP
Site 86S544RSSLSSPSPPCSPLM
Site 87S548SSPSPPCSPLMADPL
Site 88S564AGDAFLNSLEFEDPE
Site 89S573EFEDPELSATLCELS
Site 90T575EDPELSATLCELSLG
Site 91S580SATLCELSLGNSAQE
Site 92S584CELSLGNSAQERYRL
Site 93T596YRLEEPGTEGKQLGQ
Site 94S626SAAVSDESVAGDSGV
Site 95S637DSGVYEASVQRLGAS
Site 96S651SEAAAFDSDESEAVG
Site 97Y668RIQIALKYDEKNKQF
Site 98T710LPCSESTTCLFRTRP
Site 99S721RTRPLDASDTLVFNE
Site 100Y736VFWVSMSYPALHQKT
Site 101T743YPALHQKTLRVDVCT
Site 102T750TLRVDVCTTDRSHLE
Site 103T751LRVDVCTTDRSHLEE
Site 104S754DVCTTDRSHLEECLG
Site 105S773SLAEVCRSGERSTRW
Site 106S777VCRSGERSTRWYNLL
Site 107T778CRSGERSTRWYNLLS
Site 108Y781GERSTRWYNLLSYKY
Site 109Y788YNLLSYKYLKKQSRE
Site 110S833EKRQEGRSSTQTLED
Site 111S834KRQEGRSSTQTLEDS
Site 112T835RQEGRSSTQTLEDSW
Site 113T837EGRSSTQTLEDSWRY
Site 114S841STQTLEDSWRYEETS
Site 115S848SWRYEETSENEAVAE
Site 116T872EGEEDVFTEKASPDM
Site 117S876DVFTEKASPDMDGYP
Site 118Y882ASPDMDGYPALKVDK
Site 119T893KVDKETNTETPAPSP
Site 120T895DKETNTETPAPSPTV
Site 121S899NTETPAPSPTVVRPK
Site 122T901ETPAPSPTVVRPKDR
Site 123T912PKDRRVGTPSQGPFL
Site 124S914DRRVGTPSQGPFLRG
Site 125S922QGPFLRGSTIIRSKT
Site 126T923GPFLRGSTIIRSKTF
Site 127S927RGSTIIRSKTFSPGP
Site 128T929STIIRSKTFSPGPQS
Site 129S931IIRSKTFSPGPQSQY
Site 130S936TFSPGPQSQYVCRLN
Site 131Y938SPGPQSQYVCRLNRS
Site 132S945YVCRLNRSDSDSSTL
Site 133S947CRLNRSDSDSSTLSK
Site 134S949LNRSDSDSSTLSKKP
Site 135S950NRSDSDSSTLSKKPP
Site 136T951RSDSDSSTLSKKPPF
Site 137S953DSDSSTLSKKPPFVR
Site 138S962KPPFVRNSLERRSVR
Site 139S967RNSLERRSVRMKRPS
Site 140S974SVRMKRPSSVKSLRS
Site 141S975VRMKRPSSVKSLRSE
Site 142S978KRPSSVKSLRSERLI
Site 143S981SSVKSLRSERLIRTS
Site 144S988SERLIRTSLDLELDL
Site 145T1006RTWHSQLTQEISVLK
Site 146S1010SQLTQEISVLKELKE
Site 147S1024EQLEQAKSHGEKELP
Site 148S1081VHRLRGQSCKEPPEV
Site 149S1090KEPPEVQSFREKMAF
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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